单细胞水平的端粒酶活性可视化检测新方法的研究

21874015
2018
B0403.谱学方法与理论
徐章润
面上项目
教授
东北大学
64万元
端粒酶活性;超高灵敏度;光学检测;信号放大;可视化检测
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Sensitive Multicolor Visual Detection of Exosomes via Dual Signal Amplification Strategy of Enzyme-Catalyzed Metallization of Au Nanorods and Hybridization Chain Reaction 期刊论文 Yingzhi Zhang;Danni Wang;Shuai Yue;Yanbing Lu;Chun-Guang Yang;Jin Fang;Zhang-Run Xu
2 A polydopamine coated mesoporous nanocomposite with robust affinity to horseradish peroxidase based on catecholic adhesion 期刊论文 Dan Song;Lei Chen;Ting Li;Zhangrun Xu
3 Simultaneous quantitative detection of multiple tumor markers in microfluidic nanoliter-volume droplets 期刊论文 Yingzhi Zhang;Wenqi Ye;Chunguang Yang;Zhangrun Xu
4 A nanohybrid of Prussian blue supported by boracic acid-modified g-C3N4 for Raman recognition of cell surface sialic acid and photothermal/photodynamic therapy 期刊论文 Ya-Ning Wang;Wen-Shu Zhang;Xiao-Peng Liu;Yun-Yun Wei;Zhang-Run Xu
5 Alkaline phosphatase-regulated in situ formation of chromogenic probes for multicolor visual sensing of biomarkers 期刊论文 Yun-Yun Wei;Ying-Zhi Zhang;Dan Song;Jin Li;Zhang-Run Xu
6 Microfluidic preparation of polymer-lipid Janus microparticles with staged drug release property 期刊论文 Xiaoting Sun;Rui Guo;Danni Wang;Yunyun Wei;Chunguang Yang;Zhangrun Xu
7 A multicolor-SERS dual-mode pH sensor based on smart nano-in-micro particles 期刊论文 Ying Liu;Shuai Yue;Ya-Ning Wang;Yue Wang;Zhang-Run Xu
8 Label-free detection of exosomes based on ssDNA-modulated oxidase-mimicking activity of CuCo2O4 nanorods 期刊论文 Yingzhi Zhang;Qiwen Su;Dan Song;Jiayuan Fan;Zhangrun Xu
9 In situ monitoring PUVA therapy by using a cell-array chip-based SERS platform 期刊论文 Xiao-Peng Liu;Wen-Shu Zhang;Ya-Ning Wang;Wen-Qi Ye;Zhang-Run Xu
10 A digital microfluidic platform based on a near-infrared light-responsive shape-memory micropillar array 期刊论文 Wen-Qi Ye;Yun-Yun Wei;Dan-Ni Wang;Chun-Guang Yang;Zhang-Run Xu
11 High sensitivity and non-background SERS detection of endogenous hydrogen sulfide in living cells using core-shell nanoparticles 期刊论文 Wen-Shu Zhang;Ya-Ning Wang;Zhang-Run Xu
12 Visual detection of acid phosphatase based on hollow mesoporous manganese dioxide nanospheres 期刊论文 Jin Li;Yun-Yun Wei;Zhang-Run Xu
13 Enhanced chemodynamic therapy at weak acidic pH based on g-C3N4-supported hemin/Au nanoplatform and cell apoptosis monitoring during treatment 期刊论文 Ya-Ning Wang;Dan Song;Wen-Shu Zhang;Zhang-Run Xu
14 Multicolor and photothermal dual-readout biosensor for visual detection of prostate specific antigen 期刊论文 Yunyun Wei;Danni Wang;Yingzhi Zhang;Jinhong Sui;Zhangrun Xu
15 DNA-Engineered iron-based metal-organic framework bio-interface for rapid visual determination of exosomes 期刊论文 Ziling Ding;Yanbing Lu;Yunyun Wei;Dan Song;Zhangrun Xu;Jin Fang
16 Rapid and facile electrospray preparation of CsPbBr3@PMMA fluorescent microspheres for fluorescent detection of ALP in biological samples 期刊论文 Ai-Ling Wang;Jia-Xin Teng;Chun-Guang Yang;Zhang-Run Xu
