基于新激活剂壳寡糖的TMEM16A离子通道门控机制研究
31400711
2014
C0503.细胞感应与环境生物物理
陈娅斐
青年科学基金项目
副教授
河北工业大学
24万元
壳寡糖;TMEM16A离子通道;平滑肌收缩反应;门控机制;激活剂
2015-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 含牛磺酸的药物组合物及其应用 | 专利 | 陈娅斐;郭帅;展永;安海龙;耿金鹏;柳辉;王徐朝;莫莉 |
| 2 | 含苦参碱的药物组合物及其应用 | 专利 | 安海龙;郭帅;展永;陈娅斐;张素花;耿金鹏;王徐朝;莫莉 |
| 3 | Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A | 期刊论文 | Chai Ran;Chen Yafei;Yuan Hongbo;Wang Xuzhao;Guo Shuai;Qi Jinlong;Zhang Hailin;Zhan Yong;An Hailong |
| 4 | Anti-tumor effects of (1 -> 3)-beta-D-glucan from Saccharomyces cerevisiae in S180 tumor-bearing mice | 期刊论文 | Mo Li;Chen Yafei;Li Wenjian;Guo Shuai;Wang Xuzhao;An Hailong;Zhan Yong |
| 5 | Two Ca2+-Binding Sites Cooperatively Couple Together in TMEM16A Channel | 期刊论文 | Han Yuebin;Zhang Suhua;Ren Shuxi;Chen Yafei;Yuan Hongbo;Chai Ran;Yu Hui;Zhang Hailin;Zhan Yong;An Hailong |
| 6 | Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions | 期刊论文 | Guan Ronghua;Zhou Hui;Li Junwei;Xiao Shaoying;Pang Chunli;Chen Yafei;Du Xiangrong;Ke Shaoxi;Tang Qiongyao;Su Jiguo;Zhan Yong;An Hailong |
| 7 | 一种TMEM16A钙激活氯离子通道抑制剂的筛选方法 | 专利 | 展永;陈娅斐;郭鹏;安海龙;耿金鹏;王晖;袁宏博;赵小明;杜昱光 |
| 8 | Eag1 Voltage-Dependent Potassium Channels: Structure, Electrophysiological Characteristics, and Function in Cancer | 期刊论文 | Wang Xuzhao;Chen Yafei;Zhang Yuhong;Guo Shuai;Mo Li;An Hailong;Zhan Yong |
| 9 | Ginsenoside Rb1, a novel activator of the TMEM16A chloride channel, augments the contraction of guinea pig ileum | 期刊论文 | Guo Shuai;Chen Yafei;Pang Chunli;Wang Xuzhao;Qi Jinlong;Mo Li;Zhang Hailin;An Hailong;Zhan Yong |
| 10 | 一种TMEM16A钙激活氯离子通道激活剂的筛选方法 | 专利 | 展永;陈娅斐;郭鹏;安海龙;耿金鹏;王晖;袁宏博;赵小明;杜昱光 |
| 11 | Allosteric Mechanism of Calmodulin Revealed by Targeted Molecular Dynamics Simulation | 期刊论文 | Liang Qian-Yun;Pang Chun-Li;Li Jun-Wei;Zhang Su-Hua;Liu Hui;Zhan Yong;An Hai-Long |
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