基于雌激素受体及芳香化酶靶向识别分析新方法及其在抗乳腺癌药物分析中应用

21375101
2013
B0406.生命与公共安全分析
陈子林
面上项目
教授
武汉大学
80万元
雌激素受体;毛细管电泳/电色谱-质谱;芳香化酶;抗肿瘤药物;药物分析
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Efficient bienzyme nanocomposite film for chiral recognition of L-tryptophan, L-phenylalanine and L-tyrosine 期刊论文 Wang Lili;Gong Wencheng;Wang Fang;Yu Zhenya;Chen Zilin
2 Covalent immobilization of graphene onto stainless steel wire for jacket-free stir bar sorptive extraction 期刊论文 Zhang Wenpeng;Zhang Zixin;Zhang Juan;Meng Jiawei;Bao Tao;Chen Zilin
3 Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N,N '-dicyclohexylcarbodiimide derivatization 期刊论文 Chen Jing;Zhang Juan;Zhang Wenpeng;Chen Zilin
4 Determination of breath gas composition of lung cancer patients using gas chromatography/mass spectrometry with monolithic material sorptive extraction 期刊论文 Ma Wen;Gao Peng;Fan Jun;Hashi Yuki;Chen Zilin
5 一种开管毛细管电色谱柱的制备方法 专利 陈子林;张娟
6 Analysis of active components in Radix Tinosporae by nonaqueous capillary electrophoresis-mass spectrometry 期刊论文 Yikun Liu;Wei Zhou;Zhenkun Mao;Xiaoyan Liao;Zilin Chen
7 一种石墨烯开管电色谱柱的制备方法 专利 陈子林;张娟
8 Trypsin inhibitor screening in traditional Chinese medicine by using an immobilized enzyme microreactor in capillary and molecular docking study 期刊论文 Cheng Mengxia;Chen Zilin
9 Jacket-free stir bar sorptive extraction with bio-inspired polydopamine-functionalized immobilization of cross-linked polymer on stainless steel wire 期刊论文 Zhang Zixin;Zhang Wenpeng;Bao Tao;Chen Zilin
10 Interaction with Deoxyribonucleic Acid and Determination of Orientin in Lophatherum gracile Brongn by High-Performance Liquid Chromatography with Amperometric Detection 期刊论文 Wang Fang;Yan Fangfang;Long Yuling;Wang Lili;Chen Zilin
11 一种聚四氟乙烯微萃取柱及其制备方法 专利 陈子林;张文鹏
12 Polydopamine-supported immobilization of covalent-organic framework-5 in capillary as stationary phase for electrochromatographic separation 期刊论文 Bao Tao;Tang Pingxiu;Kong Deying;Mao Zhenkun;Chen Zilin
13 Enhanced amperometric response of a glucose oxidase and horseradish peroxidase based bienzyme glucose biosensor modified with a film of polymerized toluidine blue containing reduced graphene oxide 期刊论文 Wang Fang;Gong Wencheng;Wang Lili;Chen Zilin
14 Monolithic column modified with bifunctional ionic liquid and styrene stationary phases for capillary electrochromatography 期刊论文 Mao Zhenkun;Chen Zilin
15 Graphene/polydopamine-modified polytetrafluoroethylene microtube for the sensitive determination of three active components in Fructus Psoraleae by online solid-phase microextraction with high-performance liquid chromatography 期刊论文 Zhang Wenpeng;Zhou Wei;Chen Zilin
16 An immobilized carboxyl containing metal-organic framework-5 stationary phase for open-tubular capillary electrochromatography 期刊论文 Bao Tao;Tang Pingxiu;Mao Zhenkun;Chen Zilin
17 Tyrosinase inhibitor screening in traditional Chinese medicines by electrophoretically mediated microanalysis 期刊论文 Tang Lilin;Zhang Wenpeng;Zhao Haiyan;Chen Zilin
18 一种不锈钢萃取搅拌棒及其制备方法 专利 陈子林;张文鹏
19 一种不锈钢萃取搅拌棒及其制备方法 专利 陈子林;张文鹏;张紫鑫
20 Electrochemically modified carbon fiber bundles as selective sorbent for online solid-phase microextraction of sulfonamides 期刊论文 Ling Xu;Zhang Wenpeng;Chen Zilin
