面向难愈合骨缺损高效修复的新型微纳米生物活性材料基础与应用研究

U1501245
2015
C1001.生物力学与生物流变学
陈晓峰
联合基金项目
教授
华南理工大学
244万元
基因介导;3D构建;骨修复;生物因子装载;微纳米生物活性玻璃
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A highly bioactive bone extracellular matrix-biomimetic nanofibrous system with rapid angiogenesis promotes diabetic wound healing 期刊论文 Gao Wendong;Jin Wanwan;Li Yannan;Wan Li;Wang Chenggui;Lin Cai;Chen Xiaofeng;Lei Bo;Mao Cong
2 生物活性玻璃纤维-聚己内酯复合膜及其制备方法与应用 专利 陈晓峰;刘惠;李贤;林泽峰;李玉莉
3 Enhanced diabetic wound healing by electrospun core-sheath fibers loaded with dimethyloxalylglycine 期刊论文 Gao W;Sun L;Fu X;Lin Z;Xie W;Zhang W;Zhao F;Chen X
4 The Preparation of Hollow Mesoporous Bioglass Nanoparticles With Excellent Drug Delivery Capacity for Bone Tissue Regeneration 期刊论文 Wang Yudong;Pan Haobo;Chen Xiaofeng
5 生物材料与组织再生 专著 陈晓峰
6 Highly efficient local delivery of endothelial progenitor cells significantly potentiates angiogenesis and full-thickness wound healing 期刊论文 Wang Chenggui;Wang Qingqing;Gao Wendong;Zhang Zengjie;Lou Yiting;Jin Haiming;Chen Xiaofeng;Lei Bo;Xu Huazi;Mao Cong
7 Dose-dependent modulation effects of bioactive glass particles on macrophages and diabetic wound healing 期刊论文 Xie Weihan;Fu Xiaoling;Tang Fengling;Mo Yunfei;Cheng Jun;Wang Hongjun;Chen Xiaofeng
8 一种结构尺寸可调节的水凝胶及其制备方法和应用 专利 曾蕾;陈晓峰;曹晓东;王刚
9 生物医学材料学-制备与性能 专著 陈晓峰
10 一种利用微乳液技术制备的微纳米生物活性玻璃微球及其制备方法 专利 陈晓峰;王聿栋;孙璐瑶;莫云飞;陈雪颖;罗曼
11 Characterization of the mechanical behaviors and bioactivity of tetrapod ZnO whiskers reinforced bioactive glass/gelatin composite scaffolds 期刊论文 Guo Weihuang;Zhao Fujian;Wang Yudong;Tang Jieyin;Chen Xiaofeng
12 一种微纳米棒状生物活性玻璃及其制备方法与应用 专利 陈晓峰;胡庆;李玉莉;苗国厚
13 A Hyaluronic Acid Based Injectable Hydrogel Formed via Photo-Crosslinking Reaction and Thermal-Induced Diels-Alder Reaction for Cartilage Tissue Engineering 期刊论文 Wang Gang;Cao Xiaodong;Dong Hua;Zeng Lei;Yu Chenxi;Chen Xiaofeng
14 Sequentially-crosslinked biomimetic bioactive glass/gelatin methacryloyl composites hydrogels for bone regeneration 期刊论文 Zheng Jiafu;Zhao Fujian;Zhang Wen;Mo Yunfei;Zeng Lei;Li Xian;Chen Xiaofeng
15 Size-Dependent Mechanism of Intracellular Localization and Cytotoxicity of Mono-Disperse Spherical Mesoporous Nano- and Micron-Bioactive Glass Particles 期刊论文 Yuli Li;QingHu;Guohou Miao;Qing Zhang;BoYuan;Ye Zhu;Xiaoling Fu;Xiaofeng Chen;Chuanbin Mao
16 Bio-inspired bioactive glasses for efficient microRNA and drug delivery 期刊论文 Li Xian;Liang Qiming;Zhang Wen;Li Yuli;Ye Jiandong;Zhao Fujian;Chen Xiaofeng;Wang Shiren