17 Plasmonic Colorimetric Biosensor for Sensitive Exosome Detection via Enzyme-Induced Etching of Gold Nanobipyramid@MnO2 Nanosheet Nanostructures 期刊论文 Yingzhi Zhang;Junye Jiao;Yunyun Wei;Danni Wang;Chunguang Yang;Zhangrun Xu
18 A biochip based on shell-isolated Au@MnO2 nanoparticle array-enhanced fluorescence effect for simple and sensitive exosome assay 期刊论文 Yingzhi Zhang;Jiayuan Fan;Jing Zhao;Zhangrun Xu
19 Advances in droplet microfluidics for SERS and Raman analysis 期刊论文 Shuai Yue;Jin Fang;Zhangrun Xu
20 Controlled formation of porous CuCo2O4 nanorods with enhanced oxidase and catalase catalytic activities using bimetal-organic frameworks as templates 期刊论文 Dan Song;Ting Li;Yun-Yun Wei;Zhang-Run Xu
21 Structural modulation of heterometallic metal–organic framework via a facile metal-ion-assisted surface etching and structural transformation 期刊论文 Dan Song;Yaning Wang;Ruofei Ma;Zhangrun Xu
22 SERS monitoring of the Fenton degradation reaction based on microfluidic droplets and alginate microparticles 期刊论文 Shuai Yue;Wenqi Ye;Zhangrun Xu
23 ICP-MS and Photothermal Dual-Readout Assay for Ultrasensitive and Point-of-Care Detection of Pancreatic Cancer Exosomes 期刊论文 Yingzhi Zhang;Yunyun Wei;Peng Liu;Xuan Zhang;Zhangrun Xu;Xiaodong Tan;Mingli Chen;Jianhua Wang
24 Highly sensitive monitoring of telomerase activity in living cells based on rapidly triggered cascade amplification reaction 期刊论文 Jie Wang;Xiaopeng Liu;Wanyi Xue;Yunyun Wei;Zhangrun Xu
25 Colloidal photonic crystal array chip based on nanoparticle self-assembly on patterned hydrophobic surface for signal-enhanced fluorescent assay of adenosine 期刊论文 Rui Guo;Dan-Ni Wang;Yun-Yun Wei;Ying-Zhi Zhang;Chun-Guang Yang;Zhang-Run Xu
26 Plasmonic photothermal biosensor for visual detection of tyrosinase and dopamine based on manganese dioxide nanosheets-mediated etching of gold nanorods 期刊论文 Jin Li;Yun-Yun Wei;Xiao-Peng Liu;Zhang-Run Xu
27 In-Situ SERS Monitoring of Intracellular H2O2 in Single Living Cells Based on Label-Free Bifunctional Fe3O4@Ag Nanoparticles 期刊论文 Yue Wang;Cheng Cheng;Ruofei Ma;Zhangrun Xu;Yukihiro Ozaki
28 Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system 期刊论文 Wen-Shu Zhang;Ya-Ning Wang;Yue Wang;Zhang-Run Xu
29 A portable multicolor aptasensor for MUC1 detection based on enzyme-mediated cascade reaction 期刊论文 Jin-Hong Sui;Yun-Yun Wei;Jin Li;Zhang-Run Xu
30 Preparation of encoded bar-like core-shell microparticles on a microfluidic chip 期刊论文 Chun-Guang Yang;Lin Cheng;Wen-Qi Ye;Dong-Hua Zheng;Zhang-Run Xu
31 A review on sensing mechanisms and strategies for telomerase activity detection 期刊论文 Danni Wang;Wanyi Xue;Xiuyan Ren;Zhangrun Xu
32 A pH-responsive colorimetric detection of human telomerase RNA based on a three-dimensional DNA amplifier 期刊论文 Danni Wang;Xiayu Zhao;Yunyun Wei;Wanyi Xue;Zhangrun Xu
33 Plasmonic Colorimetric Biosensor for Visual Detection of Telomerase Activity Based on Horseradish Peroxidase-Encapsulated Liposomes and Etching of Au Nanobipyramids 期刊论文 Danni Wang;Yingzhi Zhang;Xiayu Zhao;Zhangrun Xu
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