白血病状态下正常造血干/祖细胞的生物学行为及调控机制研究
81090410
2010
H0801.造血、造血调控与造血微环境
程涛
重大项目
教授
中国医学科学院
1000万元
造血干/祖细胞；白血病干细胞；造血微环境
2011-01至2014-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development | 期刊论文 | Zhuan Li|Chunhong Xu|Sha Li|Yakun Pang|Guangzhou Zhang|Liping Yang|Lingling Zhu|Ming Fan|Aijia Shang|Zhenyu Ju|Lingfei Luo|Yu Lan|Yuqiang Ding|Weiping Yuan|Wei Guo|Xiao Yang|Bing Liu|Wenyan He|Dongbo Chen|Jun Wang|Fan Zhou|Yu Wang|Huayan Sun|Xianda Chen| |
| 2 | Therapeutic effects of micheliolide on a murine model of rheumatoid arthritis. | 期刊论文 | Xu Hua;Wang Jian;Wang Chijuan;Chang Guoqiang;Lin Yani;Zhang Hongju;Zhang Hairui;Li Qinghua;Pang Tianxiang |
| 3 | NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP. | 期刊论文 | Lin Yani;Chang Guoqiang;Wang Jian;Jin Weina;Wang Lihong;Li Huawen;Ma Li;Li Qinghua;Pang Tianxiang |
| 4 | <span style="font-family: ;" Roman?,?serif?;font-size:10.5pt;?="" New="" Times="">El</span><span style="color: black; font-family: ;" Roman?,?serif?;font-size:10.5pt;?="" New=" | 期刊论文 | Zhao, Xuejiao|Fang, Yong|Meng, Li|Wang, Daowen|Zhang, Hua|Gao, Qinglei|Zhou, Jianfeng|Ma, Ding| |
| 5 | Distinct sensitivity of CD8+ CD4- and CD8+ CD4+ leukemic cell subpopulations to cyclophosphamide and rapamycin in Notch1-induced T-ALL mouse model | 期刊论文 | Zhang Y.;Hua C.;Cheng H.;Wang W.;Hao S.;Xu J.;Wang X.;Gao Y.;Zhu X.;Cheng T.;Yuan W. |
| 6 | Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells | 期刊论文 | Wu T|Young JS|Johnston H|Wang A|Todorov I|Wang J|Zeng D| |
| 7 | A systematic comparison of the anti-tumoural activity and toxicity of the three Adv-TKs. | 期刊论文 | Gao Qinglei;Chen Caihong;Ji Teng;Wu Peng;Han Zhiqiang;Fang Haiyan;Li Fei;Liu Yi;Hu Wencheng;Gong Danni;Zhang Zeyu;Wang Shixuan;Zhou Jianfeng;Ma Ding |
| 8 | Identification of functional cooperative mutations of SETD2 in human acute leukemia | 期刊论文 | Zhu Xiaofan;He Fuhong;Zeng Huimin;Ling Shaoping;Chen Aili;Wang Yaqin;Yan Xiaomei;Wei Wei;Pang Yakun;Cheng Hui;Hua Chunlan;Zhang Yue;Yang Xuejing;Lu Xin;Cao Lihua;Hao Lingtong;Dong Lili;Zou Wei;Wu Jun;Li Xia;Zheng Si;Yan Jin;Zhou Jing;Zhang Lixia;Mi Shuangli;Wang Xiaojuan;Zhang Li;Zou Yao;Chen Yumei;Geng Zhe;Wang Jianmin;Zhou Jianfeng;Liu Xin;Wang Jianxiang;Yuan Weiping;Huang Gang;Cheng Tao;Wang Qian fei |
| 9 | Inducible costimulator gene transduced bone marrow derived mesenchymal stem cells attenuate the severity of acute graft-versus-host disease in mouse models. | 期刊论文 | Yang Dan;Wang Li-Ping;Zhou Hong;Cheng Hui;Bao Xiao-Chen;Xu Sheng;Zhang Wei-Ping;Wang Jian-Min |
| 10 | Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. | 期刊论文 | Yang Peng;Myint Kyaw-Zeyar;Tong Qin;Feng Rentian;Cao Haiping;Almehizia Abdulrahman A;Alqarni Mohammed Hamed;Wang Lirong;Bartlow Patrick;Gao Yingdai;Gertsch Jurg;Teramachi Jumpei;Kurihara Noriyoshi;Roodman Garson David;Cheng Tao;Xie Xiang-Qun |
| 11 | 组蛋白甲基转移酶在造血干细胞调控和白血病发生中的作用 | 期刊论文 | 王晓娟;袁卫平;程涛 |
