孤独症谱系障碍诊断和预测蛋白标志物的筛选验证及相关机制研究
31870825
2018
C2103.生命组学技术
沈立明
面上项目
副教授
深圳大学
59万元
疾病相关蛋白质组;孤独症谱系障碍;靶标蛋白质组学;血液蛋白质组学;疾病蛋白质标志物
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Trace Element Changes in the Plasma of Autism Spectrum Disorder Children and the Positive Correlation Between Chromium and Vanadium | 期刊论文 | Jun Zhang;Jing Lin;Xiying Zhao;Fang Yao;Chengyun Feng;Zhijun He;Xueshan Cao;Yan Gao;Naseer Ullah Khan;Margy Chen;Peng Luo;Liming Shen |
| 2 | Targeted metabolomics study of early pathological features in hippocampus of triple transgenic Alzheimer's disease male mice | 期刊论文 | Zhao Yuxi;Chen Haiquan;Iqbal Javed;Liu Xukun;Zhang Huajie;Xiao Shifeng;Jin Na;Yao Fang;Shen Liming |
| 3 | Trace elements in children with autism spectrum disorder: A meta-analysis based on case-control studies | 期刊论文 | Jun Zhang;Xi Li;Liming Shen;Naseer Ullah Khan;Xiao Zhang;Lulu Chen;Huan Zhao;Peng Luo |
| 4 | A Combined Proteomics and Metabolomics Profiling to Investigate the Genetic Heterogeneity of Autistic Children | 期刊论文 | Liming Shen;Huajie Zhang;Jing Lin;Yan Gao;Margy Chen;Naseer Ullah Khan;Xiaoxiao Tang;Qi Hong;Chengyun Feng;Yuxi Zhao;Xueshan Cao |
| 5 | iTRAQ-Based Proteomics Analysis of Rat Cerebral Cortex Exposed to Valproic Acid before Delivery | 期刊论文 | Jing Lin;Kaoyuan Zhang;Xueshan Cao;Yuxi Zhao;Naseer Ullah Khan;Xukun Liu;Xiaoxiao Tang;Margy Chen;Huajie Zhang;Liming Shen |
| 6 | Potential biomarkers identified in plasma of patients with gestational diabetes mellitus | 期刊论文 | Huajie Zhang;Yuxi Zhao;Danqing Zhao;Xinqian Chen;Naseer Ullah Khan;Xukun Liu;Qihong Zheng;Yi Liang;Yuhua Zhu;Javed Iqbal;Jing Lin;Liming Shen |
| 7 | 一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用(PCT专利) | 专利 | 姚芳;沈立明 |
| 8 | 一种用于检测孤独症谱系障碍的诊断标志物、设备及应用 | 专利 | 沈立明;冯承芸;赵丹青 |
| 9 | 血液差异蛋白组合在制备用于检测ASD试剂中的应用 | 专利 | 沈立明;曹雪杉;冯承芸;高岩 |
| 10 | Biomarkers in Autism Spectrum Disorders: Current Progress | 期刊论文 | Liming Shen;XuKun Liu;Huajie Zhang;Jing Lin;Chengyun Feng;Javed Iqbal |
| 11 | Ultrasensitive Detection of Exosome Using Biofunctionalized Gold Nanorods on a Silver-Island Film | 期刊论文 | Khan Naseer Ullah;Muhammad Zahir;Liu Xukun;Lin Jing;Zheng Qihong;Zhang Huajie;Malik Samiullah;He Hua;Shen Liming |
| 12 | Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer's Mice Model: A Proteomic Study | 期刊论文 | Du Xiubo;Shi Qingqing;Zhao Yuxi;Xie Yongli;Li Xuexia;Liu Qiong;Iqbal Javed;Zhang Huajie;Liu Xukun;Shen Liming |
