乙型肝炎病毒逃逸天然免疫的细胞与分子机制研究
31390431
2013
C0801.固有免疫
曹雪涛
重大项目
教授
中国医学科学院基础医学研究所
700万元
乙型肝炎病毒;免疫逃逸;干扰素刺激基因;蛋白质组学;天然免疫
2014-01至2018-12
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3 | 期刊论文 | Wang Chunmei;Wang Qinlan;Xu Xiaoqing;Xie Bin;Zhao Yong;Li Nan;Cao Xuetao |
| 2 | 天然免疫识别及其调控的分子机制研究 | 奖励 | 曹雪涛;安华章;于益芝;刘星光;徐胜;刘书逊;韩超峰;蒋应明;杨鹏远;侯晋 |
| 3 | Rb selectively inhibits innate IFN-beta production by enhancing deacetylation of IFN-beta promoter through HDACI and HDAC8 | 期刊论文 | Meng Jun;Liu Xingguang;Zhang Peng;Li Dong;Xu Sheng;Zhou Qingqing;Guo Meng;Huai Wanwan;Chen Xiang;Wang Quanxing;Li Nan;Cao Xuetao |
| 4 | Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA | 期刊论文 | Shuo Liu;Minghong Jiang;Wendie Wang;Wei Liu;Xiaoqi Song;Zhongfei Ma;Shikun Zhang;Lun Liu;Yin Liu;Xuetao Cao |
| 5 | Post-Translational Modification Control of Innate Immunity. | 期刊论文 | Liu Juan;Qian Cheng;Cao Xuetao |
| 6 | The RNA helicase DDX46 inhibits innate immunity by entrapping m(6)A-demethylated antiviral transcripts in the nucleus | 期刊论文 | Zheng Qingliang;Hou Jin;Zhou Ye;Li Zhenyang;Cao Xuetao |
| 7 | The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. | 期刊论文 | 曹雪涛| |
| 8 | 2017 most cied Chinese researchers | 奖励 | 曹雪涛 |
| 9 | Characteristics and Significance of the Pre-metastatic Niche. | 期刊论文 | Liu, Yang，Cao, Xuetao |
| 10 | 树兰奖 | 奖励 | 曹雪涛 |
| 11 | K33-linked polyubiquitination of Zap70 by Nrdp1controls CD8+ T cell activation. | 期刊论文 | Ming jin Yang; Xuetao Cao |
| 12 | An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer | 期刊论文 | Su Xiaoping;Wang Huaming;Ge Wei;Yang Mingjin;Hou Jin;Chen Taoyong;Li Nan;Cao Xuetao |
| 13 | An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism | 期刊论文 | 王品;徐俊芳;王羽佳;曹雪涛 |
| 14 | Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity | 期刊论文 | Kun Chen;Juan Liu;Shuxun Liu;Meng Xia;Xiaomin Zhang;Dan Han;Yingming Jiang;Chunmei Wang;Xuetao Cao |
| 15 | Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. | 期刊论文 | Li, Xia，Zhang, Qian，Ding, Yuanyuan，Liu, Yiqi，Zhao, Dezhi，Zhao, Kai，Shen, Qicong，Liu, Xingguang，Zhu, Xuhui，Li, Nan，Cheng, Zhongyi，Fan, Guoping，Wang, Qingqing，Cao, Xuetao |
| 16 | NIH杰出导师奖 | 奖励 | 曹雪涛 |
| 17 | Circular RNA MTO1 acts as the sponge of miR-9 to suppress hepatocellular carcinoma progression. | 期刊论文 | Han, Dan; Li, Jiangxue; Wang, Huamin; Su, Xiaoping; Hou, Jin; Gu, Yan; Qian, Cheng; Lin, Yun; Liu, Xiang; Huang, Mingyan; Li, Nan; Zhou, Weiping; Yu, Yizhi; Cao, Xuetao |
| 18 | Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation | 期刊论文 | Qicong Shen;Qian Zhang;Yang Shi;Qingzhu Shi;Yanyan Jiang;Yan Gu;Zhiqing Li;Xia Li;Kai Zhao;Chunmei Wang;Nan Li;Xuetao Cao |
| 19 | Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity. | 期刊论文 | Xia Meng;Liu Juan;Liu Shuxun;Chen Kun;Lin Hongyu;Jiang Minghong;Xu Xiaoqing;Xue Yiquan;Liu Wei;Gu Yan;Zhang Xiang;Li Zhiqing;Yi Lin;Qian Youcun;Zhou Chen;Li Ru;Zhang Xuan;Li Zhanguo;Cao Xuetao |
| 20 | 树突状细胞与免疫调控、免疫治疗的研究 | 奖励 | 曹雪涛 |
| 21 | Phosphorylation-mediated IFN-gR2 membrane translocation is required to activate macrophage innate response | 期刊论文 | Xiaoqing Xu; Jia Xu; Jiacheng Wu; Ye Hu; Yanmei Han; Yan Gu; Kai Zhao; Qian Zhang; Xingguang Liu; Juan Liu; Bing Liu; Xuetao Cao |
| 22 | 2016年度《中国科学:生命科学》优秀编委 | 奖励 | 曹雪涛 |
| 23 | Self-recognition of an inducible host lncRNA by RIG-I feedback restricts innate immune response | 期刊论文 | Minghong Jiang; Shikun Zhang; Zongheng Yang; Hongyu Lin; Jun Zhu; Lun Liu; Wendie Wang; Shuo Liu; Wei Liu; Yuanwu Ma; Lianfeng Zhang; Xuetao Cao |
| 24 | 2017年Cell 年度论文奖 | 奖励 | 曹雪涛 |
| 25 | 微小RNA的免疫调控与抗肿瘤作用及其机制研究 | 奖励 | 曹雪涛;侯晋;马烽;王品;刘星光 |
| 26 | Hepatic IFIT3 Predicts Interferon-alpha Therapeutic Response in Patients of Hepatocellular Carcinoma | 期刊论文 | Yang Yingyun;Zhou Ye;Hou Jin;Bai Chunmei;Li Zhenyang;Fan Jia;Ng Irene O. L.;Zhou Weiping;Sun Huichuan;Dong Qiongzhu;Lee Joyce M. F.;Lo Chung-Mau;Man Kwan;Yang Yun;Li Nan;Ding Guoshan;Yu Yizhi;Cao Xuetao |
| 27 | Tet2 isrequired to resolve inflammation by recruiting Hdac2 to specifically repressIL-6. | 期刊论文 | qian zhang; xuetao cao |
| 28 | The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation | 期刊论文 | Ding Yuanyuan;Guo Zhenhong;Liu Yiqi;Li Xia;Zhang Qian;Xu Xiongfei;Gu Yan;Zhang Yi;Zhao Dezhi;Cao Xuetao |
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