Perp对T细胞发育和自身耐受的调控及其在自身免疫性疾病中的作用和机制研究

81871300
2018
H1107.自身免疫性疾病
王衍堂
面上项目
研究员
成都医学院
57万元
Perp;自身耐受;T细胞;自身免疫;凋亡
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 苯并噁唑衍生物PO-296对树突状细胞分化及相关指标的影响 期刊论文 朱薪颖;杨苗;徐灿;彭旭;段佳毅;刘丹;王衍堂
2 Pseudolycorine chloride ameliorates Th17 cell-mediated central nervous system autoimmunity by restraining myeloid-derived suppressor cell expansion 期刊论文 Gan Zhang;Xinying Zhu;Fan Yang;Juan Li;Xiao Leng;Chun-Fen Mo;Limei Li;Yan-Tang Wang
3 Activation of Toll-Like Receptor 3 Induces Interleukin-1 Receptor Antagonist Expression by Activating the Interferon Regulatory Factor 3. 期刊论文 Liu Yang;Mo Chun-Fen;Luo Xing-Yan;Li Hua;Guo Hui-Jie;Sun Hai;Hu Song;Li Li-Mei;Wang Yan-Tang;Yang Shu-Xia;Chang Shan;Zou Qiang
4 The p53 effector Perp mediates the persistence of CD4(+) effector memory T-cell undergoing lymphopenia-induced proliferation. 期刊论文 Zhou Yan;Leng Xiao;Mo Chunfen;Zou Qiang;Liu Yang;Wang Yantang
5 伪石蒜碱在制备预防和/或治疗多发性硬化症的药物中的用途 专利 王衍堂;李丽梅;刘阳;冷潇;杨淑霞;罗兴燕;张甘;朱薪颖
6 Regulatory Dendritic Cells Induced by K313 Display Anti-Inflammatory Properties and Ameliorate Experimental Autoimmune Encephalitis in Mice. 期刊论文 Zhou Yan;Leng Xiao;Luo Xingyan;Mo Chunfen;Zou Qiang;Liu Yang;Wang Yantang
7 IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma 期刊论文 Mo Chun-fen;Li Jun;Yang Shu-xia;Guo Hui-jie;Liu Yang;Luo Xing-yan;Wang Yan-tang;Li Min-hui;Li Jing-yi;Zou Qiang
8 PO-322 has potent immunosuppressive activity in vitro and in vivo by selectively inhibiting SGK1 activity. 期刊论文 Lai Yi;Luo Xing-Yan;Guo Hui-Jie;Wang Si-Yu;Xiong Jing;Yang Shu-Xia;Li Li-Mei;Zou Qiang;Mo Chun-Fen;Wang Yan-Tang;Liu Yang
9 Sis-25, a meroditerpenoid derivative with a cyclobutane scaffold, inhibits activated T cell proliferation by targeting GSK3β in vitro and in vivo 期刊论文 Yang Liu;Xingren Li;Xiuyin Wu;Xingyan Luo;Bingchao Yan;Chunfen Mo;Huijie Guo;Shuxia Yang;Yantang Wang;Yi Lai;Pematenzin Puno;Limei Li
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