Dapper蛋白在小鼠胚胎发育和器官形成中的作用及其机制

30930050
2009
C1203.早期胚胎发育及细胞谱系建立
陈晔光
重点项目
教授
清华大学
160万元
基因敲除;Wnt;Dapper;器官发育;TGF-β
2010-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development 期刊论文 Ning W|Dong Y|Yu M|Zhang L|Yan X|Sun J|Qiao L|Geng H|Gao X|
2 Design of stapled α-helical peptides to specifically activate Wnt/β-catenin signaling 期刊论文 Cui HK, Zhao B, Li Y, Guo Y, Hu H, Liu L,|Chen YG|
3 TSC-22 Promotes Transforming Growth Factor beta-Mediated Cardiac Myofibroblast Differentiation by Antagonizing Smad7 Activity 期刊论文 Chen, Ye-Guang|Zhang, Junyu|Pan, Lin|Wang, Peng|Xue, Hua|Zhang, Long|Gao, Xia|Zhao, Xingang|Ning, Yuanheng|
4 Identification of Novel Rare Mutations of DACT1 in Human Neural Tube Defects 期刊论文 Wang, Hong-Yan|Ding, Yi|Lei, Yun-Ping|Yang, Xue-Yan|Xie, Guo-Ming|Wen, Jun|Cai, Chun-Quan|Li, Hong|Chen, Ying|
5 Disruption of the Dapper3 Gene Aggravates UreteralObstruction-mediated Renal Fibrosis by Amplifying Wnt/β-catenin Signaling 期刊论文 Xue H, Xiao ZC, Zhang J, Wen J, Wang Y, Chang Z,Zh|Chen YG|
6 c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor 期刊论文 Feng X|Luo S|Gao C|Chen YG|
7 BMP4 Signaling Acts via Dual Specificity Phosphatase 9 to Control ERK Activity in Mouse Embryonic Stem Cells 期刊论文 Wang L|Lu D|Lu D|Chi X|Chi X|Teng Y|Teng Y|Hou N|Hou N|
8 Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration 期刊论文 Xu, Huaxi|Zhang, Yun-wu|Chen, Yaomin|Huang, Xiumei|Zhou, Fangfang|Wang, Weiwei|Xian, Bo|Zhang, Xian|Masliah, Eliezer|
9 Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation 期刊论文 Chen, Ye-Guang|Cao, Weipeng|Bao, Lan|Zuo, Wei|Xie, Guoming|Cai, Tiantian|Fu, Wei|Zhang, Jian|Wu, Wei|
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