融合sp3碳氢键官能化过程的去芳香化反应构建手性稠杂环化合物

21978144
2019
B0813.精细化工与专用化学品
李帅帅
面上项目
教授
青岛农业大学
65万元
绿色化学工艺;串联反应;有机小分子催化;立体选择性;不对称合成
2020-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Divergent synthesis of nitrogen heterocycles via H2O-mediated hydride transfer reactions 期刊论文 Fangzhi Hu;Zhipeng Sun;Mengzhe Pan;Liang Wang;Lubin Xu;Xiong-Li Liu;Shuai-Shuai Li
2 基于 α-氢迁移策略构建杂环骨架的研究进展 期刊论文 陈玉琢;孙红梅;王亮;胡方芝;李帅帅
3 Divergent Synthesis of [3,4]-Fused 3‑Alkenyl-Oxindoles via Propargyl Alcohol-Triggered C(sp3)−H Functionalization 期刊论文 Fangzhi Hu;Xinyao Li;Zhanshuai Ding;Liang Wang;Chunyan Ge;Lubin Xu;Shuai-Shuai Li
4 Advances in α-C(sp3)–H functionalization of ethers via cascade [1,n]-hydride transfer/cyclization 期刊论文 Yao-Bin Shen;Fangzhi Hu;Shuai-Shuai Li
5 Controllable construction of pharmaceutically significant scaffolds of 2,3-dihydroquinolin-4-one and benzoazepine-5-one via redox-neutral cascade hydride transfer/cyclization 期刊论文 Ronghao Xie;Shixiao Chen;Yufeng Wang;Xiangcong Yin;Shuai-Shuai Li;Lubin Xu;Liang Wang
6 Facile Construction of 3,4-dihydro-2H-1,2,4-Benzothiadiazine 1,1- Dioxides via Redox-Neutral Cascade Condensation/[1,7]-Hydride Transfer/Cyclization 期刊论文 Yingying Xing;Fengying Dong;Xiangcong Yin;Liang Wang;Shuai-Shuai Li
7 4-羟基香豆素在四氢喹啉及二香豆素内盐合成中的应用(英文) 期刊论文 杨晓宇;柳建林;胡方芝;孙红梅;王亮;李帅帅
8 Fluorinated alcohol mediated N,N '-dialkylation of amino acid derivatives via cascade [1,5]-hydride transfer/cyclization for concise synthesis of tetrahydroquinazoline 期刊论文 Hongjin Shi;Lubin Xu;Didi Ren;Liang Wang;Weisi Guo;Shuai-Shuai Li
9 Switchable construction of oxa-heterocycles with diverse ring sizes via chemoselective cyclization controlled by dibrominated compounds 期刊论文 Fangzhi Hu;Liang Wang;Peng Wang;Zhanshuai Ding;Yuzhuo Chen;Lubin Xu;Xiong-Li Liu;Shuai-Shuai Li
10 一种氧气促进的去芳香化反应在构建螺环二烯酮骨架中的应用 专利 李帅帅;胡方芝;李鑫瑶
11 Redox-triggered dearomative [5 + 1] annulation of indoles with O-alkyl ortho-oxybenzaldehydes for the synthesis of spirochromanes 期刊论文 Lianyi Cao;Fangzhi Hu;Hongmei Sun;Xiaomei Zhang;Shuai-Shuai Li
12 一种氧化吲哚螺烯丙基取代色满骨架及其制备方法 专利 胡方芝;李帅帅;杜昭
13 Aromatization-driven cascade [1,5]-hydride transfer/cyclization for synthesis of spirochromanes 期刊论文 Lianyi Cao;Fangzhi Hu;Jiacheng Dong;Xiao-Mei Zhang;Shuai-Shuai Li
14 Controllable Synthesis of N-Heterocycles via Hydride Trans-fer Strategy-enabled Formal [5+1] and [5+2] Cyclizations 期刊论文 Ying Dong;Fangzhi Hu;Huixin Wu;Feng-Wei Guo;Liang Wang;Feng-Yu Du;Shuai-Shuai Li
15 Alkyl amines and ethers as traceless hydride donors in [1,5]-hydride transfer cascade reactions 期刊论文 Yao-Bin Shen;Fangzhi Hu;Shuai-Shuai Li
16 The dual alkylation of the C(sp3)–H bond of cyclic α-methyl-N-sulfonyl imines via the sequential condensation/hydride transfer/cyclization process 期刊论文 Kejin Yuan;Fengying Dong;Xiangcong Yin;Shuai-Shuai Li;Liang Wang;Lubin Xu
