基于肾周脂肪棕色化-SIRT1-HO-1/脂联素轴正反馈环路探讨Irisin保护肥胖相关性肾病的研究

81870593
2018
H0709.能量代谢调节异常与肥胖
孙晓东
面上项目
主任医师
潍坊医学院
57万元
肾周脂肪棕色化;血红素加氧酶-1;Irisin;血管周围脂肪;肥胖相关性肾病
2019-01-01到2022-12-31
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序号 标题 类型 作者
1 Transcriptomic Analysis Reveals the Protective Effects of Empagliflozin on Lipid Metabolism in Nonalcoholic Fatty Liver Disease 期刊论文 Yuting Ma;Chengxia Kan;Hongyan Qiu;Yongping Liu;Ningning Hou;Fang Han;Junfeng Shi;Xiaodong Sun
2 COL1A1: A novel oncogenic gene and therapeutic target in malignancies 期刊论文 Xue Li;Xiaodong Sun;Chengxia Kan;Bing Chen;Na Qu;Ningning Hou;Yongping Liu;Fang Han
3 Empagliflozin activates Sestrin2-mediated AMPK/mTOR pathway and ameliorates lipid accumulation in obesity-related nonalcoholic fatty liver disease 期刊论文 Yuting Ma;Guangdong Zhang;Zenggguang Kuang;Qian Xu;Tongtong Ye;Xue Li;Na Qu;Fang Han;Chengxia Kan;Xiaodong Sun
4 Global Burden of cardiomyopathy and myocarditis in the older adults from 1990 to 2019 期刊论文 Kexin Zhang;Xuebing Cheng;Na Qu;Hongwei Song;Youhong Luo;Tongtong Ye;Qian Xu;Hongzhan Tian;Chengxia Kan;Ningning Hou
5 继发于2型糖尿病的暴发性1型糖尿病的临床诊治并文献复习 期刊论文 鲍亚慧;徐茜;刘芳;张阳;曹志斌;曲俊生;孙晓东;惠宗光
6 The promotion of active aging through older adult education in the context of population aging 期刊论文 Kexin Zhang;Chengxia Kan;Youhong Luo;Hongwei Song;Zhenghui Tian;Wenli Ding;Linfei Xu;Fang Han;Ningning Hou
7 Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice. 期刊论文 Xiaodong Sun;Fang Han;Qingguo Lu;Xuan Li;Di Ren;Jingwen Zhang;Ying Han;Yang K Xiang;Ji Li
8 Empagliflozin ameliorates obesity associated fatty liver disease by regulating Sestrin2-mediated AMPK-mTOR signalling pathway in obese mice 会议论文 Sun X.;Hou N.;Han F.;Liu Y.;Huang N.
9 Liraglutide improves nonalcoholic fatty liver disease by regulation of sestrin2-mediated activation of AMPK/Nrf2/HO-1 pathway in obese mice 会议论文 Han X;Han F;Pan R;Hou N;Liu Y;Sun X
10 DL-3-n-butylphthalide protects H9c2 cardiomyoblasts from ischemia/reperfusion injury by regulating HSP70 expression via PI3K/AKT pathway activation 期刊论文 Yunchen Yu;Yuying Zhu;Xiaotong Sun;Yongxing Li;Mingling Wang;Bin Dong;Xiaodong Sun;Wenming Hou
11 Novel insight into perirenal adipose tissue: A neglected adipose depot linking cardiovascular and chronic kidney disease 期刊论文 Na Huang;Enwen Mao;Ningning Hou;Yongping Liu;Fang Han;Xiaodong Sun
12 Liraglutide improves obesity-induced renal injury by alleviating uncoupling of the glomerular VEGF-NO axis in obese mice 期刊论文 Kai Li;Jinhong Sun;Na Huang;Yuting Ma;Fang Han;Yongping Liu;Ningning Hou;Xiaodong Sun
13 Relationships Between Perivascular Adipose Tissue and Abdominal Aortic Aneurysms 期刊论文 Tongtong Ye;Guangdong Zhang;Hangyu Liu;Junfeng Shi;Hongyan Qiu;Yongping Liu;Fang Han;Ningning Hou