17 Cationic Polyarginine Conjugated Mesoporous Bioactive Glass Nanoparticles with Polyglycerol Coating for Efficient DNA Delivery 期刊论文 Li Xian;Zhao Li;Liang Qiming;Ye Jiandong;Komatsu Naoki;Zhang Qing;Gao Wendong;Xu Meiyun;Chen Xiaofeng
18 一种用于治疗牙本质过敏症的脱敏剂及其制备方法 专利 陈晓峰;唐洁吟;赵夫健;王聿栋;刘聪
19 一种含多级孔结构的生物活性玻璃/聚乳酸-羟基乙酸共聚物(PLGA)复合支架及其制备方法 专利 陈晓峰;田婷;陈雪颖;史淼;曾蕾
20 Fabrication of bioactive glass particles composite porous fibers by combination of electrospinning and phase separation 期刊论文 Xie Weihan;Fu Xiaoling;Wang Yu Dong;Wang Gang;Chen Xiaofeng
21 一种支架下种植系统及其植入方法 专利 陈晓峰;赵夫健;唐洁吟;郭炜煌;郑佳富;史淼
22 一种生物玻璃-海藻酸钠复合生物材料及试剂盒和应用 专利 陈晓峰;梁绮明;胡庆;李玉莉;李贤
23 Facile synthesis of mesoporous bioactive glass nanospheres with large mesopore via biphase delamination method 期刊论文 Tang Jieyin;Chen Xiaofeng;Dong Yanmei;Fu Xiaoling;Hu Qing
24 一种具有表面纳米孔隙结构的微纳米生物活性玻璃微球及其制备方法 专利 陈晓峰;王聿栋;孙璐瑶;赵夫健;田婷
25 The effects of Sr concentration on physicochemical properties, bioactivity and biocompatibility of sub-micron bioactive glasses spheres 期刊论文 Hu Qing;Jiang Weihui;Chen Xiaofeng;Li Yuli;Liang Qiming
26 一种生物活性玻璃复合多层纳米纤维支架及其制备方法 专利 曾蕾;高文东;陈晓峰;王刚
27 Micro-Nano Bioactive Glass Particles Incorporated Porous Scaffold for Promoting Osteogenesis and Angiogenesis in vitro 期刊论文 Tian Ting;Xie Weihan;Gao Wendong;Wang Gang;Zeng Lei;Miao Guohou;Lei Bo;Lin Zhanyi;Chen Xiaofeng
28 一种结构仿生皮肤细胞外基质的复合纳米纤维膜及其制备方法与应用 专利 陈晓峰;孙璐瑶;付晓玲;高文东
29 Facile synthesis and characterization of novel rapid-setting spherical sub-micron bioactive glasses cements and their biocompatibility in vitro 期刊论文 Li Yuli;Liang Qiming;Lin Cai;Li Xian;Chen Xiaofeng;Hu Qing
30 Facile synthesis of hollow mesoporous bioactive glasses with tunable shell thickness and good monodispersity by micro-emulsion method 期刊论文 yudong wang;xiaofeng chen
31 自交联生物活性玻璃/海藻酸钠支架的制备方法及应用 专利 陈晓峰;赵夫健;张文;王聿栋;唐洁吟;郭炜煌
32 一种生物活性玻璃复合支架及其制备方法 专利 陈晓峰;郭炜煌;赵夫健;王聿栋;唐洁吟
33 一种掺铒荧光生物活性玻璃及其制备方法 专利 陈晓峰;杨峥宇;陈建辉
34 Synergistic effect of strontium and silicon in strontium-substituted sub-micron bioactive glass for enhanced osteogenesis 期刊论文 Zhang Wen;Huang Deqiu;Zhao Fujian;Gao Wendong;Sun Luyao;Li Xian;Chen Xiaofeng
35 一种基于生物活性玻璃-壳聚糖的复合活髓保存材料及其制备方法 专利 陈晓峰;曾诗涵;刘聪;唐凤玲;欧阳鹿;田婷;王刚;曾蕾
36 一种3D打印针头和料筒装置 专利 陈晓峰;赵夫健;张文;王聿栋;葛倩倩
37 The effects of morphology on physicochemical properties, bioactivity and biocompatibility of micro-/nano-bioactive glasses 期刊论文 Hu Qing;Jiang Weihui;Li Yuli;Chen Xiaofeng;Liu Jianmin;Chen Ting;Miao Guohou
38 一种高钙磷含量的微纳米生物活性玻璃微球及其制备方法 专利 陈晓峰;陈雪颖;田婷;莫云飞
39 Preparation and characterization of folic acid functionalized bioactive glass for targeted delivery and sustained release of methotrexate 期刊论文 Chen Jianhui;Chen Xiaofeng;Yang Zhengyu;Tan Xiaojun;Wang Jiachen;Chen Yao
