解码新生隐球菌赖氨酸乙酰化影响真菌毒性的分子机制和调控网络
31870140
2018
C0109.病原真菌学与其他微生物
丁辰
面上项目
教授
东北大学
59万元
基因调控;翻译后修饰;蛋白质组;新生隐球菌;调控网络
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Development of nose-to-brain delivery of ketoconazole by nanostructured lipid carriers against cryptococcal meningoencephalitis in mice | 期刊论文 | Wei Du;Hailong Li;Baocheng Tian;Sixiang Sai;Yiru Gao;Tian Lan;Yang Meng;Chen Ding |
| 2 | Pathogen-Host Interaction Repertoire at Proteome and Posttranslational Modification Levels During Fungal Infections | 期刊论文 | Yanjian Li;Hailong Li;Tianshu Sun;Chen Ding |
| 3 | Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies | 期刊论文 | Wei Du;Yiru Gao;Li Liu;Sixiang Sai;Chen Ding |
| 4 | Fungal acetylome comparative analysis identifies an essential role of acetylation in human fungal pathogen virulence | 期刊论文 | Li Yanjian;Li Hailong;Sui Mingfei;Li Minghui;Wang Jiamei;Meng Yang;Sun Tianshu;Liang Qiaojing;Suo Chenhao;Gao Xindi;Li Chao;Li Zhuoran;Du Wei;Zhang Baihua;Sai Sixiang;Zhang Zhang;Ye Jing;Wang Hongchen;Yue Shang;Li Jiayi;Zhong Manli;Chen Changbin;Qi Shouliang;Lu Ling;Li Dancheng;Ding Chen |
| 5 | Cryptococcal Hsf3 controls intramitochondrial ROS homeostasis by regulating the respiratory process | 期刊论文 | Xindi Gao;Yi Fu;Shengyi Sun;Tingyi Gu;Yanjian Li;Tianshu Sun;Hailong Li;Wei Du;Chenhao Suo;Chao Li;Yiru Gao;Yang Meng;Yue Ni;Sheng Yang;Tian Lan;Sixiang Sai;Jiayi Li;Kun Yu;Ping Wang;Chen Ding |
| 6 | The Role of Copper Homeostasis at the Host-Pathogen Axis: From Bacteria to Fungi | 期刊论文 | Li Chao;Li Yanjian;Ding Chen |
| 7 | Integrative Proteome and Acetylome Analyses of Murine Responses to Cryptococcus neoformans Infection | 期刊论文 | Hailong Li;Yanjian Li;Tianshu Sun;Wei Du;Zhijie Zhang;Dancheng Li;Chen Ding |
| 8 | Unveil the transcriptional landscape at the Cryptococcus-host axis in mice and nonhuman primates | 期刊论文 | Li Hailong;Li Yanjian;Sun Tianshu;Du Wei;Li Chao;Suo Chenhao;Meng Yang;Liang Qiaojing;Lan Tian;Zhong Manli;Yang Sheng;Niu Cheng;Li Dancheng;Ding Chen |
| 9 | Risk factors and biofilm formation analyses of hospital-acquired infection of Candida pelliculosa in a neonatal intensive care unit | 期刊论文 | Zhang Zhijie;Cao Yu;Li Yanjian;Chen Xufang;Ding Chen;Liu Yong |
| 10 | Nutrition-Associated Processes Govern Fungal Pathogenicity | 期刊论文 | Gao Xindi;Fu Yi;Ding Chen |
| 11 | Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain | 期刊论文 | Hailong Li;Xiaoxu Han;Wei Du;Yang Meng;Yanjian Li;Tianshu Sun;Qiaojing Liang;Chao Li;Chenhao Suo;Xindi Gao;Yu Qiu;Wen Tian;Minghui An;Hui Zhang;Yajing Fu;Xiaolin Li;Tian Lan;Sheng Yang;Zining Zhang;Wenqing Geng;Chen Ding;Hong Shang |
| 12 | Calcofluor white-cholesteryl hydrogen succinate conjugate mediated liposomes for enhanced targeted delivery of voriconazole into Candida albicans | 期刊论文 | Wei Liu;Mengshun Li;Baocheng Tian;Xuesong Yang;Wei Du;Xiuwen Wang;Huihui Zhou;Chen Ding;Sixiang Sai |
| 13 | Inhibition of copper transporter 1 prevents alpha-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease | 期刊论文 | Gou De-Hai;Huang Ting-Ting;Li Wen;Gao Xin-Di;Haikal Caroline;Wang Xin-He;Song Dong-Yan;Liang Xin;Zhu Lin;Tang Yong;Ding Chen;Li Jia-Yi |
| 14 | Identification and assessment of pulmonary Cryptococcus neoformans infection by blood serum surface-enhanced Raman spectroscopy | 期刊论文 | Zhu Shanshan;Li Yanjian;Gao Han;Hou Gang;Cui Xiaoyu;Chen Shuo;Ding Chen |
| 15 | Proteomic Analysis of Copper Toxicity in Human Fungal Pathogen Cryptococcus neoformans | 期刊论文 | Tianshu Sun;Yanjian Li;Ying-Xing Li;Hailong Li;Yiyi Gong;Jianqiang Wu;Ya-Ting Ning;Chen Ding;Yingchun Xu |
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