| 12 | FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome. | 期刊论文 | Wang Libing;Gao Lei;Xu Sheng;Gong Shenglan;Chen Li;Lu Shuqing;Chen Jie;Qiu Huiying;Xu Xiaoqian;Ni Xiong;Song Xianmin;Zhang Weiping;Yang Jianmin;Liu Min;Hu Xiaoxia;Wang Jianmin |
| 13 | The Regulation of Normal and Leukemic Hematopoietic Stem Cells by Niches | 期刊论文 | 诸江| |
| 14 | FISH+CD34+CD38- cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome | 期刊论文 | Wang L;Gao L;Xu S;Gong S;Chen L;Lü S;Chen J;Qiu H;Xu X;Ni X;Song X;Zhang W;Yang J;Liu M;Hu X;Wang J |
| 15 | NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP. | 期刊论文 | Lin Yani;Wang Jian;Jin Weina;Wang Lihong;Li Huawen;Ma Li;Li Qinghua;Pang Tianxiang |
| 16 | Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing | 期刊论文 | Zhang Zhaojun;Jia Haibo;Zhang Qian;Wan Yang;Zhou Yang;Jia Qiong;Zhang Wanguang;Yuan Weiping;Cheng Tao;Zhu Xiaofan;Fang Xiangdong |
| 17 | Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer. | 期刊论文 | Han Zhiqiang();Wang Xiaoli;Ma Liang;Chen Lijuan;Xiao Min;Huang Liang;Cao Yang;Bai Jian;Ma Ding;Zhou Jianfeng;Hong Zhenya |
| 18 | Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction | 期刊论文 | Wang Ji-Ying;Yu Pei;Chen Shuying;Xing Haiyan;Chen Yirui;Wang Min;Tang Kejing;Tian Zheng;Rao Qing;Wang Jianxiang |
| 19 | Skeletal morbidity is strongly associated with poor prognosis in adult acute lymphoblastic leukemia. | 期刊论文 | Hu Xiaoxia;Song Xianmin;Wang Libing;Yang Jianmin;Zhang Weiping;Chen Li;Lv Shuqing;Wang Jianmin |
| 20 | 体外培养单个造血干细胞实验方法的建立 | 期刊论文 | 李乔;纪庆;王金宏;许静;田晨;程辉;刘延风;张娜;程涛;高瀛岱 |
| 21 | miR-9 regulation of BRCA1 and ovarian cancer sensitivity to cisplatin and PARP inhibition. | 期刊论文 | Sun Chaoyang;Li Na;Yang Zongyuan;Zhou Bo;He Yang;Weng Danhui;Fang Yong;Wu Peng;Chen Pingbo;Yang Xiaokui;Ma Ding;Zhou Jianfeng;Chen Gang |
| 22 | Rictor/mammalian target of rapamycin 2 regulates the development of notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3. | 期刊论文 | Hua Chunlan;Guo Huidong;Bu Jiachen;Zhou Mi;Cheng Hui;He Fuhong;Wang Jinhong;Wang Xiaomin;Zhang Yinchi;Wang Qianfei;Zhou Jianfeng;Cheng Tao;Xu Mingjiang;Yuan Weiping |
| 23 | Neutrophil gelatinase–associated lipocalin regulates intracellular accumulation of Rh123 in cancer cells | 期刊论文 | 庞天翔| |
| 24 | CUEDC2 sensitizes chronic myeloid leukemic cells to imatinib treatment | 期刊论文 | Jiang Li;Liu Jian-Feng;Sun Dongxiao;Ma Peipei;Ding Xiangdong;Yu Ying;Zhang Qin |
| 25 | Dysfunction of Bone Marrow Vascular Niche in Acute Graft-Versus-Host Disease after MHC-Haploidentical Bone Marrow Transplantation | 期刊论文 | Yao Yonghua;Song Xianmin;Cheng Hui;Tang Gusheng;Hu Xiaoxia;Zhou Hong;Wang Jianmin |
| 26 | Characteristics of acute myeloid leukemia with myelodysplasia-related changes: A retrospective analysis in a cohort of Chinese patients | 期刊论文 | Xu Xiao-Qian;Wang Jian-Min;Gao Lei;Qiu Hui-Ying;Chen Li;Jia Lin;Hu Xiao-Xia;Yang Jian-Min;Ni Xiong;Chen Jie;Lv Shu-Qing;Zhang Wei-Ping;Song Xian-Min |
