囊虫DNA疫苗诱导免疫保护机制的蛋白质组学基础

30530660
2005
H2203.寄生虫与感染
孙树汉
重点项目
教授
中国人民解放军第二军医大学
140万元
DNA疫苗;免疫保护;蛋白质组;膜联蛋白;诊断..
2006-01-01到2009-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 A novel mouse model for immunogenic evaluation of human HBV vaccines. 期刊论文 郭瀛军|孙树汉|任丁|
2 DNA Immunization Perturbs the Metabolites of Lipids and Increases the risk of Atherogenesis. 期刊论文 严诗楷|张卫东|孙树汉|杨富|
3 识别单链 RNA 病毒的猪 TLR7 基因的克隆及功能分析 会议论文 孙树汉|章意亮|
4 膜联蛋白在毕赤酵母中的表达及抗凝活性研究 奖励 孙树汉|杨湘越|
5 Expression of HBV Proteins in Transgenic Mice Disturbs Liver Lipid Metabolism and Induces Oxidative Stress. 期刊论文 张卫东|严诗楷|孙树汉|杨富|
6 Augmented humoral and cellular immune response of hepatitis B virus DNA vaccine by micro-needle vaccination using Flt 3L as an adjuvant. 期刊论文 周奇|孙树汉|
7 Molecular cloning and functional characterization of porcine toll-like receptor 7 involoved in recognition of single-stranded RNA virus/ssRNA. 期刊论文 章意亮|郭瀛军|孙树汉|
8 Combined DNA vaccination against three animal viruses elicits decreased immunogenicity of a single plasmid 期刊论文 王开宇|孙树汉|
9 P53 对 miR-17-92 簇的负向调节在缺氧诱导的细胞凋亡中具有重要作用 会议论文 薛赓|孙树汉|
10 Augmented induction of CD8+ cytotoxic T-cell response and antitumour effect by DCs pulsed with virus-like particles packaging with CpG. 期刊论文 宋淑霞|孙树汉|
11 核酸疫苗免疫效力的抑制性因素及其作用机制研究 会议论文 王越|孙树汉|
12 Multiepitope Peptide-Loaded Virus-Like Particles as a Vaccine Against Hepatitis B Virus–Related Hepatocellular Carcinoma. 期刊论文 何晓文|孙树汉|丁飞翔|王芳|
13 军队四种主要传染病新型疫苗及免疫佐剂研究 奖励 孙树汉|
14 慢性乙型肝炎致病机制及其防治的“组学”研究 会议论文 孙树汉|杨富|
15 Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7 期刊论文 郭瀛军|章意亮|孙树汉|
16 血清 DNA 结合蛋白对核酸疫苗免疫效力的影响及其意义 会议论文 王越|孙树汉|郭瀛军|
17 Optimization strategy for plasmid DNAs containing multiple-epitopes of foot-and-mouth disease virus by cis-expression with IL-2. 期刊论文 张洪英|孙树汉|
18 乙肝病毒抗原表达引起肝脏的脂质代谢紊乱及氧化应激损伤 会议论文 杨富|孙树汉|
19 Enhanced Capacity of Antigen Presentation of HBc-VLP-Pulsed RAW264.7 Cells Revealed by Proteomics Analysis. 期刊论文 王芳|孙树汉|杨富|
20 Novel chitosan derivative nanoparticles enhance the immunogenicity of a DNA Vaccine encoding hepatitis B virus core antigen in mice. 期刊论文 孙树汉|姜磊|
21 Up-Regulated MicroRNA-143 Transcribed by Nuclear Factor kappa B Enhances Hepatocarcinoma Metastasis by Repressing Fibronectin Expression . 期刊论文 孙树汉|张小英|刘善荣|
22 DNA 结合蛋白对基因治疗载体体内转染效率的影响及机制 会议论文 孙树汉|王越|
23 血清 DNA 结合蛋白 SAP 对核酸疫苗免疫效力的影响及其意义 会议论文 孙树汉|
24 Extracellular DNA-binding proteins and DNA vaccine:Human Serum Amyloid P (hSAP) as a DNA vaccine barrier 会议论文 王越|孙树汉|
25 核酸疫苗研究的十年 会议论文 孙树汉|
26 Comparative proteomics analysis to annexin B1 DNA and protein vaccinatin in mice. 期刊论文 李德安|孙树汉|
27 Proteomic analysis of augmented immune responses in mouse by prime-and-boost immunization strategy with DNA vaccine coding HBsAg and rHBsAg protein. 期刊论文 王越|孙树汉|
28 An Altered Pattern of Liver Apolipoprotein A-I Isoforms Is Implicated in Male Chronic Hepatitis B Progression. 期刊论文 殷一旋|孙树汉|杨富|
29 Autoimmune vitiligo induced by vaccination with pcDNA-B1 is accompanied by the suppression of regulatory T cells 会议论文 王芳|孙树汉|
30 HBx down-regulates protein L-isoaspartyl methyltransferase expression mediated by STRAP and Nm23-H1 through activation of PI3K pathway 会议论文 何颖|孙树汉|
31 Screening, purification, and identification of annexin B1 mutants with high phosphatidylserine-binding activity and reduced immunogenicity. 期刊论文 孙树汉|王芳|
32 Evaluation of antitumor immunity efficacy of epitope-based vaccine with B16 cell line coexpressing HLA-A2/H-2kb and CTL multiepitope in HLA transgenic mice. 期刊论文 宋淑霞|孙树汉|
33 RRESPONDENCE:Is MicroRNA-143 really a turncoat of tumor suppressor microRNA in HBV-related hepatocarcinoma? 期刊论文 孙树汉|张小英|刘善荣|
34 Vaccination with combination of Fit 3L and RANTES in a DNA prime-protein boost regimen elicits strong cell-mediated immunity and antitumor effect. 期刊论文 孙树汉|宋淑霞|
35 Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis 期刊论文 孙树汉|颜宏利|
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享