缺血性脑卒中神经损伤和修复的炎性机制研究
81630026
2016
H09.神经系统
袁增强
重点项目
研究员
中国科学院生物物理研究所
252万元
炎症机制;神经损伤;缺血性脑卒中;神经修复
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A novel m(6)A reader Prrc2a controls oligodendroglial specification and myelination | 期刊论文 | Wu Rong;Li Ang;Sun Baofa;Sun Jian-Guang;Zhang Jinhua;Zhang Ting;Chen Yusheng;Xiao Yujie;Gao Yuhao;Zhang Qingyang;Ma Jun;Yang Xin;Liao Yajin;Lai Wei-Yi;Qi Xiaolong;Wang Shukun;Shu Yousheng;Wang Hai-Lin;Wang Fengchao;Yang Yun-Gui;Yuan Zengqiang |
| 2 | Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology. | 期刊论文 | Cheng Jinbo;Dong Yuan;Ma Jun;Pan Ruiyuan;Liao Yajin;Kong Xiangxi;Li Xiaoheng;Li Shuoshuo;Chen Pingfang;Wang Liang;Yu Ye;Yuan Zengqiang |
| 3 | Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice | 期刊论文 | Cheng Jinbo;Liao Yajin;Dong Yuan;Hu Han;Yang Nannan;Kong Xiangxi;Li Shuoshuo;Li Xiaoheng;Guo Jifeng;Qin Lixia;Yu Jiezhong;Ma Cungen;Li Jianke;Li Mingtao;Tang Beisha;Yuan Zengqiang |
| 4 | HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway | 期刊论文 | Liao Yajin;Cheng Jinbo;Kong Xiangxi;Li Shuoshuo;Li Xiaoheng;Zhang Meijuan;Zhang He;Yang Tianli;Dong Yuan;Li Jun;Xu Yun;Yuan，Zengqiang |
| 5 | c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death | 期刊论文 | Zhou Lujun;Zhang Qiang;Zhang Peng;Sun Lei;Peng Can;Yuan Zengqiang;Cheng Jinbo |
| 6 | Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice | 期刊论文 | Dong Yuan;Li Shuoshuo;Lu Yiming;Li Xiaoheng;Liao Yajin;Peng Zhixin;Li Yunfeng;Hou Lin;Yuan Zengqiang;Cheng Jinbo |
| 7 | Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance | 期刊论文 | Pan Rui-Yuan;Ma Jun;Kong Xiang-Xi;Wang Xiao-Feng;Li Shuo-Shuo;Qi Xiao-Long;Yan Yu-Han;Cheng Jinbo;Liu Qingsong;Jin Wanzhu;Tan Chang-Heng;Yuan Zengqiang |
| 8 | Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Like Behavior in Mice | 期刊论文 | Peng Zhixin;Li Xiaoheng;Li Jun;Dong Yuan;Gao Yuhao;Liao Yajin;Yan Meichen;Yuan Zengqiang;Cheng Jinbo |
| 9 | Mib2 Deficiency Inhibits Microglial Activation and Alleviates Ischemia-Induced Brain Injury | 期刊论文 | Li Xiaoheng;Liao Yajin;Dong Yuan;Li Shuoshuo;Wang Fengchao;Wu Rong;Yuan Zengqiang;Cheng Jinbo |
| 10 | Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice | 期刊论文 | Li Shuoshuo;Liao Yajin;Dong Yuan;Li Xiaoheng;Li Jun;Cheng Yong;Cheng Jinbo;Yuan Zengqiang |
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