| 27 | Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells. | 期刊论文 | Zhang Quan;Lu Yaxin;Ding Yahui;Zhai Jiadai;Ji Qing;Ma Weiwei;Yang Ming;Fan Hongxia;Long Jing;Tong Zhongsheng;Shi Yehui;Jia Yongsheng;Han Bin;Zhang Wenpeng;Qiu Chuanjiang;Ma Xiaoyan;Li Qiuying;Shi Qianqian;Zhang Haoliang;Li Dongmei;Zhang Jing;Lin Jianping;Li Lu-Yuan;Gao Yingdai;Chen Yue |
| 28 | The impact of tumor microenvironments on stem cells | 期刊论文 | Wangl Lina;Cheng tao;Zheng Guoguang |
| 29 | Purinergic P2Y(1)(4) receptor modulates stress-induced hematopoietic stem/progenitor cell senescence. | 期刊论文 | Cho Joonseok;Yusuf Rushdia;Kook Sungho;Attar Eyal;Lee Dongjun;Park Baehang;Cheng Tao;Scadden David T;Lee Byeong Chel |
| 30 | Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen. | 期刊论文 | Ma Shihui;Shi Yingxu;Pang Yakun;Dong Fang;Cheng Hui;Hao Sha;Xu Jing;Zhu Xiaofan;Yuan Weiping;Cheng Tao;Zheng Guoguang |
| 31 | Abnormal immunophenotype provides a key diagnostic marker: a report of 29 cases of de novo aggressive natural killer cell leukemia. | 期刊论文 | Li Chunrui;Tian Ye;Wang Jue;Zhu Li;Huang Liang;Wang Na;Xu Danmei;Cao Yang;Li Jianyong;Zhou Jianfeng |
| 32 | Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro | 期刊论文 | Huang Chongmei;Hu Xiaoxia;Wang Libing;Lu Shuqing;Cheng Hui;Song Xianmin;Wang Jianmin;Yang Jianmin |
| 33 | Homoharringtonine and omacetaxine for myeloid hematological malignancies | 期刊论文 | Shuqing Lü|Jianmin Wang| |
| 34 | p18~(INK4C)调控小鼠T细胞的发育及功能 | 期刊论文 | 郝莎;董芳;王娅婕;程辉;袁卫平;程涛 |
| 35 | <em>Mixed Lineage Leukemia 5 (MLL5) Protein Regulates Cell Cycle Progression and E2F1-responsive Gene Expression via Association with Host Cell Factor-1 (HCF-1)Mixed Lineage Leukemia 5 (MLL5) Protein Regulates Cell Cycle Progression and E2F1-respons | 期刊论文 | xiaoling Wan|Feng Zhang|Xiaodan Ding|Chuangui Wang|Sidong Xiong|Zhen Wang|Jinduo Yuan|Qiang Li|Yan Zhang| |
| 36 | Down-regulation of the P-glycoprotein relevant for multidrug resistance by intracellular acidification through the crosstalk of MAPK signaling pathways. | 期刊论文 | Jin Weina;Lu Ying;Li Qinghua;Wang Jian;Zhang Hongju;Chang Guoqiang;Lin Yani;Pang Tianxiang |
| 37 | Oncogene iASPP enhances self-renewal of hematopoietic stem cells and facilitates their resistance to chemotherapy and irradiation. | 期刊论文 | Peng Leiwen;Jia Yujiao;Rao Qing;Xing Haiyan;Huai Lei;Yu Pei;Chen Yirui;Wang Cuicui;Wang Min;Mi Yingchang;Wang Jianxiang |
| 38 | <strong>PI3K/AKT/mTOR信号通路在造血干细胞中作用的研究进展</strong> | 期刊论文 | 张英驰|张英驰|程涛|程涛|袁卫平|袁卫平| |
| 39 | CIAPIN1 targets Na+/H+ exchanger 1 to mediate K562 chronic myeloid leukemia cells' differentiation via ERK1/2 signaling pathway. | 期刊论文 | Zhang, Hairui|Wang, Qi|Wang, Chijuan|Zhang, Hongju|Lin, Yani|Ru, Yongxin|Liang, Haoyue|Li, Qinghua|Pang, Tianxiang| |
| 40 | Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment | 期刊论文 | Tian Chen;Zheng Guoguang;Cao Zhipan;Li Qiao;Ju Zhenyu;Wang Jinhong;Yuan Weiping;Cheng Tao |
| 41 | An Opposite Effect of the CDK Inhibitor, p18(INK4c) on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells | 期刊论文 | Li Y.;Pal R.;Sung L. Y.;Feng H.;Miao W.;Cheng S. Y.;Tian C.;Cheng T. |
