基于膜蛋白定点修饰的重组病毒载体结构基础、输送靶向性及免疫原不良反应关系研究

81530090
2015
H34.药物学
周德敏
重点项目
教授
北京大学
274万元
非天然氨基酸;靶向输送;病毒载体;构效关系;蛋白质定点修饰
2016-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Response and Adaptation of Escherichia coli to Suppression of the Amber Stop Codon 期刊论文 Wang Qian;Sun Tingting;Xu Jianfeng;Shen Zhouxin;Briggs Steven P.;Zhou Demin;Wang Lei
2 Uralsaponins M−Y, Antiviral Triterpenoid Saponins from the Roots ofGlycyrrhiza uralensis 期刊论文 Wei Song;Longlong Si;Shuai Ji;Han Wang;Xiao-mei Fang;Li-yan Yu;Ren-yong Li;Li-na Liang;Demin Zhou;Min Ye
3 Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone 期刊论文 Demin Zhou
4 脆蛇转录组序列的分析和系统发育定位(英文) 期刊论文 祝静静;黎万顺;高虹;徐通;鲍秋颖;郑永祥;周德敏;夏钢
5 A selective NIR-emitting zinc sensor by using Schiff base binding to turn-on excited-state intramolecular proton transfer 期刊论文 Wang Junfeng;Li Yingbo;Duah Ernest;Paruchuri Sailaja;Zhou Demin;Pang Yi
6 Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes 期刊论文 Si Longlong;Meng Kun;Tian Zhenyu;Sun Jiaqi;Li Huiqiang;Zhang Ziwei;Soloveva Veronica;Li Haiwei;Fu Ge;Xia Qing;Xiao Sulong;Zhang Lihe;Zhou Demin
7 Generation of influenza A viruses as live but replication-incompetent virus vaccines 期刊论文 Demin Zhou
8 TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy. 期刊论文 Zhang Jinming;Li Yingbo;Fang Xiefan;Zhou Demin;Wang Yitao;Chen Meiwan
9 组织与脱落细胞中的microRNA表达量检测指示miR-203 在口腔扁平苔藓中的潜在作用 期刊论文 冯震东;史闻;蔡志刚;华红;周德敏
10 Development of next generation adeno-associated viral vectors capable of selective tropism and efficient gene delivery 期刊论文 Demin Zhou
11 A single molecular probe for multi-analyte (Cr3+, Al3+ and Fe3+) detection in aqueous medium and its biological application 期刊论文 Wang Junfeng;Li Yingbo;Patel Nikul G.;Zhang Ge;Zhou Demin;Pang Yi
12 Generation of a caged lentiviral vector through an unnatural amino acid for photo-switchable transduction 期刊论文 Wang Yan;Li Shuai;Tian Zhenyu;Sun Jiaqi;Liang Shuobin;Zhang Bo;Bai Lu;Zhang Yuanjie;Zhou Xueying;Xiao Sulong;Zhang Qiang;Zhang Lihe;Zhang Chuanling;Zhou Demin
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