IGFBPrP1在致肝纤维化形成中对肝星状细胞自噬的调节机制

81670559
2016
H0310.肝损伤、修复与再生
刘立新
面上项目
主任医师
山西医科大学
51万元
肝脏;mTOR;肝星状细胞;自噬;IGFBPrP1
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The lncRNA NEAT1/miR-29b/Atg9a axis regulates IGFBPrP1-induced autophagy and activation of mouse hepatic stellate cells 期刊论文 Yangyang Kong;Tingjuan Huang;Haiyan Zhang;Qianqian Zhang;Junjie Ren;Xiaohong Guo;Huiqin Fan;Lixin Liu
2 IGFBPrP1 accelerates autophagy and activation of hepatic stellate cells via mutual regulation between H19 and PI3K/AKT/mTOR pathway 期刊论文 Tingjuan Huang;Junjie Ren;Qianqian Zhang;Yangyang Kong;Haiyan Zhang;Xiaohong Guo;Huiqin Fan;Lixin Liu
3 IGFBPrP1通过TGFβ1及其相关信号通路致肝纤维化作用的临床意义 奖励 刘立新;郭晓红;张海燕;张骞骞;范慧琴;任俊杰;黄婷娟;孔洋洋
4 Insulin-like growth factor binding protein-related protein 1 activates primary hepatic stellate cells via autophagy regulated by the PI3K/Akt/mTOR signaling pathway 期刊论文 Yuzheng Zhou;Qianqian Zhang;Yangyang Kong;Xiaohong Guo;Haiyan Zhang;Huiqin Fan;Lixin Liu
5 Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice 期刊论文 Junjie Ren;Tingjuan Huang;Qianqian Zhang;Haiyan Zhang;Xiaohong Guo;Huiqin Fan;Renke Li;Lixin Liu
6 Kidney and lung tissue modifications after BDL-induced liver injury in mice are associated with increased expression of IGFBPrP1 and activation of the NF-κB inflammation pathway 期刊论文 Zhihui Hu;Yangyang Kong;Junjie Ren;Tingjuan Huang;Yanqin Wang;Lixin Liu
7 Value of IGFBPrP1 and contrast-enhanced ultrasound in liver fibrosis staging with rabbits 期刊论文 Haiyan Zhang;Yun Zhang;Xinghua Wang;Xiaohong Guo;Huiqin Fan;Tingting Lv;Lixin Liu
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