40 一种多孔纤维/无机生物材料颗粒复合型皮肤创面敷料及其制备方法 专利 陈晓峰;谢委翰;付晓玲;曾蕾
41 一种生物活性玻璃复合纳米纤维膜及其制备方法 专利 陈晓峰;高文东;付晓玲;孙璐瑶
42 医用生物玻璃 专著 陈晓峰
43 Facile synthesis and in vitro bioactivity of radial mesoporous bioactive glasses 期刊论文 Wang Yudong;Liao Tianshun;Shi Miao;Liu Cong;Chen Xiaofeng
44 一种叶酸靶向抗肿瘤药物缓释载体及其制备方法 专利 陈晓峰;陈建辉;杨峥宇;谭晓君;王佳晨;陈瑶
45 一种生物活性玻璃-改性明胶复合水凝胶及其制备方法 专利 陈晓峰;郑佳富
46 Bioimplants, Regenerative Medicine, and Nano-Cancer Diagnosis and Phototherapy Volume 3: Design of Bioactive Materials for Bone Repair and Regeneration, Chapter 4: Bioactive Glasses 专著 陈晓峰;胡庆
47 Strontium-Substituted Submicrometer Bioactive Glasses Modulate Macrophage Responses for Improved Bone Regeneration 期刊论文 Wen Zhang;Fujian Zhao;Deqiu Huang;Xiaoling Fu;Xian Li;Xiaofeng Chen
48 Alginate based antimicrobial hydrogels formed by integrating Diels-Alder "click chemistry" and the thiol-ene reaction 期刊论文 Wang Gang;Zhu Jiehua;Chen Xiaofeng;Dong Hua;Li Qingtao;Zeng Lei;Cao Xiaodong
49 Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes 期刊论文 Zhao Fujian;Lei Bo;Li Xian;Mo Yunfei;Wang Renxian;Chen Dafu;Chen Xiaofeng
50 Fabrication and characterization of bioactive glass alginate composite scaffolds by a self-crosslinking processing for bone regeneration 期刊论文 Fujian Zhao;Wen Zhang;Xiaoling Fu;Weihan Xie;Xiaofeng Chen
51 3D Printing Nanoscale Bioactive Glass Scaffolds Enhance Osteoblast Migration and Extramembranous Osteogenesis through Stimulating Immunomodulation 期刊论文 Zhao Fujian;Xie Weihan;Zhang Wen;Fu Xiaoling;Gao Wendong;Lei Bo;Chen Xiaofeng
52 掺锶生物活性玻璃通过调控巨噬细胞极化促进成骨 期刊论文 张文;黄德球;郭周义;陈晓峰
53 Preparation and characterization of bioactive glass tablets and evaluation of bioactivity and cytotoxicity in vitro 期刊论文 Chen J;Zeng L;Chen X;Liao T;Zheng J
54 一种生物活性玻璃多孔骨修复体材料及其制备方法 专利 陈晓峰;廖天舜;陈建辉;欧阳鹿;罗曼
55 Preparation and properties of poly(epsilon-caprolactone)/bioactive glass nanofibre membranes for skin tissue engineering 期刊论文 Lin Zefeng;Gao Wendong;Ma Limin;Xia Hong;Xie Weihan;Zhang Yu;Chen Xiaofeng
56 一种改性生物活性玻璃/聚丙烯酰胺/氧化海藻酸钠水凝胶敷料及其制备方法 专利 陈晓峰;董亮亮
57 Enhanced wound healing in diabetic rats by nanofibrous scaffolds mimicking the basketweave pattern of collagen fibrils in native skin 期刊论文 Sun Luyao;Gao Wendong;Fu Xiaoling;Shi Miao;Xie Weihan;Zhang Wen;Zhao Fujian;Chen Xiaofeng
58 Alginate based antimicrobial hydrogels formed by integrating Diels-Alder "click chemistry" and the thiol-ene reaction 期刊论文 Wang Gang;Zhu Jiehua;Chen Xiaofeng;Dong Hua;Li Qingtao;Zeng Lei;Cao Xiaodong
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