Cofilin线粒体转位通过影响线粒体分裂调控细胞凋亡的分子机制

31571425
2015
C0705.细胞衰老、死亡及自噬
高宁
面上项目
教授
中国人民解放军第三军医大学
65万元
Cofilin;细胞凋亡;线粒体分裂
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 中国医院协会医院科技创新奖一等奖 奖励 高宁
2 千金藤素协同多柔比星逆转K562/ADR耐药的分子机制研究 期刊论文 姜秀星;傅若秋;高宁
3 Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. 期刊论文 Hong-Wei Zhang;Jin-Jiao Hu;Ruo-Qiu Fu;Xin Liu;Yan-Hao Zhang;Jing Li;Lei Liu;Yu-Nong Li;Qin Deng;Qing-Song Luo;Qin Ouyang;Ning Gao
4 Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage 期刊论文 Yunong Li;Xiuxing Jiang;Yanhao Zhang;Ziyi Gao;Yanxia Liu;Jinjiao Hu;Xiaoye Hu;Lirong Li;Jingshan Shi;Ning Gao
5 A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosomelysosome fusion through upregulation of BNIP3 期刊论文 Ruoqiu Fu;Qin Deng;Hongwei Zhang;Xiaoye Hu;Yunong Li;Yanxia Liu;Jinjiao Hu;Qingsong Luo;Yanhao Zhang;Xiuxing Jiang;Lirong Li;Chong Yang;Ning Gao
6 千金藤素对乳腺癌细胞MDA-MB-231自噬降解的影响 期刊论文 邓琴;傅若秋;高宁
7 Mitochondrial fission and mitophagy depend on cofilin-mediated actin depolymerization activity at the mitochondrial fission site. 期刊论文 Guobing Li;Hongwei Zhang;Ruoqiu Fu;Xiaoye Hu;Lei Liu;Yunong Li;Yanxia Liu;Jinjiao Hu;Qin Deng;Qingsong Luo;Rong Zhang;Ning Gao
8 8-姜酚抑制乳腺癌细胞增殖的分子机制研究.第三军医大学学报.2019, 41(5): 406-414.通讯作者 期刊论文 杨崇;傅若秋;高宁
9 Ars2 promotes cell proliferation and tumorigenicity in glioblastoma through regulating miR-6798-3p. 期刊论文 Yibiao Chen;Xiaoye Hu;Yunong Li;Hongwei Zhang;Ruoqiu Fu;Yanxia Liu;Jinjiao Hu;Qin Deng;Qingsong Luo;Dunke Zhang;Ning Gao;Hongjuan Cui
10 Downregulation of MYO1C mediated by cepharanthine inhibits autophagosome-lysosome fusion through blockade of the F-actin network. 期刊论文 Yanhao Zhang;Xiuxing Jiang;Qin Deng;Ziyi Gao;Xiangyu Tang;Ruoqiu Fu;Jinjiao Hu;Yunong Li;Lirong Li;Ning Gao
11 长链非编码RNALINCO1140对急性髓系白血病U937细胞增殖及周期的影响 期刊论文 骆青松;胡晓烨;朱垚;高宁
12 异鼠李素3-O葡萄糖苷抑制MPP+诱导的PC12细胞线粒体损伤和细胞凋亡 期刊论文 李利容;傅若秋;高宁
13 用莲心碱协同长春新碱化疗的药物组合及其应用方法 专利 高宁;周静;李国兵;张宏伟
14 用莲心碱协同紫杉醇化疗的药物组合及其应用方法 专利 高宁;周静;李国兵;张宏伟
15 The cyclohexene derivative MC-3129 exhibits antileukemic activity via RhoA/ ROCK1/PTEN/PI3K/Akt pathway-mediated mitochondrial translocation of cofilin 期刊论文 Yi Zheng;Qin Ouyang;Ruoqiu Fu;Lei Liu;Hongwei Zhang;Xiaoye Hu;Yanxia Liu;Yingchun Chen;Ning Gao
16 Depletion of Ars2 inhibits cell proliferation and leukemogenesis in acute myeloid leukemia by modulating the miR-6734-3p/p27 axis. 期刊论文 Xiaoye Hu;Shuangnian Xu;Yibiao Chen;Ziyi Gao;Yunong Li;Jinjiao Hu;Xiuning Huang;Yanhao Zhang;Xiuxing Jiang;Lirong Li;Chong Yang;Jieping Chen;Ning Gao
17 ROS-mediated activation and mitochondrial translocation of CaMKII contributes to Drp1-dependent mitochondrial fission and apoptosis in triple-negative breast cancer cells by isorhamnetin and chloroquine 期刊论文 Jinjiao Hu;Yanhao Zhang;Xiuxing Jiang;Hongwei Zhang;Ziyi Gao;Yunong Li;Ruoqiu Fu;Lirong Li;Jie Li;Hongjuan Cui;Ning Gao
18 多柔比星对乳腺癌细胞核内丝切蛋白相互作用蛋白影响的比较蛋白质组学研究. 期刊论文 刘艳霞;李雨浓;傅若秋;高宁
19 BAG3的结构和功能的研究进展.. 期刊论文 刘艳霞;李雨浓;傅若秋;高宁
20 Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathway. 期刊论文 Yanhao Zhang;Ruoqiu Fu;Yanxia Liu;Jing Li;Hongwei Zhang;Xiaoye Hu;Yibiao Chen;Xin Liu;Yunong Li;Ping Li;Ehu Liu;Ning Gao
21 千金藤素增敏多柔比星抑制三阴性乳腺癌细胞增殖活性的机制研究 期刊论文 张岩昊;胡金娇;高宁
22 Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells. 期刊论文 Rong Zhang;Guobing Li;Qian Zhang;Qin Tang;Jingbin Huang;Changpeng Hu;Yali Liu;Qing Wang;Wuyi Liu;Ning Gao;Shiwen Zhou
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