促神经再生的氮杂类黄酮的设计与合成及其增殖分化机制

21878022
2018
B0810.农业与食品化工
梁建华
面上项目
教授
北京理工大学
65万元
药物构效解析;干细胞;神经再生;结构修饰;天然药物工程
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 原小檗碱骨架的合成及其抗炎活性研究进展 期刊论文 刘兴周;于明加;梁建华
2 Design and Synthesis of Novel Pro-neurogenic Stimulators 会议论文 Si-Si LIU;Cong-Xuan MA;Jian-Hua LIANG
3 Synthesis and Structure-bactericidal Activity Relationships of Non-ketolides: 9-Oxime Clarithromycin 11,12-Cyclic Carbonate Featured with Three- to Eight-atom-length Spacers at 3-OH 期刊论文 Li Xue Meng;Lv Wei;Guo Si Yang;Li Ya Xin;Fan Bing Zhi;Cushman Mark;Kong Fan Sheng;Zhang Jun;Liang Jian Hua
4 Design, synthesis and in vivo hypoglycemic activity of disaccharide C-glycoside chalcones 会议论文 Cong-Xuan MA;Hong-Peng LI;Hai-Rui REN;Jian-Hua LIANG
5 A Potential Strategy for Treatment of Neurodegenerative Disorders by Regulation of Adult Hippocampal Neurogenesis in Human Brain 期刊论文 Wei-Song Xie;Kiran Shehzadi;Hong-Le Ma;Jian-Hua Liang
6 Design, Synthesis and Biological Evaluation of Conjugates of 3-O-Descladinose-azithromycin and Nucleobases against rRNA A2058G- or A2059G-Mutated Strains 期刊论文 Lian Xiaotian;Liu Wentian;Fan Bingzhi;Yu Mingjia;Liang Jian-Hua
7 WS6 Induces Adult Hippocampal Neurogenesis in Correlation to its Antidepressant Effect on the Alleviation of Depressive-like Behaviors of Rats 期刊论文 Zhang Heao;Xiang Lin;Yang Liang;Wu Si;Liu Sisi;Zhao Juan;Song Da;Ma Congxuan;Ni Junjun;Quan Zhenzhen;Liang Jianhua;Qing Hong
8 Design, Synthesis and Structure-activity Relationships of Novel 15-Membered Macrolides: Quinolone/quinoline-containing Sidechains Tethered to the C-6 Position of Azithromycin Acylides 期刊论文 Fan Bing-Zhi;Hiasa Hiroshi;Lv Wei;Brody Scott;Yang Zhao-Yong;Aldrich Courtney;Cushman Mark;Liang Jian-Hua
9 一种非葡萄糖碳苷二氢查尔酮及其制备方法 专利 梁建华;邓玉林;辛念;戴荣继;孟薇薇
10 一种氮杂碳苷查尔酮及其制备方法 专利 邓玉林;梁建华;辛念;戴荣继;孟薇薇
11 Design and synthesis of novel macrolones bridged with linkers from 11,12-positions of macrolides 期刊论文 Xie-Peng Liu;Wei Lv;Fei Zhao;Jing Ding;Jue-Ru Zhang;Feng Xue;Jian-Zhong Zhang;Li-Yong Liu;Mark Cushman;Yun Li;Jian-Hua Liang
12 Design, Synthesis and Structure-activity Relationships of Novel Macrolones: Hybrids of 2-Fluoro 9-Oxime Ketolides and Carbamoyl Quinolones with Highly Improved Activity against Resistant Pathogens 期刊论文 Ma Cong Xuan;Lv Wei;Li Ya Xin;Fan Bing Zhi;Han Xu;Kong Fan Sheng;Tian Jing Chao;Cushman Mark;Liang Jian Hua
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