| 42 | Transcriptome analysis of the zebrafish model of Diamond-Blackfan anemia from RPS19 deficiency via p53-dependent and -independent pathways | 期刊论文 | Jia Q.;Zhang Q.;Zhang Z.;Wang Y.;Zhang W.;Zhou Y.;Wan Y.;Cheng T.;Zhu X.;Fang X.;Yuan W.;Jia H. |
| 43 | 细胞周期抑制剂PD0332991对小鼠造血干/祖细胞生物学活性的影响 | 期刊论文 | 纪庆;祁瑞哲;张丽艳;张宇;许静;袁卫平;程涛;高瀛岱 |
| 44 | SIL-TAL1 rearrangement is related with poor outcome: a study from a Chinese institution | 期刊论文 | Yang, Y.|Zhou, S.|Xiong, J.|He, J.|Jiang, L.|Li, C.|Xu, D.|Huang, L.|Zhou, J.| |
| 45 | DAPT对小鼠造血干细胞生物活性的影响 | 期刊论文 | 张娜;张丽艳;张燕;纪庆;王金宏;祁瑞哲;许静;袁卫平;程涛;高瀛岱 |
| 46 | Systematic transcriptome analysis of the zebrafish model of diamond-blackfan anemia induced by RPS24 deficiency | 期刊论文 | Song Binfeng();Zhang Qian;Zhang Zhaojun;Wan Yang;Jia Qiong;Wang Xiaomin;Zhu Xiaofan;Leung Anskar Yu-Hung;Cheng Tao;Fang Xiangdong();Yuan Weiping;Jia Haibo |
| 47 | PI3K/AKT信号通路在急性白血病中调控机制的初步研究 | 期刊论文 | 王伟丽;张英弛;曾慧敏;华春兰;魏蔚;许静;竺晓凡;程涛;袁卫平 |
| 48 | Effects of ICOSLG expressed in mouse hematological neoplasm cell lines in the GVL reaction | 期刊论文 | Wang B.;Ma N.;Cheng H.;Zhou H.;Qiu H.;Yang J.;Wang J. |
| 49 | IFN-gamma promotes graft-versus-leukemia effects without directly interacting with leukemia cells in mice after allogeneic hematopoietic cell transplantation. | 期刊论文 | Yang Yanping;Wang Hui;Yu Hui;Yeap Beow Yong;Liang Tingting;Wang Guanjun;Cheng Tao;Yang Yong-Guang |
| 50 | CUEDC2 sensitizes chronic myeloid leukemic cells to imatinib treatment | 期刊论文 | Jiang Li;Liu Jian-Feng;Sun Dongxiao;Ma Peipei;Ding Xiangdong;Yu Ying;Zhang Qin |
| 51 | 非基因整合建立人诱导多能性干细胞方法的优化研究 | 期刊论文 | 刘淑平();李彦欣;许静;顾海慧;张鸿雁;梁昊岳;刘汉芝;张孝兵;程涛;袁卫平 |
| 52 | Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. | 期刊论文 | Lan Yu;He Wenyan;Li Zhuan;Wang Yu;Wang Jun;Gao Jiao;Wang Weili;Cheng Tao;Liu Bing;Yang Xiao |
| 53 | Graft-versus-host disease causes broad suppression of hematopoietic primitive cells and blocks megakaryocyte differentiation in a murine model. | 期刊论文 | Lin Yan;Hu Xiaoxia;Cheng Hui;Pang Yakun;Wang Libing;Zou Lin;Xu Sheng;Zhuang Xiaomeng;Jiang Chuanhe;Yuan Weiping;Cheng Tao;Wang Jianmin |
| 54 | 抑制Larp4b表达不影响小鼠Lin~-造血细胞集落形成能力 | 期刊论文 | 王晓娟;庞雅坤;程辉;董芳;梁昊岳;张英驰;汪晓敏;许静;程涛;袁卫平 |
| 55 | <span style="font-family:"Times New Roman","serif";font-size:10.5pt;">p18<sup>INK4C</sup> </span><span style="font-family:"Times New Roman"," | 期刊论文 | Ji Qing|Bartlow Patrick|Bartlow Patrick|Ding Yahui|Ding Yahui|Yuan Weiping|Yuan Weiping|Cheng,Tao|Cheng,Tao| |
| 56 | Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice. | 期刊论文 | Yao Yunyi;Liu Senyan;Wang Yue;Yuan Weiping;Ding Xinxin;Cheng Tao;Shen Qin;Gu Jun |
| 57 | RIG-I Modulates Src-Mediated AKT Activation to Restrain Leukemic Stemness | 期刊论文 | Li Xian Yang;Jiang Lin Jia;Chen Lei;Ding Meng Lei;Guo He Zhou;Zhang Wu;Zhang Hong Xin;Ma Xiao Dan;Liu Xiang Zhen;Xi Xiao Dong;Chen Sai Juan;Chen Zhu;Zhu Jiang |
| 58 | Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging. | 期刊论文 | Ju Zhenyu;Zhang Junling;Gao Yingdai;Cheng Tao |
