新型免疫细胞 δβ T 细胞识别配体的功能和结构基础

31030030
2010
C0801.固有免疫
高福
重点项目
研究员
中国科学院微生物研究所
190万元
T;HIV;单克隆TCR;δβ;细胞;蛋白结构
2011-01-01到2014-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance. 期刊论文 Mohammed, Fiyaz|Nam, Gol|Chen, Yong|Qi, Jianxun|Garner, Lee I.|Allen, Rachel L.|Yan, Jinghua|Willcox, Benjamin E.|Gao, George F.|
2 PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid 期刊论文 Wang, Han|Xuan, Yifang|Wang, Qihui|Li, Yan|Zhang, Yanfang|Zheng, Chunfu|Fan, Zheng|Yan, Jinghua|Gao, George F.|
3 Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes 期刊论文 Zhang, Shihong|Liu, Jun|Cheng, Hao|Tan, Shuguang|Qi, Jianxun|Yan, Jinghua|Gao, George F.|
4 H7N9: a low pathogenic avian influenza A virus infecting humans 期刊论文 Liu, Jun|Xiao, Haixia|Wu, Yan|Liu, Di|Qi, Xiaopeng|Shi, Yi|Gao, George F.|
5 Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding 期刊论文 Nam, Gol|Shi, Yi|Ryu, Myongchol|Wang, Qihui|Song, Hao|Liu, Jun|Yan, Jinghua|Qi, Jianxun|Gao, George F.|
6 Characterization of human alpha beta TCR repertoire and discovery of D-D fusion in TCR beta chains 期刊论文 Xiao, Xue|Liu, Fei|Zou, Jing|Wu, Jun|Ma, Juncai|Zhao, Fangqing|Zhou, Xuyu|Gao, George F.|Zhu, Baoli|
7 Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes 期刊论文 Niu, Ling|Cheng, Hao|Zhang, Shihong|Tan, Shuguang|Zhang, Yudan|Qi, Jianxun|Liu, Jun|Gao, George F.|
8 病原微生物与免疫 奖励 高福|高福|
9 N-alpha-Terminal Acetylation for T Cell Recognition: Molecular Basis of MHC Class I-Restricted N-alpha-Acetylpeptide Presentation 期刊论文 Sun, Mingwei|Liu, Jun|Qi, Jianxun|Tefsen, Boris|Shi, Yi|Yan, Jinghua|Gao, George F.|
10 Diverse Peptide Presentation of Rhesus Macaque Major Histocompatibility Complex Class I Mamu-A*02 Revealed by Two Peptide Complex Structures and Insights into Immune Escape of Simian Immunodeficiency Virus 期刊论文 Liu, Jun|Dai, Lianpan|Qi, Jianxun|Gao, Feng|Feng, Youjun|Liu, Wenjun|Yan, Jinghua|Gao, George F.|
11 Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development 期刊论文 Liu, Jun|Zhang, Shihong|Tan, Shuguang|Zheng, Beiwen|Gao, George F.|
12 Conserved epitopes dominate cross-CD8+ T-cell responses against influenza A H1N1 virus among Asian populations 期刊论文 Liu, Jun|Wu, Bin|Zhang, Shihong|Tan, Shuguang|Gao, George F.|
13 A strategy to produce monoclonal antibodies against gp96 by prime-boost regimen using endogenous protein and E. coli heterologously-expressed fragment 期刊论文 Zhang Yu-dan|Cao Sheng|Meng Song-dong|Gao, George Fu|
14 Plasticity of human CD8 alpha alpha binding to peptide-HLA-A*2402 期刊论文 Shi, Yi|Qi, Jianxun|Iwamoto, Aikichi|Gao, George F.|
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