串联催化聚合物纳米反应器的构筑及抗肿瘤性能研究

21875234
2018
B0507.医用材料化学
葛治伸
面上项目
教授
中国科学技术大学
66万元
药物控制释放;肿瘤微环境;抗癌纳米药物;囊泡;多功能纳米载体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ferrocene-containing polymersome nanoreactors for synergistically amplified tumor-specific chemodynamic therapy 期刊论文 Yuheng Wang;Shuang Zhang;Jingbo Wang;Qinghao Zhou;Jean Felix Mukerabigwi;Wendong Ke;Nannan Lu;Zhishen Ge
2 Covalent Organic Framework Nanocarriers of Singlet Oxygen for Oxygen-Independent Concurrent Photothermal/Photodynamic Therapy to Ablate Hypoxic Tumors 期刊论文 Debabrata Dutta;Jingbo Wang;Xiang Li;Qinghao Zhou;Zhishen Ge
3 Glutathione-Triggered Mitochondria-Targeting Reassembly from Polymeric Micelles to Nanofibers for a Synergistic Anticancer Effect 期刊论文 Jingbo Wang;Qinghao Zhou;Xiang Li;Debabrata Dutta;Zhishen Ge
4 一种基于硫内酯化学构筑的多功能非病毒基因输送载体聚合物 专利 葛治伸;查增仕
5 Hypoxia-Responsive Polyprodrug Nanocarriers for Near-Infrared Light-Boosted Photodynamic Chemotherapy 期刊论文 Debabrata Dutta;Qinghao Zhou;Jean Felix Mukerabigwi;Nannan Lu;Zhishen Ge
6 一种嵌段聚合物肿瘤放疗曾敏剂及其制备方法 专利 葛治伸;赵凯杰;尹伟;柯文冬
7 一种肿瘤放射治疗增敏剂聚合物及其制备方法、胶束纳米粒子及其应用 专利 葛治伸;尹伟
8 Polymersome Nanoreactor‐Mediated Combination Chemodynamic‐Immunotherapy via ROS Production and Enhanced STING Activation 期刊论文 Qinghao Zhou;Yuheng Wang;Xiang Li;Nannan Lu;Zhishen Ge
9 Membrane-cross-linked polymersomes with tumor pH-tunable selective permeability as intelligent nanoreactors and drug delivery vehicles 期刊论文 Abd Al-Wali Mohammed M. Japir;Nannan Lu;Yuheng Wang;Jean Felix Mukerabigwi;Qinghao Zhou;Zhishen Ge
10 Therapeutic Polymersome Nanoreactors with Tumor-Specific Activable Cascade Reactions for Cooperative Cancer Therapy 期刊论文 Wendong Ke;Junjie Li;Fathelrahman Mohammed;Yuheng Wang;Kazuko Tou;Xueying Liu;Panyue Wen;Hiroaki Kinoh;Yasutaka Anraku;Huabing Chen;Kazunori Kataoka;Zhishen Ge
11 Protein-Delivering Nanocomplexes with Fenton Reaction-Triggered Cargo Release to Boost Cancer Immunotherapy 期刊论文 Xiang Li;Qinghao Zhou;Abd Al-Wali Mohammed M. Japir;Debabrata Dutta;Nannan Lu;Zhishen Ge
12 Glutathione and Reactive Oxygen Species Dual-Responsive Block Copolymer Prodrugs for Boosting Tumor Site-Specific Drug Release and Enhanced Antitumor Efficacy 期刊论文 Wei Yin;Wendong Ke;Nannan Lu;Yuheng Wang;Abd Al-Wali Mohammed M. Japir;Fathelrahman Mohammed;Yi Wang;Yueyin Pan;Zhishen Ge
13 Acid-responsive endosomolytic polymeric nanoparticles with amplification of intracellular oxidative stress for prodrug delivery and activation 期刊论文 Nannan Lu;Longchang Xi;Zengshi Zha;Yuheng Wang;Xinghua Han;Zhishen Ge
14 Length effect of stimuli-responsive block copolymer prodrug filomicelles on drug delivery efficiency. 期刊论文 Wendong Ke;Nannan Lu;Abd Al-Wali Mohammed M. Japir;Qinghao Zhou;Longchang Xi;Yuheng Wang;Debabrata Dutta;Min Zhou;Yueyin Pan;Zhishen Ge
