【31190063】细胞迁移的在体多维显微成像与蛋白活性光学操纵技术研究及应用国家自然基金项目

细胞迁移的在体多维显微成像与蛋白活性光学操纵技术研究及应用

项目批准号： 31190063

批准年份： 2011

学科分类： C0706.细胞极性与细胞运动

项目负责人：欧光朔

资助类别：重大项目

负责人职称：教授

依托单位：清华大学

资助金额： 390万元

关键词：活体显微成像技术；细胞迁移；微环境；细胞极性；神经发育

起止时间： 2012-01至2016-12

中英文摘要
结题摘要
结题报告
项目成果
项目参与人

查看更多信息请先登录或注册

序号	标题	类型	作者
1	Live imaging of cellular dynamics during Caenorhabditis elegans postembryonic development	期刊论文	Guoxin Feng\|Yihong Yang\|Xiangming Wang\|Guangshuo Ou\|
2	SomaticCRISPR-Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia	期刊论文	Wenjing Li\|Penshan Yi\|Guangshuo Ou\|
3	TBCK Influences Cell Proliferation, Cell Size and mTOR Signaling Pathway	期刊论文	Liu Yueli;Yan Xiaoyi;Zhou Tianhua
4	MiR-215 modulates gastric cancer cell proliferation by targeting RB1	期刊论文	Xiaojia Wang\|Yibin Kang\|Jianmin Si\|Tianhua Zhou\|
5	Developmental stage-dependent transcriptional regulatory pathways control neuroblast lineage progression	期刊论文	Ze Cheng\|Xiangming Wang\|Wei Li\|Guangshuo Ou\|
6	NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1	期刊论文	Zhu, Xueliang\|Liu, Wei\|Yang, Yuehong\|Zhou, Tianhua\|
7	The heparan sulfate-modifying enzyme glucuronyl C5-epimerase HSE-5 controls Caenorhabditis elegans Q neuroblast polarization during migration.	期刊论文	Xiangming Wang;Jianhong Liu;Zhiwen Zhu;Guangshuo Ou
8	Conditional targeted genome editing using somatically expressed TALENs in C. elegans	期刊论文	Xing Liang\|Zhiwen Zhu\|Wei Li\|Guangshuo Ou\|
9	Anillin Regulates Neuronal Migration and Neurite Growth by Linking RhoG to the Actin Cytoskeleton	期刊论文	Yan Zhang\|Zhucheng Chen\|Shanjin Huang\|Guangshuo Ou\|
10	Apoptotic regulators promote cytokinetic midbody degradation in C. elegans	期刊论文	Guoxin Feng\|Ze Cheng\|Wei Li\|Guangshuo Ou\|
11	The application of transcription activator-like effector nucleases for genome editing in C. elegans	期刊论文	Yi Peishan;Li Wei;Ou Guangshuo
12	Conditional Knockouts Generated by Engineered CRISPR-Cas9 Endonuclease Reveal the Roles of Coronin in C. elegans Neural Development	期刊论文	Zhongfu Shen;Xianliang Zhang;Yongping Chai;Zhiwen Zhu;Peishan Yi;Guoxin Feng;Wei Li;Guangshuo Ou
13	Transmembrane protein MIG-13 links the Wnt signaling and Hox genes to the cell polarity in neuronal migration	期刊论文	Yihong Yang\|Guoxin Feng\|Wei Li\|Guangshuo Ou\|
14	发色基团辅助激光失活技术的研究方法及其应用进展	期刊论文	豆敏华\|张家瑜\|周天华\|
15	Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications	期刊论文	Jin, Juan\|Xu, Xiao\|Zhuo, Wei\|Zhou, Tian-Hua\|
16	Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes	期刊论文	Yuehong Yang\|Xiaoyi Yan\|Xiaoqi Liu\|Tianhua Zhou\|
17	Stereotyped distribution of midbody remnants in early C. elegans embryos requires cell death genes and is dispensable for development	期刊论文	Ou, Guangshuo\|Gentili, Christian\|Gonczy, Pierre\|
18	The glial actin cytoskeleton regulates neuronal ciliogenesis.	期刊论文	Li, Wei\|Miao, Long\|Zhang, Yan\|Ou, Guangshuo\|
19	The application of somatic CRISPR-Cas9 to conditional genome editing in Caenorhabditis elegans.	期刊论文	Li, Wei\|Ou, Guangshuo\|
20	Snail-Regulated MiR-375 Inhibits Migration and Invasion of Gastric Cancer Cells by Targeting JAK2	期刊论文	Xu Yanjun;Jin Juan;Liu Yiman;Huang Zhenxia;Deng Yujie;You Tao;Zhou Tianhua;Si Jianmin;Zhuo Wei
21	A proneural gene controls C. elegans neuroblast asymmetric division and migration	期刊论文	Dong Tian\|Yongping Chai\|Wei Li\|Guangshuo Ou\|
22	Chromophore-assisted laser inactivation in neural development	期刊论文	Wei Li\|Nico Stuurman\|Guangshuo Ou\|
23	Functional Coordination of WAVE and WASP in C.elegans Neuroblast Migration	期刊论文	Jia-Wei Wu\|Zhi-Xin Wang\|Shanjin Huang\|Guangshuo Ou\|
24	Emerging roles of NudC family: from molecular regulation to clinical implications	期刊论文	Fu, Qiqin\|Wang, Wei\|Zhou, Tianhua\|Yang, Yuehong\|
25	Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell	期刊论文	Dong Tian\|Xiaochen Wang\|Ronald D. Vale\|Guangshuo Ou\|

查看更多信息请先登录或注册

再问科研

相关项目

趋势报告

经验分享