VSIG4通过衔接蛋白MS4a6D抑制NLRP3炎性小体活化的机制研究
81771691
2017
H1104.炎症、感染与免疫
陈永文
面上项目
教授
中国人民解放军第三军医大学
56万元
共刺激分子;巨噬细胞;MS4a6D;NLRP3炎性小体;VSIG4
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs | 期刊论文 | Xiang Qun;Feng Zeqing;Diao Bo;Tu Chao;Qiao Qinghua;Yang Han;Zhang Yi;Wang Gang;Wang Huiming;Wang Chenhui;Liu Liang;Wang Changsong;Liu Longdomg;Chen Rong;Wu Yuzhang;Chen Yongwen |
| 2 | Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection | 期刊论文 | Diao Bo;Wang Chenhui;Wang Rongshuai;Feng Zeqing;Zhang Ji;Yang Han;Tan Yingjun;Wang Huiming;Wang Changsong;Liu Liang;Liu Ying;Liu Yueping;Wang Gang;Yuan Zilin;Hou Xiaotao;Ren Liang;Wu Yuzhang;Chen Yongwen |
| 3 | 免疫共刺激分子VSIG4激活性表位肽、单克隆抗体及其制备方法和应用 | 专利 | 陈永文;吴玉章;郭晟;杨承英 |
| 4 | VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism | 期刊论文 | Li Jialin;Diao Bo;Guo Sheng;Huang Xiaoyong;Yang Chengying;Feng Zeqing;Yan Weiming;Ning Qin;Zheng Lixin;Chen Yongwen;Wu Yuzhang |
| 5 | CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation | 期刊论文 | Cui Shan;Wang Chenhui;Bai Weizhi;Li Jiao;Pan Yue;Huang Xiaoyong;Yang Han;Feng Zeqing;Xiang Qun;Fei Lei;Zheng Lixin;Huang Jian;Wu Yuzhang;Chen Yongwen |
| 6 | VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages. | 期刊论文 | Huang Xiaoyong;Feng Zeqing;Jiang Yuanzhong;Li Jiao;Xiang Qun;Guo Sheng;Yang Chengying;Fei Lei;Guo Guoning;Wu Yuzhang;Zheng Lixin;Chen Yongwen |
| 7 | Thymosin Alpha 1 Reduces the Mortality of Severe Coronavirus Disease 2019 by Restoration of Lymphocytopenia and Reversion of Exhausted T Cells | 期刊论文 | Liu Yueping;Pan Yue;Hu Zhenhong;Wu Ming;Wang Chenhui;Feng Zeqing;Mao Congzheng;Tan Yingjun;Liu Ying;Chen Li;Li Min;Wang Gang;Yuan Zilin;Diao Bo;Wu Yuzhang;Chen Yongwen |
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