基于深度测序的单细胞分辨率的人胚胎干细胞亚群体和分化过程中的转录组分析

31271543
2012
C1202.干细胞应用
汤富酬
面上项目
教授
北京大学
80万元
深度测序;单细胞转录组;细胞分化;人胚胎干细胞;多能性
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Active and passive demethylation of male and female pronuclear DNA in the Mammalian zygote 期刊论文 Tang|F.|Xu|G. L.|
2 Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas 期刊论文 Hou Y|Guo H|
3 DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells 期刊论文 Guo H|Hu B|Yan L|
4 Microfluidic single-cell whole-transcriptome sequencing 期刊论文 Fu, Yusi|Zhao, Liang|Tang, Fuchou|Huang, Yanyi|
5 Epigenomic landscape of human fetal brain, heart, and liver 期刊论文 Yan L|Guo H|Hu B|
6 Single-cell RNA-seq transcriptome analysis of linear and circular RNAs in mouse preimplantation embryos. 期刊论文 Guo, Hongshan|Hu, Yuqiong|Tang, Fuchou|Huang, Yanyi|
7 Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells 期刊论文 Li|Li|J.|J.|
8 The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells. 期刊论文 Tang, Fuchou|Tang, Fuchou|Qiao, Jie|Qiao, Jie|
9 Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells 期刊论文 Kaiqin Lao|Ruiqiang Li|Jie Qiao|Fuchou Tang|
10 Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing. 期刊论文 Wu, Xinglong|Fan, Xiaoying|Wen, Lu|Tang, Fuchou|
11 The DNA methylation landscape of human early embryos 期刊论文 Tang, Fuchou|Tang, Fuchou|Qiao, Jie|Qiao, Jie|
12 Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing 期刊论文 Wu, Xinglong|Li, Xianlong|Wen, Lu|Tang, Fuchou|
13 Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells 期刊论文 Li|Li|J.|J.|
14 The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells. 期刊论文 Tang, Fuchou|Tang, Fuchou|Qiao, Jie|Qiao, Jie|
15 Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain 期刊论文 Tang, Fuchou|Tang, Fuchou|Qiao, Jie|Qiao, Jie|
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