炎症小体活化过程中的NF-κB 信号新环路及其可供药物调控的关键节点

91429308
2014
H3504.抗炎与免疫药物药理
顾艳宏
重大研究计划
主任医师
南京医科大学
250万元
炎症小体;线粒体自噬;炎癌转化;胆汁酸代谢
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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2 CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings 期刊论文 Li Q;Zhang X;Wang W;Li L;Xu Q;Wu X;Gu Y
3 Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma 期刊论文 Li Xiang;Zhang Guohui;Wang Yan;Elgehama Ahmed;Sun Yang;Li Lele;Gu Yanhong;Guo Wenjie;Xu Qiang
4 Ginsenosides synergize with mitomycin C in combating human non-small cell lung cancer by repressing Rad51-mediated DNA repair 期刊论文 Zhao M;Wang DD;Che Y;Wu MQ;Li QR;Shao C;Wang Y;Cao LJ;Wang GJ;Hao HP
5 Metabolomics-Proteomics Combined Approach Identifies Differential Metabolism-Associated Molecular Events between Senescence and Apoptosis 期刊论文 Wu Mengqiu;Ye Hui;Shao Chang;Zheng Xiao;Li Qingran;Wang Lin;Zhao Min;Lu Gaoyuan;Chen Baoqiang;Zhang Jun;Wang Yun;Wang Guangji;Hao Haiping
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14 Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis 期刊论文 Hao Haiping;Cao Lijuan;Jiang Changtao;Che Yuan;Zhang Songyang;Takahashi Shogo;Wang Guangji;Gonzalez Frank J.
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