MG53调节心脏辅助亚基KChIP2表达的分子机制及其在心脏电稳态调节中的作用

31371159
2013
C1101.循环与血液生理
刘杰
面上项目
教授
深圳大学
86万元
MG53;KChIP2;瞬间外向钾电流;心电稳定性;心肌细胞
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 High-mobility group box 1 (HMGB1) impaired cardiac excitation-contraction coupling by enhancing the sarcoplasmic reticulum (SR) Ca2+ leak through TLR4-ROS signaling in cardiomyocytes 期刊论文 Zhang Cuicui;Mo Miaohua;Ding Wenwen;Liu Wenjuan;Yan Dewen;Deng Jianxin;Luo Xinping;Liu Jie
2 Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway 期刊论文 Ding Wenwen;Dong Ming;Deng Jianxin;Yan Dewen;Liu Yun;Xu Teng;Liu Jie
3 STIM1蛋白在相关疾病风险诊断中的应用 专利 刘杰;董鸣
4 Increased expression of STIM1/Orai1 in platelets of stroke patients predictive of poor outcomes 期刊论文 Dong M.;Zheng N.;Ren L. J.;Zhou H.;Liu J.
5 Resveratrol and polydatin as modulators of Ca2+ mobilization in the cardiovascular system 期刊论文 Liu Wenjuan;Chen Peiya;Deng Jianxin;Lv Jingzhang;Liu Jie
6 正常与疾病心脏兴奋-收缩偶联调节机制的研究 奖励 刘杰;刘文娟;邓建新;王刚;姜昕;吕敬章
7 Toll-like receptor 4 induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca2+ leakage promote cardiac contractile dysfunction in sepsis. 期刊论文 Yang J;Zhang R;Jiang X;Lv J;Li Y;Ye H;Liu W;Wang G;Zhang C;Zheng N;Dong M;Wang Y;Chen P;Santosh K;Jiang Y;Liu J
8 KCNE2 modulates cardiac L-type Ca2+ channel 期刊论文 Wenjuan Liu;Jianxin Deng;Gang Wang;Cuicui Zhang;Xinping Luo;Dewen Yan;Qingning Su;Jie Liu
9 MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress 期刊论文 Zhang Caimei;Chen Biyi;Wang Yihui;Guo Ang;Tang Yiqun;Khataei Tahsin;Shi Yun;Kutschke William J.;Zimmerman Kathy;Weiss Robert M.;Liu Jie;Benson Christopher J.;Hong Jiang;Ma Jianjie;Song Long-Sheng
10 Manipulation of KCNE2 expression modulates action potential duration and I-to and I-K in rat and mouse ventricular myocytes 期刊论文 Liu Wen-juan;Deng Jian-xin;Wang Gang;Gao Kai-ping;Lin Ze-xun;Liu Shuai-ye;Wang Yong-hui;Liu Jie
11 细胞钙信号原理及病理调控 奖励 王世强;程和平;徐明;魏朝亮;张幼怡;刘杰;王秀杰;王刚;陶瑾;朱小君;王显花;王猛
12 正常与疾病心脏兴奋-收缩偶联调节机制的研究 奖励 刘杰;邓建新;姜昕;刘文娟;王刚;林泽鹏
13 trans-Polydatin protects the mouse heart against ischemia/reperfusion injury via inhibition of the renin-angiotensin system (RAS) and Rho kinase (ROCK) activity 期刊论文 Ming Dong;Songyan Liao;Yawen Chen;Na Zheng;Jing Ma;Zhaowen Xiao;Ye Liu;Wa Ding;Jie Liu
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