14 The Therapeutic Potential of Mesenchymal Stem Cells in the Treatment of Diabetes Mellitus 期刊论文 Liang Zhu;Sheng Wang;JunSheng Qu;Zongguang Hui;Chengxia Kan;Ningning Hou;Xiaodong Sun
15 Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway 期刊论文 Xue Han;CHuanhua Ding;Guangdong Zhang;RuiYan Pan;Yongping Liu;Na Huang;Ningning Hou;Fang Han;Wenjie Xu;Xiaodong Sun
16 Relationship between serum Dickkopf-1 and albuminuria in patients with type 2 diabetes 期刊论文 Ningning Hou;Chengxia Kan;Na Huang;Yongping Liu;Enwen Mao;Yuting Ma;Fang Han;Hongxi Sun;Xiaodong Sun
17 Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells 期刊论文 Na Qu;Junsheng Qu;Na Huang;Kexin Zhang;Tongtong Ye;Junfeng Shi;Bing Chen;Chengxia Kan;Jingwen Zhang;Fang Han;Ningning Hou;Xiaodong Sun;Ruiyan Pan
18 Association between serum Sestrin2 level and diabetic peripheral neuropathy in type 2 diabetic patients 期刊论文 Enwen Mao;Xuebing Cheng;Wenchao Li;Chengxia Kan;Na Huang;Hongsheng Wang;Ningning Hou;Xiaodong Sun
19 Empagliflozin-induced gut microbiota alternation reduces obesity in high-fat diet-fed mice 会议论文 Shi J;Qiu H;Hou N;Liu Y;Han F;Kan C;Sun X
20 Decreased shedding dipeptidyl peptidase 4 from membrane in Hashimoto's thyroiditis 期刊论文 Wenjie Xu;Yongping Liu;Xuebing Cheng;Na Huang;Ningning Hou;Hongsheng Wang;Fang Han;Xue Han;Xiaodong Sun
21 The protective effects of SGLT-2 inhibitors, GLP-1 receptor agonists, and RAAS blockers against renal injury in patients with type 2 diabetes 期刊论文 Zengguang Kuang;Ningning Hou;Chengxia Kan;Fang Han;Hongyan Qiu;Xiaodong Sun
22 Relationship between circulating sestrin2 level and diabetic peripheral neuropathy in type 2 diabetic patients 会议论文 Sun X;Han F;Mao E;Kan C;Hou N
23 Editorial: The Impact of Adipose Tissue Dysfunction on Cardiovascular and Renal Disease 期刊论文 Xiaodong Sun;Cheng-Chao Ruan;Alexandre A. da Silva
24 Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice 期刊论文 Fang Han;Chengxia Kan;Di Wu;Zengguang Kuang;Hongwei Song;Youhong Luo;Le Zhang;Ningning Hou;Xiaodong Sun
25 Liraglutide improves vascular dysfunction by regulating a cAMP-independent PKA-AMPK pathway in perivascular adipose tissue in obese mice. 期刊论文 Fang Han;Ningning Hou;Yongping Liu;Na Huang;Ruiyan Pan;Xing Zhang;Enwen Mao;Xiaodong Sun
26 Editorial: The link between metabolic syndrome and chronic kidney disease: Focus on diagnosis and therapeutics 期刊论文 Ningning Hou;Congjuan Luo;Guiting Lin
27 Comprehensive overview of human serum albumin glycation in diabetes mellitus 期刊论文 Hongyan Qiu;Ningning Hou;Junfeng Shi;Yongping Liu;Chengxia Kan;Fang Han;Xiaodong Sun
28 The Relationship Between circulating Dickkopf-1 levels and urine albumin excretion in Type 2 Diabetic Patients 会议论文 Mao E;Kan C;Hou N;Huang N;Liu Y;Han F;Sun X
