狼疮病程中TLR7信号通过Dectin-3/CARD9轴调控MDSCs数量及功能的机制

31872732
2018
C0801.固有免疫
侯亚义
面上项目
教授
南京大学
58万元
微环境;树突状细胞相关性C型植物血凝素-3;系统性红斑狼疮;髓系抑制性细胞;Toll;样受体7
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB 期刊论文 Zhiheng Sun;Yuchen Pan;Junxing Qu;Yujun Xu;Huan Dou;Yayi Hou
2 MDSCs: friend or foe in systemic lupus erythematosus 期刊论文 Jianjian Ji;Pengfei Li;Cunsi Shen;Huan Dou;Tingting Wang;Liyun Shi;Yayi Hou
3 Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells 期刊论文 Dan Li;Guoping Shi;Jiali Wang;Dongya Zhang;Yuchen Pan;Huan Dou;Yayi Hou
4 Bacteroides fragilis alleviates the symptoms of lupus nephritis via regulating CD1d and CD86 expressions in B cells 期刊论文 Li Dan;Pan Yuchen;Xia Xiaoyu;Liang Jun;Liu Fei;Dou Huan;Hou Yayi
5 IRF-8/miR-451a regulates M-MDSC differentiation via the AMPK/mTOR signal pathway during lupus development 期刊论文 Shi Guoping;Li Dan;Zhang Dongya;Xu Yujun;Pan Yuchen;Lu Li;Li Jingman;Xia Xiaoyu;Dou Huan;Hou Yayi
6 Hippocampal microglia CD40 mediates NPSLE cognitive dysfunction in mice 期刊论文 Xiaoyue Qiao;Hailin Wang;Li Lu;Jinglei Chen;Qinpei Cheng;Meng Guo;Yayi Hou;Huan Dou
7 Urokinase-type plasminogen activator receptor is required for impairing toll-like receptor 7 signaling on macrophage efferocytosis in lupus 期刊论文 Jingman Li;Yuchen Pan;Dan Li;Xiaoyu Xia;Qi Jiang;Huan Dou;Yayi Hou
8 C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1+ M-MDSCs in relieving lupus-like symptoms 期刊论文 Dan Li;Li Lu;Wei Kong;Xiaoyu Xia;Yuchen Pan;Jingman Li;Jiali Wang;Tingting Wang;Jun Liang;Huan Dou;Yayi Hou
9 mTOR inhibitor INK128 attenuates systemic lupus erythematosus by regulating inflammation-induced CD11b+Gr1+ cells 期刊论文 Guoping Shi;Dan Li;Xiaojing Li;Jing Ren;Jingjing Xu;Liang Ding;Huan Dou;Yayi Hou
10 17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis 期刊论文 Zhiheng Sun;Junxing Qu;Xiaoyu Xia;Yuchen Pan;Xinghan Liu;Huaping Liang;Huan Dou;Yayi Hou
11 A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury 期刊论文 Wei Gong;Haiyan Zhu;Li Lu;Yayi Hou;Huan Dou
12 Protective effect of dihydroartemisinin in inhibiting senescence of myeloid-derived suppressor cells from lupus mice via Nrf2/HO-1 pathway 期刊论文 Li Dan;Qi Jingjing;Wang Jiali;Pan Yuchen;Li Jingman;Xia Xiaoyu;Dou Huan;Hou Yayi
13 Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathway 期刊论文 Li Lu;Hailin Wang;Xuan Liu;Liping Tan;Xiaoyue Qiao;Jiali Ni;Yang Sun;Jun Liang;Yayi Hou;Huan Dou
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