| 59 | The regulation of normal and leukemic hematopoietic stem cells by niches. | 期刊论文 | Huang, Meng-Meng|Zhu, Jiang| |
| 60 | 血病细胞中共表达P2X7受体和Notch1胞内区 | 期刊论文 | 冯丽|杨骁|廖金凤|陈莎燕|冯文利|林永敏|任倩|郑国光| |
| 61 | Puma表达下调对人脐血CD34~+造血细胞抗放射作用的初步研究 | 期刊论文 | 赵蕾();张鸿雁;庞雅坤;顾海慧;许静;袁卫平;程涛 |
| 62 | Hematopoietic Stem Cell Regeneration Enhanced by Ectopic Expression of ROS-detoxifying Enzymes in Transplant Mice | 期刊论文 | Miao Weimin;XuFeng Richard;Park Moo-Rim;Gu Haihui;Hu Linping;Kang Jin Wook;Ma Shihui;Liang Paulina H.;Li Yanxin;Cheng Haizi;Yu Hui;Epperly Michael;Greenberger Joel;Cheng Tao |
| 63 | 范可尼贫血肿瘤相关通路的基因集富集分析 | 期刊论文 | 周全全|CHENG Tao|王晓娟|竺晓凡|袁卫平|程涛|ZHOU Qua-quan|WANG Xiao-juan|ZHU Xiao-fan|YUAN Wei-ping| |
| 64 | Rictor is required for early B cell development in bone marrow | 期刊论文 | Yingchi Zhang;Tianyuan Hu;Chunlan Hua;Jie Gu;Sha Hao;Haoyue Liang;Xiaomin Wang;Weili Wang;Jing Xu;Tao Cheng;Weiping Yuan |
| 65 | RIG-I modulates Src-mediated AKT activation to restrain leukemic stemness. | 期刊论文 | Li Xian-Yang;Jiang Lin-Jia;Chen Lei;Ding Meng-Lei;Guo He-Zhou;Zhang Wu;Zhang Hong-Xin;Ma Xiao-Dan;Liu Xiang-Zhen;Xi Xiao-Dong;Chen Sai-Juan;Chen Zhu;Zhu Jiang |
| 66 | CD44 targets Na(+)/H(+) exchanger 1 to mediate MDA-MB-231 cells' metastasis via the regulation of ERK1/2. | 期刊论文 | Zhang, H|Zhang, Y|Wang, C|Xu, H|Zhang, H|Lin, Y|Ma, L|Li, Q|Pang, T| |
| 67 | Rheb过表达在白血病细胞株HL60和K562中作用研究 | 期刊论文 | 徐乔竹|汪晓敏|王放放|高亚男|张英驰|鞠振宇|程涛|袁卫平|刘汉芝| |
| 68 | Reversal of Imatinib resistance in BCR-ABL-positive leukemia after inhibition of the Na+/H+ exchanger. | 期刊论文 | Jin Weina;Li Qinghua;Lin Yani;Lu Ying;Li Huawen;Wang Lihong;Hu Ronghua;Ma Li;Wang Jianxiang;Pang Tianxiang |
| 69 | Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB(2) Receptor Inverse Agonists and Osteoclast Inhibitors | 期刊论文 | 程涛 |
| 70 | Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells. | 期刊论文 | Wu Tao;Young James S;Johnston Heather;Ni Xiong;Deng Ruishu;Racine Jeremy;Wang Miao;Wang Audrey;Todorov Ivan;Wang Jianmin;Zeng Defu |
| 71 | Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment | 期刊论文 | Tian Chen;Zheng Guoguang;Cao Zhipan;Li Qiao;Ju Zhenyu;Wang Jinhong;Yuan Weiping;Cheng Tao |
| 72 | 内皮和造血系统特异性敲除Rictor基因对胎肝造血的影响 | 期刊论文 | 穆晓环();王伟丽;赵云泽;倪艳丽;李专;顾洁;张丽艳;汪晓敏;程涛;刘汉芝;袁卫平;刘兵 |
| 73 | An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic stem cells | 期刊论文 | XuFeng, R.|Yuan, Y.|Yuan, Y.|Zhang, P.|Zhang, P.|Smith, C. A.|Smith, C. A.|Cheng, T.|Cheng, T.| |
| 74 | Stem Cell Science On the Rise in China | 期刊论文 | Yuan Weiping;Sipp Douglas;Wang Zack Z.;Deng Hongkui;Pei Duanqing;Zhou Qi;Cheng Tao |
| 75 | Inhibition of K562 leukemia angiogenesis and growth by selective Na<sup>+</sup>/H<sup>+</sup> exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF | 期刊论文 | Guoqiang Chang|Jian Wang|Weina Jin|Lihong Wang|Yani Lin|Huawen Li|Li Ma|Qinghua Li|Tianxiang Pang| |
| 76 | <strong>mTOR信号通路在造血及其它系统衰老中作用的研究进展</strong> | 期刊论文 | 华春兰|华春兰|程涛|程涛|袁卫平|袁卫平| |