29 Mortality Risk of Antidiabetic Agents for Type 2 Diabetes With COVID-19: A Systematic Review and Meta-Analysis 期刊论文 Chengxia Kan;Yang Zhang;Fang Han;Qian Xu;Tongtong Ye;Ningning Hou;Xiaodong Sun
30 Doctor of Public Health-Crisis Management and COVID-19 Prevention and Control: A Case Study in China 期刊论文 Weiqin Cai;Runguo Gao;Qi Jing;Chunping Wang;Ningning Hou;Weide Liu;Qianqian Gao;Xiaodong Sun
31 Integrated multi-omics analyses reveal effects of empagliflozin on intestinal homeostasis in high-fat diet mice 期刊论文 Junfeng Shi;Hongyan Qiu;Qian Xu;Yuting Ma;Tongtong Ye;Zengguang Kuang;Na Qu;Chengxia Kan;Ningning Hou;Fang Han;Xiaodong Sun
32 Empagliflozin ameliorates obesity-induced cardiac dysfunction via activating SIRT3-mediated autophagy 会议论文 Zhang J;Hou N;Han F;Ma Y;Ye T;Sun X
33 Empagliflozin improves obesity-related heart failure with preserved ejection fraction by Sestrin2-mediated AMPK activation and antioxidant system in obese mice 会议论文 Sun X;Han F;Li X;Li J
34 Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1–Adiponectin Axis 期刊论文 Tongtong Ye;Jingwen Zhang;Di Wu;Junfeng Shi;Zengguang Kuang;Yuting Ma;Qian Xu;Bing Chen;Chengxia Kan;Xiaodong Sun;Fang Han
35 Novel HNF1A gene mutation in maturity-onset diabetes of the young: A case report 期刊论文 Qian Xu;Chengxia Kan;Ningning Hou;Xiaodong Sun
36 A Meta-Analysis of Pregnancy Outcomes With Levothyroxine Treatment in Euthyroid Women With Thyroid Autoimmunity 期刊论文 Xiaodong Sun;Ningning Hou;Hongsheng Wang;Lin Ma;Jinhong Sun;Yongping Liu
37 Post-Translational Modifications of p53 in Ferroptosis: Novel Pharmacological Targets for Cancer Therapy 期刊论文 Le Zhang;Ningning Hou;Bing Chen;Chengxia Kan;Fang Han;Jingwen Zhang;Xiaodong Sun
38 Comprehensive Analysis of Tumor Immune Microenvironment and Prognosis of m6A-Related lncRNAs in Lung Adenocarcinoma 期刊论文 Yangyang Shen;Ningning Hou;Fang Han;Bing Chen;Junfeng Shi;Xiaodong Sun
39 Growth differentiation factor 11: a "rejuvenation factor" involved in regulation of age-related diseases? 期刊论文 Yuting Ma;Yongping Liu;Fang Han;Hongyan Qiu;Junfeng Shi;Na Huang;Ningning Hou;Xiaodong Sun
40 Irisin protects against obesity-related kidney disease by regulating perirenal adipose tissue function in obese mice 会议论文 Sun X;Han F;Kan C;Hou N
41 Liraglutide improves obese-induced renal injury by alleviating uncoupling of glomerular VEGF-NO axis in obese mice 会议论文 Ma Y.;Li K.;Hou N.;Han F.;Han X.;Sun X.
42 Empagliflozin attenuates obesity-related kidney dysfunction and NLRP3 inflammasome activity through the HO-1/adiponectin axis 会议论文 Ye T;Zhang J;Shi J;Kan C;Han F;Hou N;Sun X
43 Thyroid Cancer and COVID-19: Prospects for Therapeutic Approaches and Drug Development 期刊论文 Na Qu;Zongguang Hui;Zhixin Shen;Chengxia Kan;Ningning Hou;Xiaodong Sun;Fang Han
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