21 Preparation of a novel molecularly imprinted polymer for the highly selective extraction of baicalin 期刊论文 Liu Xiao;Zhang Wenpeng;Chen Zilin
22 Polydopamine-functionalized poly(ether ether ketone) tube for capillary electrophoresis-mass spectrometry 期刊论文 Zhou Wei;Zhang Wenpeng;Liu Yikun;Yu Xinhong;Chen Zilin
23 Polydopamine-assisted immobilization of zeolitic imidazolate framework-8 for open-tubular capillary electrochromatography 期刊论文 Li Yilin;Bao Tao;Chen Zilin
24 COF-1-modified magnetic nanoparticles for highly selective and efficient solid-phase microextraction of paclitaxel 期刊论文 Chen Yuling;Chen Zilin
25 Cathepsin B inhibitor screeningin traditional Chinese medicines by electrophoretically mediated microanalysis 期刊论文 Jing Han;Zilin Chen
26 Layered double hydroxides based ion exchange extraction for high sensitive analysis of non-steroidal anti-inflammatory drugs 期刊论文 Zhou Wei;Wang Chenlu;Liu Yikun;Zhang Wenpeng;Chen Zilin
27 Selective recognition of D-tryptophan from d/l-tryptophan mixtures in the presence of Cu(II) by electropolymerized L-lysine film 期刊论文 Wang Fang;Gong Wencheng;Wang Lili;Chen Zilin
28 An etched polyether ether ketone tube covered with immobilized graphene oxide for online solid phase microextraction of quaternary alkaloids prior to their quantitation by HPLC-MS/MS 期刊论文 Wang Chenlu;Zhou Wei;Liao Xiaoyan;Zhang Wenpeng;Chen Zilin
29 Simultaneous detection of eight active components in Radix Tinosporae by ultra high performance liquid chromatography coupled with electrospray tandem mass spectrometry 期刊论文 Xiang Qiuyue;Hashi Yuki;Chen Zilin
30 Polytetrafluoroethylene-jacketed stirrer modified with graphene oxide and polydopamine for the efficient extraction of polycyclic aromatic hydrocarbons 期刊论文 Zhang Zinxin;Mwadini Mwadini Ahmada;Chen Zilin
31 Enhancement of capillary electrochromatographic separation performance by conductive polymer in a layer-by-layer fabricated graphene stationary phase 期刊论文 Zhang Juan;Zhang Wenpeng;Bao Tao;Chen Zilin
32 Simultaneous and highly sensitive quantification of five bioactive components in Fructus Psoraleae and in rat plasma by HPLC with fluorescence detection 期刊论文 Chen Ying;Xiang Qiuyue;Chen Zilin
33 Novel molecularly imprinted magnetic nanoparticles for the selective extraction of protoberberine alkaloids in herbs and rat plasma 期刊论文 Meng Jiawei;Zhang Wenpeng;Bao Tao;Chen Zilin
34 Growth of metal-organic framework HKUST-1 in capillary using liquid-phase epitaxy for open-tubular capillary electrochromatography and capillary liquid chromatography 期刊论文 Bao Tao;Zhang Juan;Zhang Wenpeng;Chen Zilin
35 Mussel-inspired polydopamine-assisted hydroxyapatite as the stationary phase for capillary electrochromatography 期刊论文 Zhang Juan;Zhang Wenpeng;Bao Tao;Chen Zilin
36 Polydopamine-based immobilization of zeolitic imidazolate framework-8 for in-tube solid-phase microextraction 期刊论文 Zhang Juan;Zhang Wenpeng;Bao Tao;Chen Zilin
37 Electrochemical detection of DNA methylation using a glassy carbon electrode modified with a composite made from carbon nanotubes and beta-cyclodextrin 期刊论文 Wang Lili;Yu Feiyue;Wang Fang;Chen Zilin
