Btk促进β2整合素激活介导嗜中性粒细胞募集和迁移的力调控机制研究

31870928
2018
C1001.生物力学与生物流变学
李趣欢
面上项目
副教授
华南理工大学
59万元
Btk激酶;选择素;力学-化学耦合;受体-配体相互作用;整合素
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 采用分子动力学模拟技术探究BTK及其抑制剂之间的相互作用 期刊论文 于翔凡;邱思枚;方颖;吴建华;李趣欢
2 Stage‐specific regulation of Gremlin1 on the differentiation and expansion of human urinary induced pluripotent stem cells into endothelial progenitors 期刊论文 Haixuan Chen;Zhen Zhang;Zhecun Wang;Quhuan Li;Hui Chen;Song Guo;Lin Bao;Zheng Wang;Wang Min;Qiuling Xiang
3 A mechanism for localized dynamics-driven activation in Bruton's tyrosine kinase 期刊论文 Qiu Simei;Liu Yunfeng;Li Quhuan
4 整合素α_vβ_6与纤连蛋白相互作用的力调控机制 期刊论文 杨碧珊;李娜;李趣欢
5 Upregulation of the Long Non-coding RNA LINC01480 Is Associated With Immune Infiltration in Coronary Artery Disease Based on an Immune-Related lncRNA-mRNA Co-expression Network 期刊论文 Ting Xiong;Botao Xiao;Yueheng Wu;Yunfeng Liu;Quhuan Li
6 Downregulation of long noncoding RNA LINC00683 associated with unfavorable prognosis in prostate cancer based on TCGA 期刊论文 Liu Yunfeng;Yang Bishan;Su Youmin;Xiang Qiuling;Li Quhuan
7 Comparison of Linear vs. Cyclic RGD Pentapeptide Interactions with Integrin alpha(v)beta(3) by Molecular Dynamics Simulations 期刊论文 Li Na;Qiu Simei;Fang Ying;Wu Jianhua;Li Quhuan
8 Construction of a Comprehensive Diagnostic Scoring Model for Prostate Cancer Based on a Novel Six-Gene Panel 期刊论文 Yunfeng Liu;Simei Qiu;Dongshan Sun;Ting Xiong;Qiuling Xiang;Quhuan Li
9 Biphasic Force-Regulated Phosphorylation Site Exposure and Unligation of ERM Bound with PSGL-1: A Novel Insight into PSGL-1 Signaling via Steered Molecular Dynamics Simulations 期刊论文 Feng Jingjing;Zhang Yan;Li Quhuan;Fang Ying;Wu Jianhua
10 一种流体剪切力诱导肿瘤细胞跨膜迁移的微流控芯片装置 专利 李趣欢;刘云峰;吴建华;方颖
11 EVI1高表达AML的潜在治疗新靶点GNGT2 期刊论文 刘云峰;王林;杨碧珊;粟尤敏;李趣欢
12 流体环境下BTK对肿瘤细胞的黏附和增殖影响的研究 期刊论文 邱思枚;于翔凡;方颖;吴建华;李趣欢
13 冠心病中免疫lncRNA-mRNA加权共表达网络的构建和关键lncRNA的筛选 期刊论文 熊厅;肖波涛;方颖;吴建华;李趣欢
14 PPBP as a marker of diabetic nephropathy podocyte injury via Bioinformatics Analysis 期刊论文 Zhang Fengxia;Jiang Nan;Gao Yan;Fan Zuyan;Li Quhuan;Ke Guibao;Li Bohou;Wu Qiong;Xu Ruiquan;Liu Shuangxin
15 Comparison of Intermolecular Interactions of Irreversible and Reversible Inhibitors with Bruton’s Tyrosine Kinase via Molecular Dynamics Simulations 期刊论文 Xiangfan Yu;Simei Qiu;Dongshan Sun;Pei Guo;Quhuan Li
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