| 77 | CD44 targets Wnt/beta-catenin pathway to mediate the proliferation of K562 cells. | 期刊论文 | Chang Guoqiang;Zhang Hongju;Wang Jian;Zhang Yujuan;Xu Hua;Wang Chijuan;Zhang Hairui;Ma Li;Li Qinghua;Pang Tianxiang |
| 78 | 抑制Larp4b表达不促进小鼠Lin-造血细胞克隆形成能力 | 期刊论文 | 庞雅坤|程辉|董芳|梁昊岳|张英驰|汪晓敏|许静|程涛|袁卫平| |
| 79 | Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction. | 期刊论文 | Wang Ji-Ying;Yu Pei;Chen Shuying;Xing Haiyan;Chen Yirui;Wang Min;Tang Kejing;Tian Zheng;Rao Qing;Wang Jianxiang |
| 80 | High prognostic value of minimal residual disease detected by flow-cytometry-enhanced fluorescence in situ hybridization in core-binding factor acute myeloid leukemia (CBF-AML). | 期刊论文 | Wang Libing;Gao Lei;Xu Sheng;Gong Shenglan;Liu Min;Qiu Huiying;Xu Xiaoqian;Ni Xiong;Chen Li;Lu Shuqing;Chen Jie;Song Xianmin;Zhang Weiping;Yang Jianmin;Hu Xiaoxia;Wang Jianmin |
| 81 | Na+/H+ exchanger 1 inhibition contributes to K562 leukaemic cell differentiation. | 期刊论文 | Jin Weina;Li Qinghua;Wang Jian;Chang Guoqiang;Lin Yani;Li Huawen;Wang Lihong;Gao Wei;Pang Tianxiang |
| 82 | Identification of functional cooperative mutations of SETD2 in human acute leukemia. | 期刊论文 | Zhu Xiaofan;He Fuhong;Zeng Huimin;Ling Shaoping;Chen Aili;Wang Yaqin;Yan Xiaomei;Wei Wei;Pang Yakun;Cheng Hui;Hua Chunlan;Zhang Yue;Yang Xuejing;Lu Xin;Cao Lihua;Hao Lingtong;Dong Lili;Zou Wei;Wu Jun;Li Xia;Zheng Si;Yan Jin;Zhou Jing;Zhang Lixia;Mi Shuangli;Wang Xiaojuan;Zhang Li;Zou Yao;Chen Yumei;Geng Zhe;Wang Jianmin;Zhou Jianfeng... |
| 83 | Skeletal morbidity is strongly associated with poor prognosis in adult acute lymphoblastic leukemia | 期刊论文 | Xiaoxia Hu|Xianmin Song|Libing Wang|Jianmin Yang|Weiping Zhang|Li Chen|Shuqing Lv|Jianmin Wang| |
| 84 | The p53-PUMA axis suppresses iPSC generation | 期刊论文 | Yanxin Li;Haizhong Feng;Haihui Gu;Dale W. Lewis;Youzhong Yuan;Lei Zhang;Hui Yu;Peng Zhang;Haizi Cheng;Weimin Miao;Weiping Yuan;Shi-Yuan Cheng;Susanne M. Gollin;Tao Cheng |
| 85 | Systematic characterization of small RNAome during zebrafish early developmental stages. | 期刊论文 | Yao Yuangen;Ma Lili;Jia Qiong;Deng Wankun;Liu Zexian;Zhang Yuanwei;Ren Jian;Xue Yu;Jia Haibo;Yang Qing |
| 86 | Functional expression of P2X family receptors in macrophages is affected by microenvironment in mouse T cell acute lymphoblastic leukemia. | 期刊论文 | Chen Shayan;Feng Wenli;Yang Xiao;Yang Wanzhu;Ru Yongxin;Liao Jinfeng;Wang Lina;Lin Yongmin;Ren Qian;Zheng Guoguang |
| 87 | Incorporation of arsenic trioxide in induction therapy improves survival of patients with newly diagnosed acute promyelocytic leukaemia. | 期刊论文 | Song Xianmin;Hu Xiaoxia;Lu Shuqing;Gao Lei;Chen Li;Yang Jianmin;Zhang Weiping;Wang Jianmin |
| 88 | Arsenic disulfide synergizes with the phosphoinositide 3-kinase inhibitor PI-103 to eradicate acute myeloid leukemia stem cells by inducing differentiation. | 期刊论文 | Hong Zhenya;Xiao Min;Yang Yang;Han Zhiqiang;Cao Yang;Li Chunrui;Wu Ying;Gong Quan;Zhou Xiaoxi;Xu Danmei;Meng Li;Ma Ding;Zhou Jianfeng |
