治疗性干预对白血病机体内正常HSC/HPC数量和功能的影响

81090413
2010
H0801.造血、造血调控与造血微环境
王健民
重大项目
教授
中国人民解放军第二军医大学
185万元
造血干/祖细胞；造血微环境；移植物抗宿主病；白血病；化疗
2011-01至2014-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB(2) Receptor Inverse Agonists and Osteoclast Inhibitors 期刊论文 程涛
2 Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro 期刊论文 Huang Chongmei;Hu Xiaoxia;Wang Libing;Lu Shuqing;Cheng Hui;Song Xianmin;Wang Jianmin;Yang Jianmin
3 急性移植物抗宿主病对骨髓CD45-Nestin+细胞数量的影响及机制初步探讨 会议论文 邹琳;高磊;钱晓迪;徐胜;胡晓霞;周虹;宋献民;王健民
4 Inducible Costimulator Gene Transduced Bone Marrow Derived Mesenchymal Stem Cells Attenuate the Severity of Acute Graft-Versus-Host Disease in a Mouse Haploidentical Model 会议论文 Yang Dan;Wang Jian-Min Sr.;Wang Li-ping;Zhou Hong
5 Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells. 期刊论文 Wu Tao;Young James S;Johnston Heather;Ni Xiong;Deng Ruishu;Racine Jeremy;Wang Miao;Wang Audrey;Todorov Ivan;Wang Jianmin;Zeng Defu
6 FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome. 期刊论文 Wang Libing;Gao Lei;Xu Sheng;Gong Shenglan;Chen Li;Lu Shuqing;Chen Jie;Qiu Huiying;Xu Xiaoqian;Ni Xiong;Song Xianmin;Zhang Weiping;Yang Jianmin;Liu Min;Hu Xiaoxia;Wang Jianmin
7 Homoharringtonine and omacetaxine for myeloid hematological malignancies 期刊论文 Shuqing Lü|Jianmin Wang|
8 High prognostic value of minimal residual disease detected by flow-cytometry-enhanced fluorescence in situ hybridization in core-binding factor acute myeloid leukemia (CBF-AML). 期刊论文 Wang Libing;Gao Lei;Xu Sheng;Gong Shenglan;Liu Min;Qiu Huiying;Xu Xiaoqian;Ni Xiong;Chen Li;Lu Shuqing;Chen Jie;Song Xianmin;Zhang Weiping;Yang Jianmin;Hu Xiaoxia;Wang Jianmin
9 Skeletal morbidity is strongly associated with poor prognosis in adult acute lymphoblastic leukemia 期刊论文 Xiaoxia Hu|Xianmin Song|Libing Wang|Jianmin Yang|Weiping Zhang|Li Chen|Shuqing Lv|Jianmin Wang|
10 Effects of ICOSLG expressed in mouse hematological neoplasm cell lines in the GVL reaction 期刊论文 Wang B.;Ma N.;Cheng H.;Zhou H.;Qiu H.;Yang J.;Wang J.
11 Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells 期刊论文 Lin J|Li LY|Gao Y|Chen Y|
12 FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome. 期刊论文 Wang Libing;Gao Lei;Xu Sheng;Gong Shenglan;Chen Li;Lu Shuqing;Chen Jie;Qiu Huiying;Xu Xiaoqian;Ni Xiong;Song Xianmin;Zhang Weiping;Yang Jianmin;Liu Min;Hu Xiaoxia;Wang Jianmin
13 Incorporation of arsenic trioxide in induction therapy improves survival of patients with newly diagnosed acute promyelocytic leukaemia. 期刊论文 Song Xianmin;Hu Xiaoxia;Lu Shuqing;Gao Lei;Chen Li;Yang Jianmin;Zhang Weiping;Wang Jianmin
14 <span style="color:black;font-family:宋体;font-size:12pt;">Inducible costimulator gene transduced bone marrow derived mesenchymal stem cells attenuate the severity of acute graft-versus-host disease in a mouse haploidentical model.</span& 期刊论文 Dan Yang|Li-Ping Wang|Hong Zhou|Hui Cheng|Xiao-Chen Bao|Sheng Xu|Wei-Ping Zhang|Jian-Min Wan|
15 细胞周期抑制剂PD033299 1对小鼠<br /> 造血干／祖细胞生物学活性的影响 期刊论文 纪庆|祁瑞哲|张丽艳|张宇|许静|袁卫平|程涛|高瀛岱|
16 Allogeneic Peripheral Blood Stem Cell Transplantation is a Promising and Safe Choice for the Treatment of Refractory/Relapsed Acute Myelogenous Leukemia, Even with a Higher Leukemia Burden 期刊论文 王健民|
17 <strong><span>Minimal Residual Disease Monitored With Fluorescence In Situ Hybridization (FISH) In CD34+CD38 Population Predicts Clinical Outcome In Core Binding Factor Acute Myeloid Leukemia (CBF-AML)</span></strong><span style 会议论文 Wang, Jian-Min|
18 Dysfunction of Bone Marrow Vascular Niche in Acute Graft-Versus-Host Disease after MHC-Haploidentical Bone Marrow Transplantation 期刊论文 Yao Yonghua;Song Xianmin;Cheng Hui;Tang Gusheng;Hu Xiaoxia;Zhou Hong;Wang Jianmin
19 急性移植物抗宿主病宿主供体来源造血干/祖细胞的功能研究 会议论文 林艳;胡晓霞;高磊;徐胜;邹琳;钱晓迪;庄晓萌;王健民
20 Expression of ICOSLG on Mouse Hematologic Neoplasm Cell Lines and Their Influence on Cytotoxicity in Allogeneic Mixed Lymphocyte Reactions 期刊论文 Wang Bin;Cheng Hui;Wang Liping;Zhou Hong;Wang Jianmin
21 Characteristics of acute myeloid leukemia with myelodysplasia-related changes: A retrospective analysis in a cohort of Chinese patients. 期刊论文 Chen, Jie|Lu, Shu-Qing|Zhang, Wei-Ping|Song, Xian-Min|
22 Allogeneic peripheral blood stem cell transplantation is a promising and safe choice for the treatment of refractory/relapsed acute myelogenous leukemia, even with a higher leukemia burden. 期刊论文 Zhang Wei-Ping;Yang Dan;Song Xian-Min;Ni Xiong;Chen Jie;Chen Li;Yang Jian-min;Zhou Hong;Cheng Hui;Liu Bao-Hai;Li Hong-Mei;Wang Jian-Min
23 Graft-versus-Host Disease Causes Broad Suppression of Hematopoietic Primitive Cells and Blocks Megakaryocyte Differentiation in a Murine Model 期刊论文 Lin Yan;Hu Xiaoxia;Cheng Hui;Pang Yakun;Wang Libing;Zou Lin;Xu Sheng;Zhuang Xiaomeng;Jiang Chuanhe;Yuan Weiping;Cheng Tao;Wang Jianmin
24 可诱导性共刺激分子转染骨髓间充质干细胞后对急性移植物抗宿主病的影响 会议论文 杨丹;王利平;包晓辰;周虹;程辉;王健民
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