基于网络控制的复杂疾病药物标靶识别研究

61428209
2014
F0213.生物信息计算与数字健康
吴方向
海外及港澳学者合作研究基金
教授
中南大学
20万元
复杂疾病；药物标靶；控制理论；致病基因；分子网络
2015-01至2016-12
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Network Output Controllability-Based Method for Drug Target Identification 期刊论文 Lin Wu;Yichao Shen;Min Li;Fang-Xiang Wu
2 A two-step logistic regression algorithm for identifying individual-cancer-related genes 会议论文 Chen Bolin;Shang Xuequn;Li Min;Wang Jianxin;Wu Fang Xiang
3 LDAP: a web server for lncRNA-disease association prediction. 期刊论文 Jin Liu|Fangxiang Wu|Yi Pan|Jianxin Wang|
4 ProSim: A Method for Prioritizing Disease Genes Basedon Protein Proximity and Disease Similarity 期刊论文 Gamage Upeksha Ganegoda|Yu Sheng|Jianxin Wang|
5 Applications of Random Walk Model on Biological Networks 期刊论文 Wei Peng|Jianxin Wang|Zhen Zhang|Fangxiang Wu|
6 Predicting essential proteins based on subcellular localization, orthology and PPI networks 期刊论文 Gaoshi Li();Min Li();Jianxin Wang();Jingli Wu;Fang-Xiang Wu;Yi Pan
7 Identifying Essential Proteins by Purifying Protein Interaction Networks 会议论文 Min Li()();Xiaopei Chen;Peng Ni;Jianxin Wang;Yi Pan
8 Predicting drug-target interaction based on sequence and structure information 会议论文 Wei Lan;Jianxin Wang();Min Li;Ruiqing Zheng;Fang-Xiang Wu;Yi Pan
9 Disease gene identification by using graph kernels and Markov random fields 期刊论文 BoLin Chen;Min Li;JianXin Wang;FangXiang Wu
10 A Topology Potential-Based Method for Identifying Essential Proteins from PPI Networks. 期刊论文 Yu Lu|Jianxin Wang|Fangxiang Wu|Yi Pan|
11 Predicting protein functions by using unbalanced random walk algorithmon three biological networks 期刊论文 Wei Peng|Min Li|Lu Chen|Lusheng Wang|
12 Minimum steering node set of complex networks and its applications to biomolecular networks 期刊论文 Lin Wu|Min Li|Jianxin Wang|Fangxiang Wu|
13 Heterogeneous Network Model to Infer Human Disease-Long Intergenic Non-Coding RNA Associations 期刊论文 Ganegoda Gamage Upeksha;Li Min;Wang Weiping;Feng Qilong
14 A New Method for Predicting Protein Functions From Dynamic Weighted Interactome Networks 期刊论文 Bihai Zhao;Jianxin Wang();Min Li;Xueyong Li;Yaohang Li;Fang-Xiang Wu;Yi Pan
15 Essential protein discovery based on a combination of modularity and conservatism 期刊论文 Bihai Zhao;Jianxin Wang();Xueyong Li;Fang-Xiang Wu
16 United complex centrality for identification of essential proteins from PPI networks 期刊论文 Min Li（第一作者）;Yu Lu;Zhibei Niu;Fangxiang Wu
17 Drug repositioning based on comprehensive similarity measures and Bi-Random walk algorithm 期刊论文 Huimin Luo;Jianxin Wang();Min Li;Junwei Luo;Xiaoqing Peng;Fang-Xiang Wu;Yi Pan
18 VAliBS: A Visual Aligner for Bisulfite Sequences 会议论文 Li Min;Yan Xiaodong;Zhao Lingchen;Wang Jianxin;Wu Fang-Xiang;Pan Yi
19 Prioritizing Disease Genes by Using Search Engine Algorithm 期刊论文 Li Min();Zheng Ruiqing;Li Qi;Wang Jianxin();Wu Fang-Xiang;Zhang Zhuohua
20 Identification of protein complexes from multi-relationship protein interaction networks 期刊论文 Li Xueyong();Wang Jianxin();Zhao Bihai;Wu Fang-Xiang;Pan Yi
21 Prioritization of orphan disease-causing genes using topological feature and GO similarity between proteins in interaction networks 期刊论文 Li Min();Li Qi;Ganegoda Gamage Upeksha;Wang JianXin();Wu FangXiang;Pan Yi
22 A logistic regression based algorithm for identifying human disease genes 会议论文 Chen Bolin;Li Min;Wang Jianxin;Wu Fang-Xiang
23 Identifying Individual-Cancer-Related Genes by Rebalancing the Training Samples 期刊论文 Bolin Chen;Xuequn Shang;Min Li;Jianxin Wang;Fang-Xiang Wu
24 Predicting microRNA-disease associations by integrating multiple biological information 会议论文 Wei Lan;Jianxin Wang;Min Li;Jin Liu;Fang-xiang Wu;Yi Pan
25 A reliable neighbor-based method for identifying essential proteins by integrating gene expressions, orthology, and subcellular localization information 期刊论文 Min Li;Zhibei Niu;Xiaopei Chen;Ping Zhong;Fangxiang Wu;Yi Pan
26 Predicting protein functions based on dynamic protein interaction networks 会议论文 Bihai Zhao|Jianxin Wang|Fangxiang Wu|Yi Pan|
27 The MSS of Complex Networks with Centrality Based Preference and Its Application to Biomolecular Networks 会议论文 Lingkai Tang|Min Li|Jianxin Wang|Fangxiang Wu|
28 Predicting microRNA-disease associations based on improved microRNA and disease similarities 期刊论文 Wei Lan;Jianxin Wang();Min Li;Jin Liu;Fang-Xiang Wu;Yi Pan
29 Construction of the spatial and temporal active protein interaction network for identifying protein complexes 会议论文 Xiangmao Meng;Min Li;Jianxin Wang;Fang-Xiang Wu;Yi Pan
30 Predicting drug–target interaction using positive-unlabeled learning 期刊论文 Min Li|Yaohang Li|Fangxiang Wu|Yi Pan|
31 Identifying essential proteins from active PPI networks constructed with dynamic gene expression. 期刊论文 Jianxin Wang|Xiaoqing Peng|Fangxiang Wu|Yi Pan|
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