具有细胞内选择性输运和同步荧光触发特性的反应性高分子组装体构筑

21674103
2016
B0507.医用材料化学
刘世勇
面上项目
教授
中国科学技术大学
68万元
响应性高分子;肿瘤微环境;细胞成像;嵌段共聚物;高分子囊泡
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Photoregulated Cross-Linking of Superparamagnetic Iron Oxide Nanoparticle (SPION) Loaded Hybrid Nanovectors with Synergistic Drug Release and Magnetic Resonance (MR) Imaging Enhancement 期刊论文 Zhu Kangning;Deng Zhengyu;Liu Guhuan;Hu Jinming;Liu Shiyong
2 Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation 期刊论文 Zhu Kangning;Liu Guhuan;Zhang Guoying;Hu Jinming;Liu Shiyong
3 Photo- and Reduction-Responsive Polymersomes for Programmed Release of Small and Macromolecular Payloads 期刊论文 Sun Ziqiang;Liu Guhuan;Hu Jinming;Liu Shiyong
4 含荧光发色团的缀合物、嵌段共聚物、靶向药物及其制备方法和应用 专利 刘世勇;刘固寰;姜琰琰
5 Emerging Trends in Solution Self-Assembly of Block Copolymers 期刊论文 Deng Zhengyu;Liu Shiyong
6 Cytosolic NQO1 Enzyme-Activated Near-Infrared Fluorescence Imaging and Photodynamic Therapy with Polymeric Vesicles 期刊论文 Yao Chenzhi;Li Yamin;Wang Zhixiong;Song Chengzhou;Hu Xianglong;Liu Shiyong
7 具有荧光发射性质的抗体-药物/探针缀合物及其制备方法和应用 专利 刘世勇;刘固寰;姜琰琰
8 High-Fidelity End-Functionalization of Poly(ethylene glycol) Using Stable and Potent Carbamate Linkages 期刊论文 Shi Shengyu;Yao Chenzhi;Cen Jie;Li Lei;Liu Guhuan;Hu Jinming;Liu Shiyong
9 Photo- and Thermo-Responsive Multicompartment Hydrogels for Synergistic Delivery of Gemcitabine and Doxorubicin 期刊论文 Wang Cheng;Zhang Guoying;Liu Guhuan;Hu Jinming;Liu Shiyong
10 Self-Immolative Nanoparticles for Stimuli-Triggered Activation, Covalent Trapping and Accumulation of in situ Generated Small Molecule Theranostic Fragments 期刊论文 Ding Zexuan;Cen Jie;Wu Yun;Zhong Kai;Liu Guhuan;Hu Jinming;Liu Shiyong
11 Doubly Caged Linker for AND-Type Fluorogenic Construction of Protein/Antibody Bioconjugates and In Situ Quantification 期刊论文 Liu Guhuan;Shi Guohai;Sheng Haoyue;Jiang Yanyan;Liang Haojun;Liu Shiyong
12 Fabrication of pH- and Thermoresponsive Three-Layered Micelles via Host-Guest Interactions 期刊论文 Zhang Jingyan;Zhou Haiou;Liu Hao;Hu Jinming;Liu Shiyong
13 Recent Advances on Stimuli-Responsive Macromolecular Magnetic Resonance Imaging (MRI) Contrast Agents 期刊论文 Hu Jinming;Liu Shiyong
14 酶触发聚合物囊泡-核交联胶束转变用于响应性抗菌剂释放 期刊论文 李亚民;刘世勇
15 两亲性嵌段聚合物及其制备方法、嵌段聚合物囊泡及其制备方法与应用 专利 刘世勇;吴瀚森;刘固寰
16 Near-Infrared Light-Activated Photochemical Internalization of Reduction-Responsive Polyprodrug Vesicles for Synergistic Photodynamic Therapy and Chemotherapy 期刊论文 Zhu Kangning;Liu Guhuan;Hu Jinming;Liu Shiyong
17 Disulfide-Based Self-Immolative Linkers and Functional Bioconjugates for Biological Applications 期刊论文 Deng Zhengyu;Hu Jinming;Liu Shiyong
18 Concurrent Drug Unplugging and Permeabilization of Polyprodrug-Gated Crosslinked Vesicles for Cancer Combination Chemotherapy 期刊论文 Hu Xianglong;Zhai Shaodong;Liu Guhuan;Xing Da;Liang Haojun;Liu Shiyong
19 Conjugate and Block Copolymer Containing Fluorescent Chromophore and Preparation Method Thereof and Use Thereof 专利 Liu Shiyong;Liu Guhuan;Jiang Yanyan
20 Topological Effects of Macrocyclic Polymers: from Precise Synthesis to Biomedical Applications 期刊论文 Hu Jinming;Liu Shiyong
21 Precisely Installing Gold Nanoparticles at the Core/Shell Interface of Micellar Assemblies of Triblock Copolymers 期刊论文 Zhu Kangning;Zhu Zhiyuan;Zhou Haiou;Zhang Jingyan;Liu Shiyong
22 具有荧光发射性质的蛋白质/多肽-聚合物缀合物及其制备方法和应用 专利 刘世勇;刘固寰;姜琰琰
23 含荧光发色团的缀合物、嵌段共聚物及其制备方法和应用 专利 刘世勇;刘固寰;姜琰琰
24 Emerging Applications of Fluorogenic and Non-Fluorogenic Bifunctional Linkers 期刊论文 Liu Guhuan;Hu Jinming;Liu Shiyong
25 Regulating Vesicle Bilayer Permeability and Selectivity via Stimuli-Triggered Polymersome-to-PICsome Transition 期刊论文 Wang Xiaorui;Yao Chenzhi;Zhang Guoying;Liu Shiyong
26 Anti-Inflammatory Polymersomes of Redox-Responsive Polyprodrug Amphiphiles with Inflammation-Triggered Indomethacin Release Characteristics 期刊论文 Tan Jiajia;Deng Zhengyu;Liu Guhuan;Hu Jinming;Liu Shiyong
27 Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates 期刊论文 Deng Zhengyu;Yuan Shuai;Xu Ronald X.;Liang Haojun;Liu Shiyong
28 Controlled Drug Delivery with Nanoassemblies of Redox-Responsive Prodrug and Polyprodrug Amphiphiles 期刊论文 Deng Zhengyu;Liu Shiyong
29 Reactive Oxygen, Nitrogen, and Sulfur Species (RONSS)-Responsive Polymersomes for Triggered Drug Release 期刊论文 Deng Zhengyu;Hu Jinming;Liu Shiyong
30 高分子囊泡渗透性与微结构协同调控 期刊论文 姚陈志;汪枭睿;胡进明;刘世勇
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