线粒体质量失衡在严重创伤多器官功能损害中的作用及ER-MITO 接触调控机制
81730059
2017
H16.急重症医学
李涛
重点项目
研究员
中国人民解放军第三军医大学
295万元
创伤;线粒体质量失衡;内质网与线粒体接触点;线粒体功能障碍;多器官功能损害
2018-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The role of AQP3 in the vascular leakage of sepsis and the protective effect of Ss-31 | 期刊论文 | Jie Zhang;Ping Wang;Yue Wu;Yu Zhu;Xiao-Yong Peng;Xin-Ming Xiang;Ming-Ying Xue;Qing-Hui Li;Jun-Xia Li;Qing-Guang Yan;Liang-Ming Liu;Tao Li |
| 2 | Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2 | 期刊论文 | Chenyang Duan;Lei Kuang;Chen Hong;Xinming Xiang;Jiancang Liu;Qinghui Li;Xiaoyong Peng;Yuanqun Zhou;Hongchen Wang;Liangming Liu;Tao Li |
| 3 | Nano Parthenolide Improves Intestinal Barrier Function of Sepsis by Inhibiting Apoptosis and ROS via 5-HTR2A. | 期刊论文 | Ning-ke Guo;Han She;Lei Tan;Yuan-qun Zhou;Chun-qiong Tang;Xiao-yong Peng;Chun-hua Ma;Tao Li;Liang-ming Liu |
| 4 | Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways | 期刊论文 | Chenyang Duan;Lei Kuang;Xinming Xiang;Jie Zhang;Yu Zhu;Yue Wu;Qingguang Yan;Liangming Liu;Tao Li |
| 5 | Effects of Malate Ringer's solution on myocardial injury in sepsis and enforcement effects of TPP@PAMAM-MR | 期刊论文 | Lei Tan;Han She;Jie Zheng;Xiaoyong Peng;Ningke Guo;Bindan Zhang;Yue Sun;Chunhua Ma;Shenglian Xu;Daiqin Bao;Yuanqun Zhou;Qinghui Li;Qingxiang Mao;Liangming Liu;Yi Hu;Tao Li |
| 6 | Protective Effects of Inhibition of Mitochondrial Fission on Organ Function After Sepsis | 期刊论文 | Yu Zhu;Lei Kuang;Yue Wu;Hao-yue Deng;Han She;Yuan-qun Zhou;Jie Zhang;Liang-ming Liu;Tao Li |
| 7 | Effects of Seawater Immersion on Lethal Triad and Organ Function in Healthy and Hemorrhagic Shock Rats | 期刊论文 | Haoyue Deng;Yu Zhu;Qinghui Li;Yue Wu;Xiaoyong Peng;Liangming Liu;Tao Li |
| 8 | Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming | 期刊论文 | Han She;Yi Hu;Yuanqun Zhou;Lei Tan;Yu Zhu;Chunhua Ma;Yue Wu;Wei Chen;Li Wang;Zisen Zhang;Li Wang;Liangming Liu;Tao Li |
| 9 | 不同组织细胞线粒体数量及功能的休克敏感性研究 | 期刊论文 | 段晨阳;向鑫明;匡磊;刘良明;李涛 |
| 10 | 缺氧后活化Drp1通过偶联LRRK2影响多组织细胞线粒体功能的机制研究 | 期刊论文 | 段晨阳;向鑫明;匡磊;刘良明;李涛 |
| 11 | Endothelial Microvesicles Induce Pulmonary Vascular Leakage and Lung Injury During Sepsis | 期刊论文 | Danyang Zheng;Jie Zhang;Zisen Zhang;Lei Kuang;Yu Zhu;Yue Wu;Mingying Xue;Hongliang Zhao;Chenyang Duan;Liangming Liu;Tao Li |
| 12 | mdivi-1对急性心肌缺血小鼠心脏的保护作用 | 期刊论文 | 李清晖;吴跃;匡磊;李涛 |
| 13 | Activated Drp1-mediated mitochondrial ROS influence the gut microbiome and intestinal barrier after hemorrhagic shock | 期刊论文 | Chenyang Duan;Lei Kuang;Xinming Xiang;Jie Zhang;Yu Zhu;Yue Wu;Qingguang Yan;Liangming Liu;Tao Li |
| 14 | Mdivi-1 attenuates oxidative stress and exerts vascular protection in ischemic/hypoxic injury by a mechanism independent of Drp1 GTPase activity | 期刊论文 | Chenyang Duan;Li Wang;Jie Zhang;Xinming Xiang;Yue Wu;Zisen Zhang;Qinghui Li;Kunlun Tian;Mingying Xue;Liangming Liu;Tao Li |
| 15 | A Novel Cross-Linked Hemoglobin-Based Oxygen Carrier, YQ23, Extended the Golden Hour for Uncontrolled Hemorrhagic Shock in Rats and Miniature Pigs | 期刊论文 | Lei Kuang;Yu Zhu;Yue Wu;Kun-lun Tian;Xiao-yong Peng;Ming-ying Xue;Xin-ming Xiang;Billy Lau;Fei Chue;Liang-ming Liu;Tao Li |
| 16 | Synergetic Effect of 4-Phenylbutyric Acid in Combination with Cyclosporine A on Cardiovascular Function in Sepsis Rats via Inhibition of Endoplasmic Reticulum Stress and Mitochondrial Permeability Transition Pore Opening | 期刊论文 | Lei Kuang;Yu Zhu;Yue Wu;Xiaoyong Peng;Kunlun Tian;Liangming Liu;Tao Li |
| 17 | 环孢素A对脓毒症大鼠血管通透性的保护作用 | 期刊论文 | 吴跃;朱娱;张杰;田昆仑;彭小勇;向鑫明;刘良明;李涛 |
| 18 | Protective effects of dexmedetomidine on the vascular endothelial barrier function by inhibiting mitochondrial fission via ER/mitochondria contact | 期刊论文 | Han She;Yu Zhu;Haoyue Deng;Lei Kuang;He Fang;Zisen Zhang;Chenyang Duan;Jiaqing Ye;Jie Zhang;Liangming Liu;Yi Hu;Tao Li |
| 19 | The Landscape of Featured Metabolism-Related Genes and Imbalanced Immune Cell Subsets in Sepsis | 期刊论文 | Han She;Lei Tan;Yuanqun Zhou;Yu Zhu;Chunhua Ma;Yue Wu;Yuanlin Du;Liangming Liu;Yi Hu;Qingxiang Mao;Tao Li |
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