整合素蛋白N-糖链介导的膜功能复合物对癌细胞增殖和浸润的调控及其作用机制的研究

31670807
2016
C0506.糖、脂生物化学
jianguo gu
面上项目
教授
南通大学
65万元
增殖;肿瘤;N-糖链;膜蛋白复合物;整合素
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system 期刊论文 Chengwei Duan;Tomohiko Fukuda;Tomoya Isaji;Feng Qi;Jie Yang;Yuqin Wang;Shinichiro Takahashi;Jianguo Gu
2 O-GlcNAcylation regulates integrin-mediated cell adhesion and migration via formation of focal adhesion complexes. 期刊论文 Zhiwei Xu;Tomoya Isaji;Tomohiko Fukuda;Yuqin Wang;Jianguo Gu
3 ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins. 期刊论文 Feng Qi;Tomoya Isaji;Chengwei Duan;Jie Yang;Yuqin Wang;Tomohiko Fukuda;Jianguo Gu
4 Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation 期刊论文 Yuqin Wang;Jinge Wei;Mengjue Tu;Jianguo Gu;Wei Zhang
5 A complex between phosphatidylinositol 4 kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells. 期刊论文 Tomoya Isaji;Sanghun Im;Akihiko Kameyama;Yuqin Wang;Tomohiko Fukuda;Jianguo Gu
6 Deficiency of α1,6-fucosyltransferase promotes neuroinflammation by increasing the sensitivity of glial cells to inflammatory mediators 期刊论文 Xu Lu;Dongmei Zhang;Hayato Shoji;Chengwei Duan;Guowei Zhang;Tomoya Isaji;Yuqin Wang;Tomohiko Fukuda;Jianguo Gu
7 A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin alpha 5 for Cell Migration 期刊论文 Hang Qinglei;Isaji Tomoya;Hou Sicong;Wang Yuqin;Fukuda Tomohiko;Gu Jianguo
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