基于热休克蛋白90（HSP90）抑制的三种楝科药用植物中新颖抗肿瘤活性柠檬苦素的发现及作用机制研究
31470416
2014
C0209.植物化学
罗俊
面上项目
教授
中国药科大学
80万元
抗肿瘤;作用机制;楝科;热休克蛋白90;柠檬苦素
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Walrobsins A and B, Two Anti-inflammatory Limonoids from Root Barks of Walsura robusta | 期刊论文 | An Fa-Liang;Sun Dong-Mei;Li Rui-Jun;Zhou Miao-Miao;Yang Ming-Hua;Yin Yong;Kong Ling-Yi;Luo Jun |
| 2 | Limonoids with diverse frameworks from the stem bark of Entandrophragma angolense and their bioactivities | 期刊论文 | Zhang Wen-Yan;An Fa-Liang;Zhou Miao-Miao;Chen Meng-Han;Jian Kai-Li;Quasie Olga;Yang Ming-Hua;Luo Jun;Kong Ling-Yi |
| 3 | Trichiconlides C-F, four new limonoids with 1,2-seco phragmalin-type carbon skeleton from the fruits of Trichilia connaroides | 期刊论文 | An Fa-Liang;Sun Dong-Mei;Wang Xiao-Bing;Yang Lei;Yin Yong;Luo Jun;Kong Ling-Yi |
| 4 | New triterpenoids with diverse side-chains from the barks of Melia Toosendan | 期刊论文 | Hu Ya-Lin;Li Yi;Qiu Lu;Li Jun-He;Heng Li;Wei Shan-Shan;Gao Hong-Liang;Wang Xiao-Bing;Luo Jun;Kong Ling-Yi |
| 5 | Callistiviminenes A-O: Diverse adducts of beta-triketone and sesqui- or monoterpene from the fruits of Callistemon viminalis | 期刊论文 | Wu Lin;Wang Xiao-Bing;Li Rui-Jun;Zhang Ya-Long;Yang Ming-Hua;Luo Jun;Kong Ling-Yi |
| 6 | Ciliatasecones A–C, three rearranged limonoids from Toona ciliata var. yunnanensis | 期刊论文 | Zhang Pan-Pan;Cui Zhi-Rong;Li Yi;Heng Li;Wei Shan-Shan;Wang Xiao-Bing;Yang Ming-Hua;Luo Jun;Kong Ling-Yi |
| 7 | 中药及天然药物活性成分分离新技术研究与应用 | 奖励 | 孔令义;罗俊;王小兵;罗建光;汪俊松;杨鸣华;杨蕾;李意;柳仁民;姚舜 |
| 8 | Two rare limonoids from the stem barks of Entandrophragma utile | 期刊论文 | Luo Jun;Tian Xiao-Meng;Zhang Hong-Jian;Zhou Miao-Miao;Li Jun-He;Kong Ling-Yi |
| 9 | Furan fragment isomerized mexicanolide-type Limonoids from the stem barks of Khaya senegalensis | 期刊论文 | Zhang Wen-Yan;Qiu Lu;Lu Qin-Pei;Zhou Miao-Miao;Luo Jun;Li Yi |
| 10 | Trijugin- and mexicanolide-type limonoids from the fruits of Heynea trijuga that reverse multidrug resistance in MCF-7/DOX cells | 期刊论文 | An Fa-Liang;Sun Dong-Mei;Wang Rui-Zhi;Yang Ming-Hua;Luo Jun;Kong Ling-Yi |
| 11 | Cipadessains A–K, eleven limonoids from the fruits of Cipadessa cinerascens | 期刊论文 | Sun Dong-Mei;An Fa-Liang;Wei Shan-Shan;Zhang Yan-Qiu;Wang Xiao-Bing;Luo Jun;Kong Ling-Yi |
| 12 | Acylphloroglucinols from the fruits of Callistemon viminalis | 期刊论文 | Wu Lin;Zhang Ya-Long;Wang Xiao-Bing;Liu Rui-Huan;Yang Ming-Hua;Kong Ling-Yi;Luo Jun |
| 13 | Sarglaperoxides A and B, Sesquiterpene-Normonoterpene Conjugates with a Peroxide Bridge from the Seeds of Sarcandra glabra | 期刊论文 | Wang Peng;Li Rui-Jun;Liu Rui-Huan;Jian Kai-Li;Yang Ming-Hua;Yang Lei;Kong Ling-Yi;Luo Jun |
| 14 | New Structurally Diverse Limonoids from the Seeds of Khaya senegalensis | 期刊论文 | Tian Xiao-Meng;Li Hui;An Fa-Liang;Li Rui-Jun;Zhou Miao-Miao;Yang Ming-Hua;Kong Ling-Yi;Luo Jun |
| 15 | Limonoids with modified furan rings from root barks of Toona sinensis | 期刊论文 | Li Jun-He;Li Yi;An Fa-Liang;Zhou Miao-Miao;Luo Jie;Jian Kai-Li;Luo Jun;Kong Ling-Yi |
| 16 | Rearranged limonoids with unique 6/5/6/5 tetracarbocyclic skeletons from Toona ciliata and biomimetic structure divergence | 期刊论文 | Luo Jun;Huang Wan-Sha;Hu Sheng-Mou;Zhang Pan-Pan;Zhou Xu-Wei;Wang Xiao-Bing;Yang Ming-Hua;Luo Jian-Guang;Wang Chen;Liu Chang;Yao He-Quan;Zhang Can;Sun Bin;Chen Yi-Jun;Kong Ling-Yi |
| 17 | Anti-inflammatory activity of Khayandirobilide A from Khaya senegalensis via NF-κB, AP-1 and p38 MAPK/Nrf2/HO-1 signaling pathways in lipopolysaccharide-stimulated RAW 264.7 and BV-2 cells | 期刊论文 | Zhou Miao-Miao;Zhang Wen-Yan;Li Rui-Jun;Guo Chao;Wei Shan-Shan;Tian Xiao-Meng;Luo Jun;Kong Ling-Yi |
| 18 | Mexicanolide limonoids with in vitro neuroprotective activities from seeds of Khaya senegalensis | 期刊论文 | Li Hui;Li Yi;Wang Xiao-Bing;Pang Tao;Zhang Lu-Yong;Luo Jun;Kong Ling-Yi |
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