Wnt/β-catenin信号通路在sox9基因介导的hMSCs成软骨分化中的作用及机制研究

81672183
2016
H0605.骨、关节、软组织移植与重建
林剑浩
面上项目
教授
北京大学
60万元
人性别决定区Y框蛋白9;软骨分化;基因转染;骨髓基质干细胞;Wnt/β-catenin信号通路
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The prevalence of rheumatoid arthritis in middle-aged and elderly people living in Naqu City, Tibet, Autonomous Region of China. 期刊论文 Qingxi Zhang;Qiang Liu;Chutong Lin;Yangjin Baima;Hu Li;Hongqiang Gong;Jianhao Lin
2 Inhibition of sterol regulatory element-binding protein-2 ameliorates high-fat diet-induced deterioration of knee cartilage: an osteoarthritis animal model study. 会议论文 Ke Tao;Dan Zhao;Qiang Liu;Rujun Li;Liyi Zhang;Jiaxiang Gao;Yan Ke;Hu Li;Jianhao Lin
3 Activation of Wnt signaling pathway ameliorates deterioration of knee cartilage: an DMM-induced osteoarthritic animal model study. 会议论文 Dan Zhao;Qiang Liu;Hao Liu;Jiaxiang Gao;Liyi Zhang;Rujun Li;Hu Li;Jianhao Lin;Ke Tao
4 巨噬细胞过表达Wnt5a对其炎性反应及共培养体系中MSCs成软骨分化的影响研究 期刊论文 桂先革;曾晖;陶可
5 Effects of Wnt5a signaling-mediated inflammation of macrophages upon cartilage homeostasis. 会议论文 Ke Tao;Jianhao Lin
6 Dual gene transfer of fibroblast growth factor-2 and sox9 via rAAV effects on the chondrogenic and metabolic processes in human BMAs. 会议论文 Ke Tao;Jianhao Lin
7 RUNNING EXERCISES ATTENUATES OSTEOARTHRITIS PROGRESS VIA THE INHIBITION OF CARTILAGE DEGENERATION AND FACILITATION OF SUBCHONDRAL BONE FORMATION: A DMM-INDUCED RAT KNEE OSTEOARTHRITIC MODEL 会议论文 Ke Tao;Jianhao Lin
8 Suppression of sterol regulatory element-binding protein-2 ameliorates the deterioration processes of chondrocytes 会议论文 TAO KE;WANG BIN;XING DAN;LI RU JUN;LI HU;LIN JIAN HAO
9 Imaging features in incident radiographic patellofemoral osteoarthritis: the Beijing Shunyi osteoarthritis (BJS) study 期刊论文 Qiu Y;Lin C;Liu Q;Zhong Q;Tao K;Xing D;Li H;Lin J
10 Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates 期刊论文 Ke Tao;Rey-Rico A;Frisch J;Venkatesan JK;Schmitt G;Madry H;Lin J;Cucchiarini M
11 Dual FGF-2 and SOX9 gene transfer via RAAV Vectors: effects on the chondrogenic and metabolic processes in human bone marrow aspirates 期刊论文 K. Tao Sr;A. Rey-Rico;J.K. Venkatesan;G. Schmitt;H. Madry;J. Lin;M. Cucchiarini
12 Bio-orthopedics a new approach, Gene therapy. 专著 Madry Henning;Orth Patrick;Jegadish Venki;Ke Tao;Goebel Lars;Magali Cucchiarini
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