基于ALDOA介导自噬调控的LYG-202治疗肠炎的作用及机制研究

81903626
2019
H3504.抗炎与免疫药物药理
赵越
青年科学基金项目
副教授
中国药科大学
20万元
糖酵解;自噬;黄酮化合物;炎症性肠病;果糖二磷酸醛缩酶
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation 期刊论文 Bai Dongsheng;Du Jiaying;Bu Xiumin;Cao Wangjia;Sun Tifan;Zhao Jiawei;Zhao Yue;Lu Na
2 Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. 期刊论文 Yang Dawei;Guo Qinglong;Liang Yin;Zhao Yue;Tian Xiaoyu;Ye Yuchen;Tian Jieyi;Wu Tao;Lu Na
3 Oroxylin A maintains the colonic mucus barrier to reduce disease susceptibility by reconstituting a dietary fiber-deprived gut microbiota 期刊论文 Bai Dongsheng;Sun Tifan;Zhao Jiawei;Du Jiaying;Bu Xiumin;Cao Wangjia;Zhao Yue;Lu Na
4 Induction of cell cycle arrest and apoptosis by CPUC002 through stabilization of p53 and suppression of STAT3 signaling pathway in multiple myeloma. 期刊论文 Zhao Yue;Bai Dongsheng;Du Jiaying;Ren Haochuan;Zhang Zhenguo;Jiang Cheng;Lu Na
5 Triggering apoptosis by oroxylin A through caspase-8 activation and p62/SQSTM1 proteolysis 期刊论文 Zhao Yue;Zhu Qin;Bu Xiumin;Zhou Yihui;Bai Dongsheng;Guo Qinglong;Gao Yuan;Lu Na
6 A novel kinase inhibitor, LZT-106, downregulates Mcl-1 and sensitizes colorectal cancer cells to BH3 mimetic ABT-199 by targeting CDK9 and GSK-3 beta signaling 期刊论文 Yu Zhou;Du Jiaying;Zhao Yue;Gao Yuan;Li Yongxu;Zhao Kai;Lu Na
7 The flavonoid GL‐V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells 期刊论文 Zhao Jiawei;Bai Dongsheng;Qi Lei;Cao Wangjia;Du Jiaying;Gu Chunyang;Zhou Chen;Gao Yuan;Zhang Lulu;Zhao Yue;Lu Na
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