须糖多孢菌丁烯基多杀菌素生物合成的调控网络及重要基因元件优化
31770106
2017
C2102.合成生物学与生物改造技术
夏立秋
面上项目
教授
湖南师范大学
60万元
丁烯基多杀菌素;代谢网络模型;基因删除;须糖多孢菌;基因元件优化
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | GlnA基因对刺糖多孢菌生长发育及多杀菌素合成的影响 | 期刊论文 | 肖洁;刘朱东;彭胜男;何昊城;穰杰;刘熊;丁学知;夏立秋 |
| 2 | 须糖多孢菌功能基因组研究 | 会议论文 | 穰杰;何昊城;唐建立;刘朱东;苑爽芹;彭胜男;孙运军;夏立秋 |
| 3 | Effect of the TetR family transcriptional regulator Sp1418 on the global metabolic network of Saccharopolyspora pogona | 期刊论文 | He Haocheng;Yuan Shuangqin;Hu Jinjuan;Chen Jianming;Rang Jie;Tang Jianli;Liu Zhudong;Xia Ziyuan;Ding Xuezhi;Hu Shengbiao;Xia Liqiu |
| 4 | Deciphering the Metabolic Pathway Difference Between Saccharopolyspora pogona and Saccharopolyspora spinosa by Comparative Proteomics and Metabonomics | 期刊论文 | Rang Jie;He Haocheng;Yuan Shuangqin;Tang Jianli;Liu Zhudong;Xia Ziyuan;Khan Tahir Ali;Hu Shengbiao;Yu Ziquan;Hu Yibo;Sun Yunjun;Huang Weitao;Ding Xuezhi;Xia Liqiu |
| 5 | 一株tetR26169基因敲除的须糖多孢菌工程菌株及其应用 | 专利 | 何思颖;柏丹;夏伦;万千千;夏立秋;穰杰;何昊城 |
| 6 | Flaviolin-Like Gene Cluster Deletion Optimized the Butenyl-Spinosyn Biosynthesis Route in Saccharopolyspora pogona. | 期刊论文 | He Haocheng;Tang Jianli;Chen Jianming;Hu Jinjuan;Zhu Zirong;Liu Yang;Shuai Ling;Cao Li;Liu Zhudong;Xia Ziyuan;Ding Xuezhi;Hu Shengbiao;Zhang Youming;Rang Jie;Xia Liqiu |
| 7 | fcl基因对须糖多孢菌丁烯基多杀菌素生物合成及生长发育的影响 | 期刊论文 | 彭胜男;何昊城;苑爽芹;穰杰;胡胜标;孙运军;余子全;黄伟涛;胡益波;丁学知;夏立秋 |
| 8 | SenX3-RegX3, an Important Two-Component System, Regulates Strain Growth and Butenyl-spinosyn Biosynthesis in Saccharopolyspora pogona | 期刊论文 | Jie Rang;Haocheng He;Jianming Chen;Jinjuan Hu;Jianli Tang;Zhudong Liu;Ziyuan Xia;Xuezhi Ding;Youming Zhang;Liqiu Xia |
| 9 | 一株须糖多孢菌丁烯基多杀菌素高产突变株 | 专利 | 夏立秋;罗林根;杨燕;丁学知 |
| 10 | Effects of acuC on the growth development and spinosad biosynthesis of Saccharopolyspora spinosa. | 期刊论文 | Liu Zhudong;Xiao Jie;Tang Jianli;Liu Yang;Shuai Ling;Cao Li;Xia Ziyuan;Ding Xuezhi;Rang Jie;Xia Liqiu |
| 11 | 一株浅黄霉素基因簇敲除的须糖多孢菌工程菌株及其应用 | 专利 | 夏立秋;何昊城;穰杰;丁学知 |
| 12 | 一株须糖多孢菌ΔClu13-MmsA及其构建方法与应用 | 专利 | 夏立秋;何昊城;丁学知;穰杰 |
| 13 | 通过两种糖多孢菌属菌株原生质体融合提高多杀菌素产量研究 | 期刊论文 | 易卓;夏立秋;丁学知;胡胜标;罗玉双;王海龙;唐滢;黄鑫 |
| 14 | Identification of a TetR family regulator and a polyketide synthase gene cluster involved in growth development and butenyl-spinosyn biosynthesis of Saccharopolyspora pogona | 期刊论文 | Jie Rang;Zirong Zhu;Yunlong Li;Li Cao;Haocheng He;Jianli Tang;Jinjuan Hu;Jianming Chen;Shengbiao Hu;Weitao Huang;Ziquan Yu;Xuezhi Ding;Yunjun Sun;Qingji Xie;Liqiu Xia |
| 15 | 不同碳源对须糖多孢菌生长发育及丁烯基多杀菌素生物合成的影响 | 期刊论文 | 何思颖;柏丹;夏伦;万千千;罗粤雯;夏立秋 |
