肿瘤微环境敏感的高效siRNA纳米传输体系的构建及应用研究

21805314
2018
B0507.医用材料化学
王勇
青年科学基金项目
副教授
暨南大学
28万元
肿瘤微环境;靶向药物传递;药物控制释放;抗癌纳米药物;小干扰RNA输送
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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1 A pH and reduction dual-sensitive polymeric nanomicelle for tumor microenvironment triggered cellular uptake and controlled intracellular drug release 期刊论文 Zhenwei Su;Yongmin Xu;Yong Wang;Wanqi Shi;Shisong Han;Xintao Shuai
2 Nanodrug with ROS and pH Dual-Sensitivity Ameliorates Liver Fibrosis via Multicellular Regulation 期刊论文 Liteng Lin;Hengye Gong;Rui Li;Jingjun Huang;Mingyue Cai;Tian Lan;Wensou Huang;Yongjian Guo;Zhimei Zhou;Yongcheng An;Zhiwei Chen;Licong Liang;Yong Wang;Xintao Shuai;Kangshun Zhu
3 Cleavable bimetallic-organic polymers for ROS mediated cascaded cancer therapy under the guidance of MRI through tumor hypoxia relief strategy 期刊论文 Haozhe He;Lihua Du;Min Tan;Yali Chen;Liejing Lu;Yongcheng An;Yong Wang;Xiaoxia Li;Bo Li;Jun Shen;Jun Wu;Xintao Shuai
4 Polymeric Vector-Mediated Targeted Delivery of Anti-PAK1 siRNA to Macrophages for Efficient Atherosclerosis Treatment 期刊论文 Teng Wu;Hong Xiao;Liejing Lu;Yali Chen;Yong Wang;Wenhao Xia;Ming Long;Jun Tao;Jun Shen;Xintao Shuai
5 A polymer‑calcium phosphate nanocapsule for RNAi-induced oxidative stress and cascaded chemotherapy 期刊论文 Jinsheng Huang;Chujie Zheng;Hong Xiao;Huiling Huang;Yiyao Wang;Minzhao Lin;Jun Pang;Yong Wang;Yuanyuan Yuan;Xintao Shuai
6 The programmed site-specific delivery of the angiostatin sunitinib and chemotherapeutic paclitaxel for highly efficient tumor treatment 期刊论文 Jin He;Hong Xiao;Bo Li;Yuan Peng;Xiaoxia li;Yong Wang;Grazyna Adamus;Marek Kowalczuk;Xintao Shuai
7 I6P7 peptide modified superparamagnetic iron oxide nanoparticles for magnetic resonance imaging detection of low-grade brain gliomas 期刊论文 Junyi Tan;Weitong Sun;Liejing Lu;Zecong Xiao;Huiye Wei;Wanqi Shi;Yong Wang;Shisong Han;Xintao Shuai
8 Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy 期刊论文 Jinsheng Huang;Zecong Xiao;Yongcheng An;Shisong Han;Wei Wu;Yong Wang;Yu Guo;Xintao Shuai
9 Redox Responsive Metal Organic Framework Nanoparticles Induces Ferroptosis for Cancer Therapy 期刊论文 Haozhe He;Lihua Du;Huanling Guo;Yongcheng An;Liejing Lu;Yali Chen;Yong Wang;Huihai Zhong;Jun Shen;Jun Wu;Xintao Shuai
10 一种三嵌段聚合物、载药纳米胶束、纳米药物及其制备方法和应用 专利 帅心涛;何进;肖洪;王勇
11 Codelivery of Anti-PD-1 Antibody and Paclitaxel with Matrix Metalloproteinase and pH Dual-Sensitive Micelles for Enhanced Tumor Chemoimmunotherapy 期刊论文 Zhenwei Su;Zecong Xiao;Yong Wang;Jinsheng Huang;Yongcheng An;Xu Wang;Xintao Shuai
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