高血糖激活Kupffer细胞ATF6-CHOP通路在肝脏缺血再灌注损伤中的作用及其机制

81871259
2018
H1105.器官移植与移植免疫
饶建华
面上项目
副教授
南京医科大学
57万元
ATF6-CHOP;炎症反应;Kupffer细胞;缺血再灌注损伤;糖尿病
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Hyperglycemia-Triggered Sphingosine-1-Phosphate and Sphingosine-1-Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization. 期刊论文 Hu Y;Yang C;Shen G;Yang S;Cheng X;Cheng F;Rao J;Wang X
2 Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex. 期刊论文 Rao J;Yang C;Yang S;Lu H;Hu Y;Lu L;Cheng F;Wang X
3 miRNA-130b-5p promotes hepatic stellate cell activation and the development of liver fibrosis by suppressing SIRT4 expression 期刊论文 Wang H;Wang Z;Wang Y;Li X;Yang W;Wei S;Shi C;Qiu J;Ni M;Rao J;Cheng F
4 江苏省青年科技奖暨“江苏省十大青年科技之星” 奖励 饶建华
5 一种血管吻合装置 专利 饶建华;刘振川;孙号;罗森;王卫中
6 一种注射装置 专利 饶建华;王永刚;江荣华;隆龙
7 Complete response to immunotherapy combined with an antiangiogenic agent in multiple hepatic metastases after radical surgery for advanced gallbladder cancer: a case report 期刊论文 Rao J;Xia J;Yang W;Wu C;Sha B;Zheng Q;Cheng F;Lu L
8 FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2. 期刊论文 Rao J;Wang H;Ni M;Wang Z;Wang Z;Wei S;Liu M;Wang P;Qiu J;Zhang L;Wu C;Shen H;Wang X;Cheng F;Lu L
9 Macrophage nuclear factor erythroid 2-related factor 2 deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3-mediated RhoA/ROCK pathway in the ischemic liver 期刊论文 Rao J;Qiu J;Ni M;Wang H;Wang P;Zhang L;Wang Z;Liu M;Cheng F;Wang X;Lu L
10 Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway 期刊论文 Yang S;Jiang W;Yang W;Yang C;Yang X;Chen K;Hu Y;Shen G;Lu L;Cheng F;Zhang F;Rao J;Wang X
11 Hyperglycemia-triggered ATF6-CHOP pathway aggravates acute inflammatory liver injury by β-catenin signaling 期刊论文 Yang C;Wang Z;Hu Y;Yang S;Cheng F;Rao J;Wang X
12 Dysregulation of miR-23b-5p promotes cell proliferation via targeting FOXM1 in hepatocellular carcinoma. 期刊论文 Yang X;Yang S;Song J;Yang W;Ji Y;Zhang F;Rao J
13 一种腹腔用于腹腔镜手术的肝门阻断管 专利 饶建华;刘振川;孙号;罗森;王卫中
14 Influence of the Hippo-YAP signalling pathway on tumor associated macrophages (TAMs) and its implications on cancer immunosuppressive microenvironment 期刊论文 Yang W;Yang S;Zhang F;Cheng F;Wang X;Rao J
15 Nogo-B is a key mediator of hepatic ischemia and reperfusion injury. 期刊论文 Rao J;Cheng F;Zhou H;Yang W;Qiu J;Yang C;Ni X;Yang S;Xia Y;Pan X;Zhang F;Lu L;Wang X
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