| 16 | RNA-Seq-Based Transcriptomic Analysis of Saccharopolyspora spinosa Revealed the Critical Function of PEP Phosphonomutase in the Replenishment Pathway. | 期刊论文 | Liu Zhudong;Zhu Zirong;Tang Jianli;He Haocheng;Wan Qianqian;Luo Yuewen;Huang Weitao;Yu Ziquan;Hu Yibo;Ding Xuezhi;Xia Liqiu |
| 17 | Deletion of a hybrid NRPS-T1PKS biosynthetic gene cluster via Latour gene knockout system in Saccharopolyspora pogona and its effect on butenyl-spinosyn biosynthesis and growth development. | 期刊论文 | Rang Jie;Li Yunlong;Cao Li;Shuai Ling;Liu Yang;He Haocheng;Wan Qianqian;Luo Yuewen;Yu Ziquan;Zhang Youming;Sun Yunjun;Ding Xuezhi;Hu Shengbiao;Xie Qingji;Xia Liqiu |
| 18 | 一株cspA基因加倍的须糖多孢菌工程菌株及其应用 | 专利 | 夏立秋;穰杰;何昊城;丁学知;孙运军 |
| 19 | Impact on strain growth and butenyl-spinosyn biosynthesis by overexpression of polynucleotide phosphorylase gene in Saccharopolyspora pogona | 期刊论文 | Li Li;Rang Jie;He Haochen;He Siying;Liu Zhudong;Tang Jianli;Xiao Jie;He Lian;Hu Shengbiao;Yu Ziquan;Ding Xuezhi;Xia Liqiu |
| 20 | Bacterioferritin: a key iron storage modulator that affects strain growth and butenyl-spinosyn biosynthesis in Saccharopolyspora pogona. | 期刊论文 | Tang Jianli;Zhu Zirong;He Haocheng;Liu Zhudong;Xia Ziyuan;Chen Jianming;Hu Jinjuan;Cao Li;Rang Jie;Shuai Ling;Liu Yang;Sun Yunjun;Ding Xuezhi;Hu Shengbiao;Xia Liqiu |
| 21 | PadR对须糖多孢菌丁烯基多杀菌素生物合成及转运相关蛋白表达的影响 | 期刊论文 | 何思颖;柏丹;夏伦;万千千;罗粤雯;邱玉玲;夏立秋 |
| 22 | 基于线性片段同源重组进行须糖多孢菌基因簇阻断的方法 | 专利 | 夏立秋;穰杰;何昊城;丁学知;孙运军 |
| 23 | Comparative Proteomics Reveals the Effect of the Transcriptional Regulator Sp13016 on Butenyl-Spinosyn Biosynthesis in Saccharopolyspora pogona. | 期刊论文 | Tang Jianli;He Haocheng;Li Yunlong;Liu Zhudong;Xia Ziyuan;Cao Li;Zhu Zirong;Shuai Ling;Liu Yang;Wan Qianqian;Luo Yuewen;Zhang Youming;Rang Jie;Xia Liqiu |
| 24 | LytSR和PdtaSR双组分系统对须糖多孢菌丁烯基多杀菌素生物合成的影响 | 期刊论文 | 万千千;罗粤雯;何昊城;夏梓源;穰杰;朱梓榕;曹丽;夏立秋 |
| 25 | AfsR is an important regulatory factor for growth and butenyl-spinosyn biosynthesis of Saccharopolyspora pogona | 期刊论文 | Li Li;Gong Liang;He Haocheng;Liu Zhudong;Rang Jie;Tang Jianli;Peng Shengnan;Yuan Shuangqin;Ding Xuezhi;Yu Ziquan;Xia Liqiu;Sun Yunjun |
| 26 | 一株刺糖多孢菌多杀菌素高产工程菌株及其应用 | 专利 | 夏立秋;杨燕;丁学知;胡胜标 |
| 27 | Effects of lytS-L on the primary metabolism and butenyl-spinosyn biosynthesis in Saccharopolyspora pogona | 期刊论文 | Haocheng He;Shengnan Peng;Shuangqin Yuan;Jianli Tang;Zhudong Liu;Jie Rang;Ziyuan Xia;Jinjuan Hu;Jianming Chen;Xuezhi Ding;Shengbiao Hu;Yunjun Sun;Liqiu Xia |
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