基于人工杂合高亲和泛素结合蛋白的肝癌转移复发蛋白质泛素化失调分子机制的定量泛素化蛋白质组研究
31670834
2016
C2103.生命组学技术
徐平
面上项目
研究员
中国人民解放军军事科学院军事医学研究院
60万元
肝细胞癌;泛素化蛋白质组;泛素结合蛋白结构域;定量蛋白质组;转移潜能
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 泛素家族介导的蛋白质降解和细胞自噬 | 专著 | 邱小波;张宏;王琛;王琳芳;陈佺;冯仁田;胡荣贵;李汇华;谢志平;张令强;朱军;徐平 |
| 2 | Specific and Unbiased Detection of Polyubiquitination via a Sensitive Non-Antibody Approach. | 期刊论文 | Xiao Weidi;Liu Zijuan;Luo Weijia;Gao Yuan;Chang Lei;Li Yanchang;Xu Ping |
| 3 | Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation. | 期刊论文 | Li Yanchang;Dammer Eric B;Gao Yuan;Lan Qiuyan;Villamil Mark A;Duong Duc M;Zhang Chengpu;Ping Lingyan;Lauinger Linda;Flick Karin;Xu Zhongwei;Wei Wei;Xing Xiaohua;Chang Lei;Jin Jianping;Hong Xuechuan;Zhu Yunping;Wu Junzhu;Deng Zixin;He Fuchu;Kaiser Peter;Xu Ping |
| 4 | Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism | 期刊论文 | Xu Zhongwei;Zhai Linghui;Yi Tailong;Gao Huiying;Fan Fengxu;Li Yanchang;Wang Youliang;Li Ning;Xing Xiaohua;Su Na;Wu Feilin;Chang Lei;Chen Xiuli;Dai Erhei;Zhao Chao;Yang Xiao;Cui Chunping;Xu Ping |
| 5 | 人工构建的杂种泛素结合结构域多肽及其应用 | 专利 | 徐平;高媛;李衍常;赵明治;王京伟;常蕾;武军驻;贺福初 |
| 6 | 解码生命 | 专著 | 贺林;吴茜;吴胜男;谢晓亮;邢栋;徐平;许田;于军;张括 |
| 7 | 一种泛素链固相检测方法和应用 | 专利 | 李衍常;徐平;肖伟弟;高媛;常蕾;高慧英 |
| 8 | Ubiquitin Linkage Specificity of Deubiquitinases Determines Cyclophilin Nuclear Localization and Degradation | 期刊论文 | Li Yanchang;Lan Qiuyan;Gao Yuan;Xu Cong;Xu Zhongwei;Wang Yihao;Chang Lei;Wu Junzhu;Deng Zixin;He Fuchu;Finley Daniel;Xu Ping |
| 9 | Quantitative Proteomics Reveals the Development of HBV- Associated Glomerulonephritis Triggered by the Downregulation of SLC7A7 | 期刊论文 | Zuo Tao;Chen Peiru;Jing Sha;Zhang Tao;Chang Lei;Xu Feng;Zhao Chao;Xu Ping |
| 10 | Ac-LysargiNase Complements Trypsin for the Identification of Ubiquitinated Sites. | 期刊论文 | Xiao Weidi;Zhang Junling;Wang Yihao;Liu Zijuan;Wang Fuqiang;Sun Jinshuai;Chang Lei;Xia Zongping;Li Yanchang;Xu Ping |
| 11 | Recombinant expression, purification and characterization of acetylated LysargiNase from Escherichia coli with high activity and stability | 期刊论文 | Zhang Junling;Zhao Mingzhi;Xiao Weidi;Chang Lei;Wang Fuqiang;Xu Ping |
| 12 | 医学分子生物学实验技术 | 专著 | 韩骅;高国全;李冬民;喻红;徐平;赵晶;马宁 |
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