逆转肝纤维化的新靶点:PTEN诱导肝星状细胞凋亡?

30872513
2008
H0310.肝损伤、修复与再生
张晓岚
面上项目
教授
河北医科大学
29万元
肝纤维化;肝星状细胞;PTEN;细胞凋亡
2009-01-01到2011-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Regulatory effects of PTEN on proliferation and cell cycle of primary hepatic stellate cells and the mechanisms thereof 会议论文 张晓岚|
2 大鼠纤维化肝组织中PTEN的动态表达及其与肝星状细胞增殖和活化的关系 期刊论文 安君艳|郝礼森|张晓岚|田晓鹏|李玉林|
3 胆汁淤积性肝纤维化大鼠肝组织中PTEN表达与肝星状细胞凋亡的关系研究 期刊论文 姜慧卿|安君艳|李玉林|张晓岚|麻继臣|房澍名|周智宏|姚冬梅|郝礼森|
4 Adenoviral Transduction of PTEN Induces Apoptosis of Cultured Hepatic Stellate Cells 期刊论文 张晓岚|
5 PTEN过表达及其突变对体外活化肝星状细胞凋亡的影响 期刊论文 刘娜|安君艳|李玉林|郝礼森|田晓鹏|姜惠卿|张晓岚|
6 The dynamic change of PTEN expression during fibrogenesis and reversal of rat liver fibrosis induced by CCl4 and its relation with the activation and proliferation of hepatic stellate cells in vivo 会议论文 张晓岚|
7 PTEN Expression is Down-regulated in Liver Tissues of Rats with Hepatic Fibrosis Induced by Biliary Stenosis 期刊论文 张晓岚|
8 Effects of over-expression and mutation of PTEN on the apoptosis of cultured hepatic stellate cells 会议论文 张晓岚|
9 Effects of PTEN gene silencing on collagen metabolism of activated hepatic stellate cells in vitro 会议论文 张晓岚|
10 RNA干扰技术阻断PTEN表达对体外活化肝星状细胞胶原代谢的影响 期刊论文 张晓岚|
11 The dynamic expression of PTEN in fibrogenic liver tissue of rats and its relation with activation and proliferation of hepatic stellate cell 会议论文 张晓岚|
12 大鼠肝纤维化组织中PTEN蛋白的定位分布 期刊论文 安君艳|郝礼森|张晓岚|田晓鹏|刘娜|
13 Effects of PTEN gene silencing on the proliferation and apoptosis of hepatic stellate cells in vitro 会议论文 张晓岚|
14 Over-expression of PTEN by recombinant adenovirus attenuates hepatic fibrosis in rats 会议论文 张晓岚|
15 Effects of adenovirusmediated wild type PTEN gene on apoptosis of hepatic stellate cells in vitro and its potentialmechanism 会议论文 张晓岚|
16 Regulatory effects of PTEN on proliferation and cell cycle of freshly isolated hepatic stellate cells and the mechanisms thereof 会议论文 张晓岚|
17 The down-regulated expression of PTEN in liver tissues of rats with hepatic fibrosis 会议论文 张晓岚|
18 PTEN在肝纤维化大鼠肝组织中的动态表达 期刊论文 郝礼森|田晓鹏|安君艳|张晓岚|刘娜|
19 The dynamic expression of PTEN in fibrogenesis and reversal of rat liver fibrosis and its influences on activation and proliferation of hepatic stellate cells 会议论文 张晓岚|
20 The dynamic change of PTEN expression during fibrogenesis and reversal of rat liver fibrosis induced by CCl4 and its relation with the apoptosis of hepatic stellate cells (HSC) in vivo 会议论文 张晓岚|
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