| 13 | Metabolic characteristics of plasma bile acids in patients with intrahepatic cholestasis of pregnancy‑mass spectrometric study | 期刊论文 | Qihong Zheng;Liming Shen;Danqing Zhao;Huajie Zhang;Yi Liang;Yuhua Zhu;Naseer Ullah Khan;Xukun Liu;Jun Zhang;Jing Lin;Xiaoxiao Tang |
| 14 | Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Revealed Mitochondrial Damage and Synaptic Impairments in Association with 3 × Tg-AD Mice Model. | 期刊论文 | Liming Shen;Aochu Yang;Xinqian Chen;Shifeng Xiao;Xukun Liu;Jing Lin;Yuxi Zhao;Kaoyuan Zhang;Cuihua Li;Junyan Ke;Huajie Zhang;Naseer Ullah Khan |
| 15 | Proteomics Study of Peripheral Blood Mononuclear Cells (PBMCs) in Autistic Children | 期刊论文 | Liming Shen;Chengyun Feng;Kaoyuan Zhang;Youjiao Chen;Yan Gao;Junyan Ke;Xinqian Chen;Jing Lin;Cuihua Li;Javed Iqbal;Yuxi Zhao;Weibin Wang |
| 16 | Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease | 期刊论文 | Yuanyuan Shen;Lingchen Hua;Chih-Kuang Yeh;Liming Shen;Ming Ying;Zaijun Zhang;Gong-Ping Liu;Shupeng Li;Siping Chen;Xin Chen;Xifei Yang |
| 17 | Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy | 期刊论文 | Liming Shen;Danqing Zhao;Youjiao Chen;Kaoyuan Zhang;Xinqian Chen;Jing Lin;Cuihua Li;Javed Iqbal;Yuxi Zhao;Yi Liang;Yan Wei;Chengyun Feng |
| 18 | 一种基于免疫荧光增强的外泌体定量检测方法(申请) | 专利 | 沈立明;何化;纳赛尔·哈塔克 |
| 19 | 一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用(已授权) | 专利 | 姚芳;沈立明 |
| 20 | Advances in Biomarker Studies in Autism Spectrum Disorders | 专著 | Liming Shen;Yuxi Zhao;Huajie Zhang;Chenyun Feng;Yan Gao;Danqing Zhao;Sijian Xia;Qi Hong;Javed Iqbal;Xukun LIU;Fang Yao |
| 21 | Protein Biomarkers of Autism Spectrum Disorder Identified by Computational and Experimental Methods | 期刊论文 | Yao Fang;Zhang Kaoyuan;Feng Chengyun;Gao Yan;Shen Liming;Liu Xukun;Ni Jiazuan |
| 22 | Alzheimer’s Disease Is Responsible for Progressive Age-Dependent Differential Expression of Various Protein Cascades in Retina of Mice | 期刊论文 | Javed Iqbal;Kaoyuan Zhang;Na Jin;Yuxi Zhao;Xukun Liu;Qiong Liu;Jiazuan Ni;Liming Shen |
| 23 | Oxidative Stress in Autism Spectrum Disorder—Current Progress of Mechanisms and Biomarkers | 期刊论文 | Xukun Liu;Jing Lin;Huajie Zhang;Naseer Ullah Khan;Jun Zhang;Xiaoxiao Tang;Xueshan Cao;Liming Shen |
| 24 | Insights into predicting diabetic nephropathy using urinary biomarkers | 期刊论文 | Naseer Ullah Khan;Jing Lin;Xukun Liu;Haiying Li;Wei Lu;Zhuning Zhong;Huajie Zhang;Muhammad Waqas;Liming Shen |
| 25 | Synthesis of gold nanorods and their performance in the field of cancer cell imaging and photothermal therapy | 期刊论文 | Naseer Ullah Khan;Jing Lin;Muhammad Rizwan Younas;Xukun Liu;Liming Shen |
| 26 | 一组血清差异蛋白组合在制备用于检测阿尔茨海默症的试剂中的应用(已授权) | 专利 | 姚芳;沈立明;刘琼 |
查看更多信息请先登录或注册
