组蛋白分子伴侣FACT对染色质结构及基因功能调控的分子机制研究
31871290
2018
C0601.遗传物质结构与功能
陈萍
面上项目
教授
中国科学院生物物理研究所
60万元
分子机制;基因调控;组蛋白伴侣FACT;人类;染色质结构
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs | 期刊论文 | Yang Yang;Liwei Zhang;Chaoyang Xiong;Jun Chen;Li Wang;Zengqi Wen;Juan Yu;Ping Chen;Yanhui Xu;Jingji Jin;Yong Cai;Guohong Li |
| 2 | Curaxin-Induced DNA Topology Alterations Trigger the Distinct Binding Response of CTCF and FACT at the Single-Molecule Level | 期刊论文 | Lu Ke;Liu Cuifang;Liu Yinuo;Luo Anfeng;Chen Jun;Lei Zhichao;Kong Jingwei;Xiao Xue;Zhang Shuming;Wang Yi-Zhou;Ma Lu;Dou Shuo-Xing;Wang Peng-Ye;Li Ming;Li Guohong;Li Wei;Chen Ping |
| 3 | H2A mono-ubiquitination differentiates FACT's functions in nucleosome assembly and disassembly. | 期刊论文 | Wang Yi-Zhou;Liu Cuifang;Zhao Jicheng;Yu Juan;Luo Anfeng;Xiao Xue;Dou Shuo-Xing;Ma Lu;Wang Peng-Ye;Li Ming;Li Guohong;Yan Jianbin;Chen Ping;Li Wei |
| 4 | Structures and Functions of Chromatin Fibers | 期刊论文 | Chen Ping;Li Wei;Li Guohong |
| 5 | Histone H2A Ubiquitination Reinforces Mechanical Stability and Asymmetry at the Single-Nucleosome Level. | 期刊论文 | Xiao Xue;Liu Cuifang;Pei Yingxin;Wang Yi-Zhou;Kong Jingwei;Lu Ke;Ma Lu;Dou Shuo-Xing;Wang Peng-Ye;Li Guohong;Chen Ping;Li Wei |
| 6 | Rett syndrome-causing mutations compromise MeCP2-mediated liquid-liquid phase separation of chromatin | 期刊论文 | Wang Liang;Hu Mingli;Zuo Meiqing;Zhao Jicheng;Wu Di;Huang Li;Wen Yongxin;Li Yunfan;Chen Ping;Bao Xinhua;Dong Mengqiu;Li Guohong;Li Pilong |
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