STING信号促进巨噬细胞促炎性免疫应答参与老龄肝脏缺血再灌注损伤的机制研究

81901628
2019
H1105.器官移植与移植免疫
饶竹青
青年科学基金项目
副主任医师
南京医科大学
21万元
巨噬细胞;炎症;干扰素基因刺激分子;自噬;肝脏缺血再灌注损伤
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Travel Grant 奖励 Zhuqing Rao
2 Aging aggravated liver ischemia and reperfusion injury by promoting sting-mediated nlrp3 activation in macrophages. 期刊论文 Zhong Weizhe;Rao Zhuqing;Rao Jianhua;Han Guoyong;Wang Ping;Jiang Tao;Pan Xiongxiong;Zhou Shun;Zhou Haoming;Wang Xuehao
3 MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury 期刊论文 Jian Xu;Dongming Wu;Shun Zhou;Haoran Hu;Fei Li;Zhu Guan;Xinyu Zhan;Yiyun Gao;Ping Wang;Zhuqing Rao
4 Dexmedetomidine preconditioning alleviated murine liver ischemia and reperfusion injury by promoting macrophage M2 activation via PPARγ/STAT3 signaling 期刊论文 Haoming Zhou;Jie Sun;Weizhe Zhong;Xiongxiong Pan;Cunming Liu;Feng Cheng;Ping Wang;Zhuqing Rao
5 Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury 期刊论文 Chengyu Shi;Qi Wang;Zhuqing Rao;Shi Yong;Song Wei;Hao Wang;Xu Lu;Ping Wang;Ling Lu;Haoming Zhou;Feng Cheng
6 Defective mitophagy in aged macrophages promotes mitochondrial DNA cytosolic leakage to activate STING signaling during liver sterile inflammation 期刊论文 Weizhe Zhong;Zhuqing Rao;Jian Xu;Yu Sun;Haoran Hu;Ping Wang;Yongxiang Xia;Xiongxiong Pan;Weiwei Tang;Ziyi Chen;Haoming Zhou;Xuehao Wang
7 Aging aggravated liver ischemia and reperfusion injury by promoting hepatocyte necroptosis in an endoplasmic reticulum stress-dependent manner 期刊论文 Zhong Weizhe;Wang Xiaowei;Rao Zhuqing;Pan Xiongxiong;Sun Yu;Jiang Tao;Wang Ping;Zhou Haoming;Wang Xuehao
8 CCAAT/Enhancer-binding Protein Homologous Protein Promotes ROS-mediated Liver Ischemia and Reperfusion Injury by Inhibiting Mitophagy in Hepatocytes 期刊论文 Shun Zhou;Zhuqing Rao;Yongxiang Xia;Qi Wang;Zheng Liu;Ping Wang;Feng Cheng;Haoming Zhou
9 Obstructive jaundice secondary to fungal infection: a rare case report 期刊论文 Weizhe Zhong;Ping Wang;Chuanyong Zhang;Zhuqing Rao;Xiaowei Wang;Xiongxiong Pan;Haoming Zhou;Xuehao Wang
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