| 89 | Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice | 期刊论文 | Yao Yunyi;Liu Senyan;Wang Yue;Yuan Weiping;Ding Xinxin;Cheng Tao;Shen Qin;Gu Jun |
| 90 | Mll2 controls cardiac lineage differentiation of mouse embryonic stem cells by promoting H3K4me3 deposition at cardiac-specific genes. | 期刊论文 | Wan Xiaoling;Liu Lulu;Ding Xiaodan;Zhou Peipei;Yuan Xiujie;Zhou Zhongwen;Hu Ping;Zhou Hong;Li Qiang;Zhang Shenghai;Xiong Sidong;Zhang Yan |
| 91 | Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing | 期刊论文 | Zhang Zhaojun;Jia Haibo;Zhang Qian;Wan Yang;Zhou Yang;Jia Qiong;Zhang Wanguang;Yuan Weiping;Cheng Tao;Zhu Xiaofan;Fang Xiangdong |
| 92 | Allogeneic Peripheral Blood Stem Cell Transplantation is a Promising and Safe Choice for the Treatment of Refractory/Relapsed Acute Myelogenous Leukemia, Even with a Higher Leukemia Burden | 期刊论文 | Ni X.|Chen J.|Chen L.|Yang J.-M.|Zhou H.|Cheng H.|Liu B.-H.|Li H.-M.|Wang J.-M.| |
| 93 | The balance of positive and negative effects of TGF-beta signaling regulates the development of hematopoietic and endothelial progenitors in human pluripotent stem cells | 期刊论文 | Bai H.;Xie Y. L.;Gao Y. X.;Cheng T.;Wang Z. Z. |
| 94 | Systematic characterization of small RNAome during zebrafish early developmental stages | 期刊论文 | Yao Yuangen;Ma Lili;Jia Qiong;Deng Wankun;Liu Zexian;Zhang Yuanwei;Ren Jian;Xue Yu;Jia Haibo;Yang Qing |
| 95 | 造血系统常用Cre转基因小鼠及其应用 | 期刊论文 | 彭路芸;程涛;袁卫平 |
| 96 | Na+/H+ exchanger 1 inhibition contributes to K562 leukemic cell differentiation | 期刊论文 | 庞天翔| |
| 97 | Skeletal morbidity is strongly associated with poor prognosis in adult acute lymphoblastic leukemia | 期刊论文 | Xiaoxia Hu|Xianmin Song|Libing Wang|Jianmin Yang|Weiping Zhang|Li Chen|Shuqing Lv|Jianmin Wang| |
| 98 | Decreased intracellular pH induced by cariporide differentially contributes to human umbilical cord-derived mesenchymal stem cells differentiation. | 期刊论文 | Gao Wei;Zhang Hairui;Chang Guoqiang;Xie Zhenqing;Wang Hanyu;Ma Li;Han Zhongchao;Li Qinghua;Pang Tianxiang |
| 99 | mTORC2功能及其在血液肿瘤中作用的研究进展 | 期刊论文 | 郭惠东;程涛;袁卫平 |
| 100 | <strong>NKT 细胞与移植物抗宿主病</strong> | 期刊论文 | 赵蕾|赵蕾|郝莎|郝莎|袁卫平|袁卫平|程涛|程涛| |
| 101 | Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells | 期刊论文 | Yanfeng Liu;Hui Cheng;Shuai Gao;Xin Lu;Fuhong He;Linping Hu;Di Hou;Zhengyong Zou;Yanxin Li;Hongyan Zhang;Jing Xu;Lan Kang;Qian-Fei Wang;Weiping Yuan;Shaorong Gao;Tao Cheng |
| 102 | Rheb过表达在白血病细胞株HL-60和K562中的作用 | 期刊论文 | 徐乔竹;汪晓敏;王放放;高亚男;张英驰;鞠振宇;程涛;袁卫平;刘汉芝 |
| 103 | Cariporide sensitizes leukemic cells to tumor necrosis factor related apoptosis-inducing ligand by up-regulation of death receptor 5 via endoplasmic reticulum stress-CCAAT/enhancer binding protein homologous protein dependent mechanism. | 期刊论文 | Li Huawen;Chang Guoqiang;Wang Jian;Wang Lihong;Jin Weina;Lin Yani;Yan Yan;Wang Ruojun;Gao Wei;Ma Li;Li Qinghua;Pang Tianxiang |
| 104 | Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells | 期刊论文 | Lin J|Li LY|Gao Y|Chen Y| |
