调控抗病毒天然免疫反应的长链非编码RNA的系统发现
31870893
2018
C0806.感染与非感染性炎症
周卓
面上项目
研究员
北京大学
60万元
长链非编码RNA;固有免疫;I型干扰素;高通量遗传筛选;基因编辑
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs | 期刊论文 | Xu Ping;Liu Zhiheng;Liu Ying;Ma Huazheng;Xu Yiyuan;Bao Ying;Zhu Shiyou;Cao Zhongzheng;Wu Zeguang;Zhou Zhuo;Wei Wensheng |
| 2 | Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs | 期刊论文 | Qu Liang;Yi Zongyi;Zhu Shiyou;Wang Chunhui;Cao Zhongzheng;Zhou Zhuo;Yuan Pengfei;Yu Ying;Tian Feng;Liu Zhiheng;Bao Ying;Zhao Yanxia;Wei Wensheng |
| 3 | Methods and Compositions for Editing RNAs | 专利 | 魏文胜;璩良;伊宗裔;朱诗优;王春慧;曹中正;周卓;袁鹏飞 |
| 4 | PASTMUS: mapping functional elements at single amino acid resolution in human cells | 期刊论文 | 张心怡;岳頔;王轶楠;周悦欣;刘莹;邱叶婷;田峰;于莹;周卓;魏文胜 |
| 5 | Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry | 期刊论文 | Zhu Shiyou;Liu Ying;Zhou Zhuo;Zhang Zhiying;Xiao Xia;Liu Zhiheng;Chen Ang;Dong Xiaojing;Tian Feng;Chen Shihua;Xu Yiyuan;Wang Chunhui;Li Qiheng;Niu Xuran;Pan Qian;Du Shuo;Xiao Junyu;Wang Jianwei;Wei Wensheng |
| 6 | Methods and Compositions for Editing RNAs | 专利 | 袁鹏飞;赵艳霞;刘能银;易泽轩;汤刚斌;魏文胜;璩良;伊宗裔;朱诗优;王春慧;曹中正;周卓 |
| 7 | Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection | 期刊论文 | Zhou Zhuo;Zhang Xinyi;Lei Xiaobo;Xiao Xia;Jiao Tao;Ma Ruiyi;Dong Xiaojing;Jiang Qi;Wang Wenjing;Shi Yujin;Zheng Tian;Rao Jian;Xiang Zichun;Ren Lili;Deng Tao;Jiang Zhengfan;Dou Zhixun;Wei Wensheng;Wang Jianwei |
| 8 | Circular RNA vaccines against SARS-CoV-2 and emerging variants | 期刊论文 | Liang Qu;Zongyi Yi;Yong Shen;Liangru Lin;Feng Chen;Yiyuan Xu;Zeguang Wu;Huixian Tang;Xiaoxue Zhang;Feng Tian;Chunhui Wang;Xia Xiao;Xiaojing Dong;Li Guo;Shuaiyao Lu;Chengyun Yang;Cong Tang;Yun Yang;Wenhai Yu;Junbin Wang;Yanan Zhou;Qing Huang;Ayijiang Yisimayi;Shuo Liu;Weijin Huang;Yunlong Cao;Youchun Wang;Zhuo Zhou;Xiaozhong Peng;Jianwei Wang;Xiaoliang Sunney Xie;Wensheng Wei |
| 9 | TARGETED RNA EDITING BY LEVERAGING ENDOGENOUS ADAR USING ENGINEERED RNAS | 专利 | 魏文胜;伊宗裔;璩良;田峰;王春慧;朱诗优;周卓 |
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