外泌体miR-21调控气道上皮细胞与巨噬细胞交互对话对COPD小气道重塑的影响及机制研究
81770042
2017
H0105.慢性阻塞性肺疾病
孙圣华
面上项目
教授
中南大学
55万元
气道上皮细胞;微小RNA-21;上皮间质转化;慢性阻塞性肺疾病;外泌体
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A Novel Murine Chronic Obstructive Pulmonary Disease Model and the Pathogenic Role of Micro RNA-21 | 期刊论文 | He Shengyang;Li Liqiu;Sun Shenghua;Zeng Zhengpeng;Lu Junjuan;Xie Lihua |
| 2 | MicroRNA-21 aggravates chronic obstructive pulmonary disease by promoting autophagy | 期刊论文 | Zhengpeng Zeng;ShengYang He;JunJuan Lu;Chun Liu;Hua Lin;ChaoQun Xu;LiHua Xie;ShengHua Sun |
| 3 | the protective role of bronchial epithelial cells derived exosome in COPD | 会议论文 | He shengyang;Hu mengyun;Zeng zhengpeng;Lu junjuan;Xie lihua;Sun shenghua |
| 4 | MiR-21对香烟烟雾提取物诱导的巨噬细胞自噬、增殖及凋亡的影响 | 期刊论文 | 曾征鹏;孙圣华;谢丽华 |
| 5 | Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization. | 期刊论文 | Lihua Xie;Duanni Chen;Georges E Grau;Li Zhang;Mengyun Hu;Caihong Liu;Guanzhi Zhou;Daniela Traini;Zhengpeng Zeng;Junjuan Lu;Shenghua Sun;Shengyang He |
| 6 | The effects of the miR-21/SMAD7/TGF-β pathway on Th17 cell differentiation in COPD | 期刊论文 | Lihua Xie;Liqiu Li;Lili Chen;Zhengpeng Zeng;Xiang Mei;Junjuan Lu;Shenghua Sun;Mubin Zhong;Shengyang He |
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