| 105 | <strong>内皮细胞微环境对造血干细胞的调控</strong> | 期刊论文 | 顾欣|顾欣|袁卫平|袁卫平|程涛|程涛| |
| 106 | C/EBP ζ targets to neutrophil gelatinase-associated lipocalin (NGAL) as a repressor for metastasis of MDA-MB-231 cells | 期刊论文 | Wang L.;Li H.;Wang J.;Gao W.;Lin Y.;Jin W.;Chang G.;Wang R.;Li Q.;Ma L.;Pang T. |
| 107 | TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy. | 期刊论文 | Hu Zheng;Ding Wencheng;Zhu Da;Yu Lan;Jiang Xiaohui;Wang Xiaoli;Zhang Changlin;Wang Liming;Ji Teng;Liu Dan;He Dan;Xia Xi;Zhu Tao;Wei Juncheng;Wu Peng;Wang Changyu;Xi Ling;Gao Qinglei;Chen Gang;Liu Rong;Li Kezhen;Li Shuang;Wang Shixuan;Zhou Jianfeng;Ma Ding;Wang Hui |
| 108 | <span style="font-family: ;" Roman?,?serif?;font-size:10.5pt;?="" New="" Times="">The impact of tumor microenvironments on stem cells</span> | 期刊论文 | Wangl Lina|Cheng tao|Zheng Guoguang| |
| 109 | 小鼠造血各系细胞中氧化还原酶差异表达的研究 | 期刊论文 | 张燕;张娜;庞雅坤;程辉;刘灵;王金宏;顾洁;许静;缪为民;顾军;李妍涵;程涛;袁卫平 |
| 110 | Suppression of Cytochrome P450 Reductase Enhances Long-Term Hematopoietic Stem Cell Repopulation Efficiency in Mice | 期刊论文 | Zhang Yan;Dong Fang;Zhang Na;Cheng Hui;Pang Yakun;Wang Xiaomin;Xu Jing;Ding Xinxin;Cheng Tao;Gu Jun;Yuan Weiping |
| 111 | Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). | 期刊论文 | Zhou Peipei;Wang Zhilong;Yuan Xiujie;Zhou Cuihong;Liu Lulu;Wan Xiaoling;Zhang Feng;Ding Xiaodan;Wang Chuangui;Xiong Sidong;Wang Zhen;Yuan Jinduo;Li Qiang;Zhang Yan |
| 112 | Allogeneic peripheral blood stem cell transplantation is a promising and safe choice for the treatment of refractory/relapsed acute myelogenous leukemia, even with a higher leukemia burden | 期刊论文 | Zhang WP|Yang D|Song XM|Ni X|Li HM|Wang JM| |
| 113 | <strong><span style="line-height: 115%; font-family: ;" roman?,?serif?;font-size:12pt;?="" new="" times="">Myeloid cell-derived reactive oxygen species externally regulate </span><span style=&qu | 期刊论文 | Haiyan Zhu|Li Chai|Li Chai|Leslie E. Silberstein|Leslie E. Silberstein|Tao Cheng|Tao Cheng|Hongbo R. Luo|Hongbo R. Luo| |
| 114 | Antioxidant N-acetyl-l-cysteine increases engraftment of human hematopoietic stem cells in immune-deficient mice. | 期刊论文 | Hu Linping;Cheng Hui;Gao Yingdai;Shi Ming;Liu Yanfeng;Hu Zheng;Xu Jing;Qiu Lugui;Yuan Weiping;Leung Anskar Yu-Hung;Yang Yong-Guang;Cheng Tao |
| 115 | SIL-TAL1 rearrangement is related with poor outcome: a study from a Chinese institution. | 期刊论文 | Wang Di;Zhu Guangrong;Wang Na;Zhou Xiaoxi;Yang Yunfan;Zhou Shiqiu;Xiong Jie;He Jing;Jiang Lijun;Li Chunrui;Xu Danmei;Huang Liang;Zhou Jianfeng |
| 116 | Neutrophil gelatinase-associated lipocalin regulates intracellular accumulation of Rh123 in cancer cells. | 期刊论文 | Wang Li-Hong;Chang Guo-Qiang;Zhang Hong-Ju;Wang Jian;Lin Ya-Ni;Jin Wei-Na;Li Hua-Wen;Gao Wei;Wang Ruo-Jun;Li Qing-Hua;Pang Tian-Xiang |
| 117 | Stem Cell Science On the Rise in China | 期刊论文 | Yuan Weiping;Sipp Douglas;Wang Zack Z.;Deng Hongkui;Pei Duanqing;Zhou Qi;Cheng Tao |
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