基于大数据的中国人抗体组库量化新方法
31771479
2017
C0608.生物数据资源与分析方法
张镇海
面上项目
教授
南方医科大学
60万元
抗体组库;新方法;下一代测序;人;引物池
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | RAPID: A Rep-Seq Dataset Analysis Platform With an Integrated Antibody Database. | 期刊论文 | Zhang Yanfang;Chen Tianjian;Zeng Huikun;Yang Xiujia;Xu Qingxian;Zhang Yanxia;Chen Yuan;Wang Minhui;Zhu Yan;Lan Chunhong;Wang Qilong;Tang Haipei;Zhang Yan;Wang Chengrui;Xie Wenxi;Ma Cuiyu;Guan Junjie;Guo Shixin;Chen Sen;Yang Wei;Wei Lai;Ren Jian;Yu Xueqing;Zhang Zhenhai |
| 2 | Antibody upstream sequence diversity and its biological implications revealed by repertoire sequencing | 期刊论文 | Zhu Yan;Yang Xiujia;Ma Cuiyu;Tang Haipei;Wang Qilong;Guan Junjie;Xie Wenxi;Chen Sen;Chen Yuan;Wang Minhui |
| 3 | Large-scale analysis of 2,152 Ig-seq datasets reveals key features of B cell biology and the antibody repertoire | 期刊论文 | Yang Xiujia;Wang Minhui;Wu Jiaqi;Shi Dianchun;Zhang Yanfang;Zeng Huikun;Zhu Yan;Lan Chunhong;Deng Yang;Guo Shixin;Xu Lijun;Ma Cuiyu;Zhang Yanxia;Ou Jinxia;Liu Chu-Jun;Chen Yuan;Wang Qilong;Xie Wenxi;Guan Junjie;Ding Jieyu;Wang Zhi;Chang Changqing;Yang Wei;Zhang Huijie;Chen Jun;Qin Lijie;Zhou Hongwei;Bei Jin-Xin;Wei Lai;Cao Guangwen;Yu Xueqing;Zhang Zhenhai |
| 4 | Tools for fundamental analysis functions of TCR repertoires: a systematic comparison | 期刊论文 | Zhang Yanfang;Yang Xiujia;Zhang Yanxia;Zhang Yan;Wang Minhui;Ou Jin Xia;Zhu Yan;Zeng Huikun;Wu Jiaqi;Lan Chunhong;Zhou Hong-Wei;Yang Wei;Zhang Zhenhai |
| 5 | The Biological Significance of Multi-copy Regions and Their Impact on Variant Discovery | 期刊论文 | Sun Jing;Zhang Yanfang;Wang Minhui;Guan Qian;Yang Xiujia;Ou Jin Xia;Yan Mingchen;Wang Chengrui;Zhang Yan;Li Zhi-Hao;Lan Chunhong;Mao Chen;Zhou Hong-Wei;Hao Bingtao;Zhang Zhenhai |
| 6 | Dual UMIs and Dual Barcodes with Minimal PCR Amplification Removes Artifacts and Acquires Accurate Antibody Repertoire | 期刊论文 | Wang Qilong;Zeng Huikun;Zhu Yan;Minhui Wang;Zhang Yanfang;Yang Xiujia;Tang Haipei;Li Hongliang;Chen Yuan;Ma Cuiyu |
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