改造转录调控蛋白设计构建小分子生物传感器及其在天然产物生物合成研究中的应用
31870072
2018
C2102.合成生物学与生物改造技术
陈伟
面上项目
副教授
中国科学院微生物研究所
59万元
生物转化;蛋白质工程;代谢网络优化;途径改造;生物传感器
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis | 期刊论文 | Chen Wei;Yao Jun;Meng Jie;Han Wenjing;Tao Yong;Chen Yihua;Guo Yixin;Shi Guizhi;He Yang;Jin Jian Ming;Tang Shuang Yan |
| 2 | Whole-Cell Biosensors Aid Exploration of Vanillin Transmembrane Transport | 期刊论文 | Zhang Xuanxuan;He Yang;Wu Zhe;Liu Guoxia;Tao Yong;Jin Jian-Ming;Chen Wei;Tang Shuang-Yan |
| 3 | HpaBC基因、突变体及其应用 | 专利 | 陈伟;姚骏;唐双焱 |
| 4 | Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps | 期刊论文 | Yao Jun;He Yang;Su Nannan;Bharath Sakshibeedu R;Tao Yong;Jin Jian-Ming;Chen Wei;Song Haiwei;Tang Shuang-Yan |
| 5 | Metabolic Engineering for Improved Curcumin Biosynthesis in Escherichia coli | 期刊论文 | Wu Jieyuan;Chen Wei;Zhang Yutong;Zhang Xuanxuan;Jin Jian-Ming;Tang Shuang-Yan |
| 6 | Engineering an SspB-mediated degron for novel controllable protein degradation | 期刊论文 | Lei Yanyan;Chen Wei;Xiang La;Wu Jieyuan;Zhen Zhen;Jin Jian-Ming;Liang Chaoning;Tang Shuang-Yan |
| 7 | Engineering the effector specificity of regulatory proteins for the in vitro detection of biomarkers and pesticide residues | 期刊论文 | Chen Wei;Zhang Xuanxuan;Xiong Dandan;Jin Jian Ming;Tang Shuang Yan |
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