雷帕霉素靶蛋白（mTOR）通路对尼罗罗非鱼淋巴细胞介导适应性免疫的调控机制

31872591
2018
C1907.水产生物免疫学
杨嘉龙
面上项目
教授
华东师范大学
59万元
淋巴细胞;适应性免疫;硬骨鱼;雷帕霉素靶蛋白通路;免疫调控
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 c-Raf participates in adaptive immune response of Nile tilapia via regulating lymphocyte activation 期刊论文 Wei Xiumei;Zhao Tianyu;Ai Kete;Zhang Yu;Li Huiying;Yang Jialong
2 Akt1/mTORC1 signaling modulates adaptive immune response of Nile tilapia by promoting lymphocyte activation and proliferation 期刊论文 Ai Kete;Yan Jie;Li Kang;Li Cheng;Zhang Yu;Liang Wei;Li Jiaqi;Wei Xiumei;Yang Jialong
3 I kappa B alpha phosphorylation and associated NF-kappa B activation are essential events in lymphocyte activation, proliferation, and anti-bacterial adaptive immune response of Nile tilapia 期刊论文 Li Cheng;Yu Junkun;Ai Kete;Li Huiying;Zhang Yu;Zhao Tianyu;Wei Xiumei;Yang Jialong
4 Fish NF-kappa B couples TCR and IL-17 signals to regulate ancestral T-cell immune response against bacterial infection 期刊论文 Wei Xiumei;Li Cheng;Zhang Yu;Li Kang;Li Jiaqi;Ai Kete;Li Kunming;Zhang Jiansong;Yang Jialong
5 The evolutionarily conserved MAPK/Erk signaling promotes ancestral T-cell immunity in fish via c-Myc-mediated glycolysis 期刊论文 Wei Xiumei;Zhang Yu;Li Cheng;Ai Kete;Li Kang;Li Huiying;Yang Jialong
6 IL-2-mTORC1 signaling coordinates the STAT1/T-bet axis to ensure Th1 cell differentiation and anti-bacterial immune response in fish 期刊论文 Kete Ai;Kang Li;Xinying Jiao;Yu Zhang;Jiaqi Li;Qian Zhang;Xiumei Wei;Jialong Yang
7 Essential role of 4E-BP1 for lymphocyte activation and proliferation in the adaptive immune response of Nile tilapia 期刊论文 Li Cheng;Li Kang;Li Kunming;Ai Kete;Zhang Yu;Zhang Jiansong;Li Jiaqi;Wei Xiumei;Yang Jialong
8 Ca2+ -Calcineurin Axis-Controlled NFAT Nuclear Translocation Is Crucial for Optimal T Cell Immunity in an Early Vertebrate 期刊论文 Wei Xiumei;Li Huiying;Zhang Yu;Li Cheng;Li Kang;Ai Kete;Yang Jialong
9 S6K1/S6 axis-regulated lymphocyte activation is important for adaptive immune response of Nile tilapia 期刊论文 Kunming Li;Xiaotong Shen;Hong Qiu;Tianyu Zhao;Kete Ai;Cheng Li;Yu Zhang;Kang Li;Ming Duan;Xiumei Wei;Jialong Yang
10 ZAP70 activation is an early event of T cell immunity that involved in the anti-bacterial adaptive immune response of Nile tilapia 期刊论文 Li Jiaqi;Liang Wei;Li Kang;Jiao Xinying;Ai Kete;Zhang Yu;Wei Xiumei;Yang Jialong
11 The involvement of TNF-alpha and TNF-beta as proinflammatory cytokines in lymphocyte-mediated adaptive immunity of Nile tilapia by initiating apoptosis 期刊论文 Li Kang;Qiu Hong;Yan Jie;Shen Xiaotong;Wei Xiumei;Duan Ming;Yang Jialong
12 High-fat diet blunts T-cell responsiveness in Nile tilapia 期刊论文 Kunming Li;Jiahua Zhu;Kang Li;Wei Liang;Jiansong Zhang;Qian Zhang;Xinying Jiao;Xiaodan Wang;Xiumei Wei;Jialong Yang
13 抗罗非鱼T淋巴细胞表面膜蛋白CD3ε单克隆抗体的制备方法和应用 专利 杨嘉龙;韦秀梅;李康
14 Raptor/mTORC1 Acts as a Modulatory Center to Regulate Anti-bacterial Immune Response in Rockfish 期刊论文 Li Kang;Wei Xiumei;Zhang Libin;Chi Heng;Yang Jialong
15 Activated T cells are the cellular source of IL-22 that enhances proliferation and survival of lymphocytes in Nile tilapia. 期刊论文 Xinying Jiao;Kang Li;Ming Geng;Kunming Li;Wei Liang;Jiansong Zhang;Qian Zhang;Haiyou Gao;Xiumei Wei;Jialong Yang
16 An atypical KLRG1 in Nile tilapia involves in adaptive immunity as a potential marker for activated T lymphocytes 期刊论文 Zhang Yu;Li Kang;Li Cheng;Liang Wei;Li Kunming;Li Jiaqi;Wei Xiumei;Yang Jialong
17 Interleukin-2 inducible T cell kinase (ITK) may participate in the anti-bacterial immune response of Nile tilapia via regulating T-cell activation 期刊论文 Wei Liang;Kunming Li;Qian Zhang;Kang Li;Kete Ai;Jiansong Zhang;Xinying Jiao;Jiaqi Li;Xiumei Wei;Jialong Yang
18 IL-10 Negatively Controls the Primary T Cell Response of Tilapia by Triggering the JAK1/STAT3/SOCS3 Axis That Suppresses NF-κB and MAPK/ERK Signaling 期刊论文 Kang Li;Jiaqi Li;Xiumei Wei;Junya Wang;Ming Geng;Kete Ai;Wei Liang;Jiansong Zhang;Kunming Li;Haiyou Gao;Jialong Yang
19 Involvement of H-Ras in the adaptive immunity of Nile tilapia by regulating lymphocyte activation 期刊论文 Wei Xiumei;Zhao Tianyu;Zhang Yu;Ai Kete;Li Huiying;Yang Jialong
20 Ancestral T Cells in Fish Require mTORC1-Coupled Immune Signals and Metabolic Programming for Proper Activation and Function 期刊论文 Wei Xiumei;Ai Kete;Li Huiying;Zhang Yu;Li Kang;Yang Jialong
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