15 ROS-Responsive Polymeric Nanocarriers with Photoinduced Exposure of Cell-Penetrating Moieties for Specific Intracellular Drug Delivery 期刊论文 Fathelrahman Mohammed;Wendong Ke;Jean Felix Mukerabigwi;Abd Al-Wali Mohammed M. Japir;Alhadi Ibrahim;Yuheng Wang;Zengshi Zha;Nannan Lu;Min Zhou;Zhishen Ge
16 Multifunctional Mesoporous Hollow Cobalt Sulfide Nanoreactors for Synergistic Chemodynamic/Photodynamic/Photothermal Therapy with Enhanced Efficacy 期刊论文 Xiang Li;Mei He;Qinghao Zhou;Debabrata Dutta;Nannan Lu;Shikuo Li;Zhishen Ge
17 Dual‐Targeting Polymeric Nanocarriers to Deliver ROS‐Responsive Prodrugs and Combat Multidrug Resistance of Cancer Cells 期刊论文 Longchang Xi;Jingbo Wang;Yuheng Wang;Zhishen Ge
18 Reduction-Responsive Polymer Prodrug Micelles with Enhanced Endosomal Escape Capability for Efficient Intracellular Translocation and Drug Release 期刊论文 Alhadi Ibrahim;Etienne Twizeyimana;Nannan Lu;Wendong Ke;Jean Felix Mukerabigwi;Fathelrahman Mohammed;Abd Al-Wali Mohammed M. Japir;Zhishen Ge
19 Hypoxia-responsive block copolymer polyprodrugs for complementary photodynamic-chemotherapy 期刊论文 Qinghao Zhou;Fathelrahman Mohammed;Yuheng Wang;Jingbo Wang;Nannan Lu;Junjie Li;Zhishen Ge
20 Tumor-dilated polymersome nanofactories for enhanced enzyme prodrug chemo-immunotherapy 期刊论文 Abd Al-Wali Mohammed M. Japir;Wendong Ke;Junjie Li;Jean Felix Mukerabigwi;Alhadi Ibrahim;Yuheng Wang;Xiang Li;Qinghao Zhou;Fathelrahman Mohammed;Zhishen Ge
21 Nanoparticle‐Mediated STING Agonist Delivery for Enhanced Cancer Immunotherapy 期刊论文 Qinghao Zhou;Yu Zhou;Taiyuan Li;Zhishen Ge
22 Cisplatin Resistance Reversal of Lung Cancers by Tumor Acidity-Activable Vesicular Nanoreactors via Tumor Oxidative Stress Amplification 期刊论文 Jean Felix Mukerabigwi;Yu Han;Nannan Lu;Wendong Ke;Yuheng Wang;zhishen Ge
23 Block copolymer prodrugs: Synthesis, self-assembly, and applications for cancer therapy 期刊论文 Dutta Debabrata;Ke Wendong;Xi Longchang;Yin Wei;Zhou Min;Ge Zhishen
24 Polymersome nanoreactors with tumor pH-triggered selective membrane permeability for prodrug delivery, activation, and combined oxidation-chemotherapy 期刊论文 Jean Felix Mukerabigwi;Wei Yin;Zengshi Zha;Wendong Ke;Yuheng Wang;Weijian Chen;Abd Al-Wali Mohammed Mohammed Japir;Yi Wang;Zhishen Ge
25 Integrated block copolymer prodrug nanoparticles for combination of tumor oxidative stress amplification and ROS-responsive drug release 期刊论文 Wei Yin;Wendong Ke;Weijian Chen;Longchang Xi;Qinghao Zhou;Jean Felix Mukerabigwi;Zhishen Ge
26 一种基质金属蛋白酶响应性聚合物药物载体及其制备方法和应用 专利 葛治伸;柯文冬
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