38 基于金属有机骨架材料的开管毛细管的制备方法 专利 陈子林;包涛
39 一种在聚丙烯表面固定层状双氢氧化物的方法及其应用 专利 陈子林;张文鹏;周韦
40 Screening of neuraminidase inhibitors from traditional Chinese medicine by transverse diffusion mediated capillary microanalysis 期刊论文 Zhao Haiyan;Chen Zilin
41 修饰碳纤维填充聚醚醚酮管固相微萃取柱及其制备方法 专利 陈子林;凌旭;张文鹏
42 Thiol-based non-injection synthesis of near-infrared Ag2S/ZnS core/shell quantum dots 期刊论文 Jiang Peng;Wang Rong;Chen Zilin
43 Novel polymeric monolith materials with a beta-cyclodextrin-graphene composite for the highly selective extraction of methyl jasmonate 期刊论文 Yu Xinhong;Ling Xu;Zou Li;Chen Zilin
44 A covalent organic framework-based magnetic sorbent for solid phase extraction of polycyclic aromatic hydrocarbons, and its hyphenation to HPLC for quantitation 期刊论文 Wang Rong;Chen Zilin
45 Novel Zn-based MOFs stationary phase with large pores for capillary electrochromatography 期刊论文 Tang Pingxiu;Bao Tao;Chen Zilin
46 Evaluation of the interaction between hydroxyapatite and bisphosphonate by nonlinear capillary electrochromatography 期刊论文 Kong Deying;Chen Zilin
47 Electroosmotic pump-supported molecularly imprinted monolithic column for capillary chromatographic separation of nitrophenol isomers 期刊论文 Wu Yue;Zhang Wenpeng;Chen Ying;Chen Zilin
48 Screening of neuraminidase inhibitors from traditional Chinese medicines by integrating capillary electrophoresis with immobilized enzyme microreactor 期刊论文 Zhao Haiyan;Chen Zilin
49 Electrochemically deposited conductive composite sorbent for highly efficient online solid-phase microextraction of jasmonates in plant samples 期刊论文 Ling Xu;Chen Zilin
50 Universal biomimetic preparation and immobilization of layered double hydroxide films and adsorption behavior 期刊论文 Zhou Wei;Zhang Wenpeng;Chen Zilin
51 Polymeric monolith column composited with multiwalled carbon nanotubes-beta-cyclodextrin for the selective extraction of psoralen and isopsoralen 期刊论文 Ling Xu;Zou Li;Chen Zilin
52 in situ immobilization of layered double hydroxides as stationary phase for capillary electrochromatography 期刊论文 Xinhong Yu;Zilin Chen
53 Study on pharmacokinetic and tissue distribution of lycorine in mice plasma and tissues by liquid chromatography-mass spectrometry 期刊论文 Ren Liping;Zhao Haiyan;Chen Zilin
54 Sensitive and simultaneous determination of active components in Lycoris radiata and rat plasma by HPLC with fluorescence detection 期刊论文 Xiang Qiuyue;Chen Ying;Chen Zilin
55 In situ synthesis of the imine-based covalent organic framework LZU1 on the inner walls of capillaries for electrochromatographic separation of nonsteroidal drugs and amino acids 期刊论文 Kong Deying;Bao Tao;Chen Zilin
56 Selective and sensitive determination of protoberberines by capillary electrophoresis coupled with molecularly imprinted microextraction 期刊论文 Zhang Wenpeng;Li Yilin;Chen Zilin
57 Screening of tyrosinase inhibitors by capillary electrophoresis with immobilized enzyme microreactor and molecular docking 期刊论文 Cheng Mengxia;Chen Zilin
58 Ligand effect on the synthesis of emission-tunable near-infrared Ag2S quantum dots 期刊论文 Jiang Peng;Chen Zilin
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