针对SFTS的高效广谱中和纳米抗体的研发及鉴定

81803414
2018
H3404.生物技术药物
吴喜林
青年科学基金项目
研究员
南京大学
21万元
人源化小鼠;噬菌体库;腺相关病毒;纳米抗体;新型布尼亚病毒
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Infection of humanized mice with a novel phlebovirus presented pathogenic features of sever fever with thrombocytopenia syndrome 期刊论文 Xu Shijie;Jiang Na;Nawaz Waqas;Liu Bingxin;Zhang Fang;Liu Ye;Wu Xilin;Wu Zhiwei
2 Potent Neutralizing Humanized Antibody With Topical Therapeutic Potential Against HPV18-Related Cervical Cancer 期刊论文 Huang Bilian;Zhu Linjing;Wei Hongxia;Shi Haixia;Zhang Doudou;Yuan Huanyun;Luan Linlin;Zheng Nan;Xu Shijie;Nawaz Waqas;Hong Ying;Wu Xilin;Wu Zhiwei
3 Antibody recognizing designed epitope of three or more amino acid residues in a peptide and method of generating thereof 专利 吴稚伟;吴喜林
4 AAV-mediated in vivo CAR gene therapy for targeting human T-cell leukemia 期刊论文 Nawaz Waqas;Huang Bilian;Xu Shijie;Li Yanlei;Zhu Linjing;Yiqiao Hu;Wu Zhiwei;Wu Xilin
5 A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration 期刊论文 Wu Xilin;Cheng Lin;Fu Ming;Huang Bilian;Zhu Linjing;Xu Shijie;Shi Haixia;Zhang Doudou;Yuan Huanyun;Nawaz Waqas;Yang Ping;Hu Qinxue;Liu Yalan;Wu Zhiwei
6 一种用于诊断SFTS患者预后情况的蛋白质及其应用 专利 吴稚伟;吴喜林;马晓花
7 可结合SFTSV的多肽、其核酸编码序列及应用 专利 吴喜林;吴稚伟;李彦磊;潘逸
8 抗CD19抗体及其应用 专利 吴喜林;吴稚伟;王宏伟
9 Dna motif compounds and methods for inducing specific antibodies and cellular immunity 专利 Chen Zhiwei;Wu Xilin;Wu Zhiwei
10 Efficacy of potent neutralizing nanobody against SFTSV in humanized mice 会议论文 Wu Xilin;Li Yanlei;Pan Yi;Zhu Linjing;Yuan Huanyun;Wu Zhiwei
11 A single-domain antibody inhibits SFTSV and mitigates virus-induced pathogenesis in vivo 期刊论文 Xilin Wu;Yanlei Li;Bilian Huang;Xiaohua Ma;Linjing Zhu;Nan Zheng;Shijie Xu;Waqas Nawaz;Changping Xu;Zhiwei Wu
12 任意三个或以上氨基酸残基构成的多肽表位及其相关抗体的诱导 专利 吴稚伟;吴喜林
13 Nanotechnology and immunoengineering: How nanotechnology can boost CAR-T therapy 期刊论文 Nawaz Waqas;Xu Shijie;Li Yanlei;Huang Bilian;Wu Xilin;Wu Zhiwei
14 The induction and characterization of monoclonal antibodies specific to GP of Ebola virus 期刊论文 Xiaoyan Tian;Deyan Chen;Huanru Wang;Shijie Xu;Linjing Zhu;Xilin Wu;Zhiwei Wu
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