17 Hydrogen-bonding-assisted redox-neutral construction of tetrahydroquinolinesviahydride transfer 期刊论文 Xiaoyu Yang;Fangzhi Hu;Liang Wang;Lubin Xu;Shuai-Shuai Li
18 Aromatization-driven deconstruction/refunctionalization of unstrained rings 期刊论文 Fangzhi Hu;Liang Wang;Lubin Xu;Shuai-Shuai Li
19 Facile syntheses of tetrahydroquinolines and 1,2-dihydroquinolines via vinylogous cascade hydride transfer/cyclization 期刊论文 Mengzhu Guo;Fengying Dong;Xiangcong Yin;Lubin Xu;Liang Wang;Shuai-Shuai Li
20 Hydride transfer enabled switchable dearomatization of indoles in the carbocyclic ring and the pyrrole ring 期刊论文 Kang Duan;Hongjin Shi;Lin-Xuan Wang;Shuai-Shuai Li;Lubin Xu;Jian Xiao
21 Divergent α-Functionalization of Cyclic Amines via Ring Construction by Molecular O2 Oxidized Dearomatization and Ring Deconstruction by Aromatization Driven C-C σ-Bond Cleavage 期刊论文 Fangzhi Hu;Liang Wang;Chunyan Ge;Xinyao Li;Zhanshuai Ding;Lubin Xu;Shuai-Shuai Li
22 Controllable Synthesis of N-Containing and O-Containing Heterocycles via Formal [3+2] and [5+2] Cyclizations 期刊论文 Zhipeng Sun;Ranran Hou;Shuai-Shuai Li;Xinyu Wang;Liang Wang;Fangzhi Hu;Feng-Wei Guo
23 Chemoselective and diastereoselective construction of 4-alkylidene-tetrahydroquinoline via a redox-neutral vinylogous cascade [1,7]-hydride transfer/6-endo-trig cyclization strategy 期刊论文 Yufeng Wang;Qiang Li;Xiaopei Song;Jing Wang;Xiangcong Yin;Shuai-Shuai Li;Liang Wang
24 Diastereoselective construction of structurally diverse 2,3-dihydroquinolin-4-one scaffolds via redox neutral cascade [1,7]-hydride transfer/cyclization 期刊论文 Ronghao Xie;Shixiao Chen;Xianping Xiang;Xiangcong Yin;Lubin Xu;Shuai-Shuai Li;Liang Wang;Fengying Dong
25 氮杂环化合物的绿色精准合成--山东化学化工科学技术奖三等奖 奖励 李帅帅;王亮;胡方芝;徐鲁斌
26 Divergent syntheses of spirooxindoles from oxindole-embedded four-membered synthon via cycloaddition reactions 期刊论文 Hongjin Shi;Liang Wang;Shuai-Shuai Li;Yongjun Liu;Lubin Xu
27 Merging dearomatization with redox-neutral C(sp3)–H functionalization via hydride transfer/ cyclization: recent advances and perspectives 期刊论文 Fangzhi Hu;Yao-Bin Shen;Liang Wang;Shuai-Shuai Li
28 Redox-Triggered Switchable Synthesis of 3,4-Dihydroquinolin-2(1H)-one Derivatives via Hydride Transfer/N-Dealkylation/N-Acylation 期刊论文 Xiaoyu Yang;Liang Wang;Fangzhi Hu;Lubin Xu;Sanming Li;Shuai-Shuai Li
29 HFIP-mediated three-component imidization of electron-rich arenes with in situ formed spiroindolenines for facile construction of 2-arylspiroindolenines 期刊论文 Chunyan Ge;Liang Wang;Fangzhi Hu;Zhanshuai Ding;Xinyao Li;Deshuai Xiao;Jiayi Wang;Shuai-Shuai Li
30 一种双香豆素内盐生物活性骨架的绿色合成方法及应用 专利 李帅帅;胡方芝;王亮;徐鲁斌;杨晓宇
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